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Sodium deoxycholate - 97%, high purity , CAS No.302-95-4

24 Citations

≥97%

CAS#: 302-95-4
Formula: C₂₄H₃₉O₄Na
Molecular Weight: 414.56
Beilstein Registry Number: 3581950
EC Number: 206-132-7
PubChem CID: 23668196

Item Number

S579505

Grouped product items
SKU	Size	Availability	Price
S579505-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$19.90
S579505-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$48.90
S579505-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$128.90
S579505-250g	250g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$291.90
S579505-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$539.90

View related series

Bile alkanes ( bile acids ) [ steroids ] G protein-coupled Bile Acid Receptor 1 GPCR/G Protein Steroids

Basic Description

Synonyms	Kybella \| sodium (3alpha,5beta,12alpha)-3,12-dihydroxycholan-24-oate \| Deoxycholic acid sodium salt \| HY-N0593A \| Na-Desoxycholat \| ISOQUINOLINIUM, 2,2'-(1,5-PENTANEDIYLBIS(OXY(3-OXO-3,1-PROPANEDIYL)))BIS(1-((3,4-DIMETHOXYPHENYL)METHYL)-1,2,3,4-TETRAHYDRO
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	Increase the dissolution of fat to promote its absorption in the intestine. A water-soluble ionic detergent used to extract membrane receptors and other plasma membrane proteins. Reportedly inducible β- Tyrosine phosphorylation of Catenin and subsequent t
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Note	如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
Product Description	Deoxycholic acid sodium salt, also known as Sodium Deoxycholate, is a highly versatile ionic detergent utilized for its exceptional ability to solubilize membrane-bound proteins and lyse cells. Its mechanism involves disrupting cell membranes and dissolving hydrophobic molecules, making it an invaluable reagent in scientific research applications. In protein research, it plays a pivotal role in solubilizing proteins, particularly those embedded in membranes, enabling their extraction, purification, and subsequent analysis. Moreover, Sodium Deoxycholate extends its utility to nucleic acid extraction from cells and tissues. By lysing cells and disrupting cellular structures, it facilitates the release and purification of nucleic acids, proving valuable in cell biology and biochemical research. Beyond these applications, its effectiveness in cell lysis processes positions it as a valuable tool for breaking down cells and releasing their contents, finding applications in diverse biological studies, encompassing microscopy, cell biology, and biochemical research.

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXRA Tclin Retinoid X receptor alpha (3637 Activities)

Discover Target: RXRA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GSTO1 Tchem Glutathione transferase omega 1 (164 Activities)

Discover Target: GSTO1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Cruzipain (33337 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ppard Peroxisome proliferator-activated receptor delta (358 Activities)

Discover Target: Ppard

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	sodium;(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
INCHI	InChI=1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
InChi Key	FHHPUSMSKHSNKW-SMOYURAASA-M
Canonical SMILES	CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
Isomeric SMILES	C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]
WGK Germany	3
RTECS	FZ2250000
PubChem CID	23668196
Molecular Weight	414.56
Beilstein	3581950

Certificates

Certificate of Analysis(COA)

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Find and download the COA for your product by matching the lot number on the packaging.

33 results found

Lot Number	Certificate Type	Date	Item
K2427729	Certificate of Analysis	Dec 07, 2024	S579505
K2427727	Certificate of Analysis	Dec 07, 2024	S579505
K2427687	Certificate of Analysis	Dec 07, 2024	S579505
K2427686	Certificate of Analysis	Dec 07, 2024	S579505
K2427684	Certificate of Analysis	Dec 07, 2024	S579505
J2409812	Certificate of Analysis	Oct 16, 2024	S579505
J2409804	Certificate of Analysis	Oct 16, 2024	S579505
H2426417	Certificate of Analysis	Aug 30, 2024	S579505
H2426416	Certificate of Analysis	Aug 30, 2024	S579505
H2426415	Certificate of Analysis	Aug 30, 2024	S579505
H2426414	Certificate of Analysis	Aug 30, 2024	S579505
G2404249	Certificate of Analysis	Jun 25, 2024	S579505
G2404251	Certificate of Analysis	Jun 25, 2024	S579505
G2404250	Certificate of Analysis	Jun 25, 2024	S579505
D2415156	Certificate of Analysis	Mar 30, 2024	S579505
D2415155	Certificate of Analysis	Mar 30, 2024	S579505
D2415154	Certificate of Analysis	Mar 30, 2024	S579505
D2415153	Certificate of Analysis	Mar 30, 2024	S579505
B2401290	Certificate of Analysis	Jan 23, 2024	S579505
B2401291	Certificate of Analysis	Jan 23, 2024	S579505
B2401292	Certificate of Analysis	Jan 23, 2024	S579505
B2401293	Certificate of Analysis	Jan 23, 2024	S579505
B2401294	Certificate of Analysis	Jan 23, 2024	S579505
B2401295	Certificate of Analysis	Jan 23, 2024	S579505
B2401289	Certificate of Analysis	Jan 23, 2024	S579505
J2307102	Certificate of Analysis	Sep 20, 2023	S579505
J2307103	Certificate of Analysis	Sep 20, 2023	S579505
J2307101	Certificate of Analysis	Sep 20, 2023	S579505
D2314458	Certificate of Analysis	Apr 19, 2023	S579505
D2314459	Certificate of Analysis	Apr 19, 2023	S579505
D2314461	Certificate of Analysis	Apr 19, 2023	S579505
D2314466	Certificate of Analysis	Apr 19, 2023	S579505
D2314706	Certificate of Analysis	Apr 19, 2023	S579505

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Chemical and Physical Properties

Solubility	Soluble in water (330 g/l) at 15 °C, DMSO, methanol, and ethanol (very slightly).
Sensitivity	Hygroscopic
Specific Rotation[α]	42° (C=2,H2O)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	FZ2250000

Alternative Products

FAQs and Articles

FAQ

Cross-linking ChIP-Seq (X-ChIP-Seq) protocol

Categories: Protocols

Tags:

Electrophoresis Cross-linking ChIP

Chromatin preparation from tissues for chromatin immunoprecipitation (ChIP)

Categories: Protocols

Tags:

Electrophoresis ChIP Lysis buffer Aprotinin

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jing Zhang, Kairu Liu, Xiaojuan Duan, Xuhao Wang, Wupeng Ge, Wenping Jin. (2023) Restoration of Choujiu Koji and evaluation of its brewing performance. LWT-FOOD SCIENCE AND TECHNOLOGY, 183 (114933). [PMID:] [10.1016/j.lwt.2023.114933]
2. Peng Weichao, Yan Shuaihu, Zhou Ke, Wu Hai-Chen, Liu Lei, Zhao Yuliang. (2023) High-resolution discrimination of homologous and isomeric proteinogenic amino acids in nanopore sensors with ultrashort single-walled carbon nanotubes. Nature Communications, 14 (1): (1-8). [PMID:37160961] [10.1038/s41467-023-38399-4]
3. Sheng Liu, Bo Yang, Yingxiang Hou, Kaige Cui, Xiaozhu Yang, Xiaoxiong Li, Lianwan Chen, Shichao Liu, Zhichao Zhang, Yuanyuan Jia, Yufeng Xie, Ying Xue, Xiaomei Li, Bingxue Yan, Changxin Wu, Wen Deng, Jianxun Qi, Defen Lu, George F. Gao, Peiyi Wang, Guijun Shang. (2023) The mechanism of STING autoinhibition and activation. MOLECULAR CELL, 83 (1502-1518.e10). [PMID:37086726] [10.1016/j.molcel.2023.03.029]
4. Qin Guo, Jie Cai, Pengyu Li, Dongling Xu, Xiaomin Ni, Hui Wen, Dan Liu, Suizhen Lin, Haiyan Hu. (2023) Comparison of bile salt/phosphatidylcholine mixed micelles in solubilization to sterols and stability. Drug Design Development and Therapy, [PMID:27895469] [10.2147/DDDT.S119918]
5. Chuntian Shao, Jingwei Zhong, Junwen Liu, Yiyan Yang, Meilin Li, Yang Yu, Yaqin Xu, Libo Wang. (2023) Preparation, characterization and bioactivities of selenized polysaccharides from Lonicera caerulea L. fruits. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 225 (484). [PMID:36403769] [10.1016/j.ijbiomac.2022.11.105]
6. Shuo Qi, Xiaoze Dong, Yuhan Sun, Yin Zhang, Nuo Duan, Zhouping Wang. (2022) Split aptamer remodeling-initiated target-self-service 3D-DNA walker for ultrasensitive detection of 17β-estradiol. JOURNAL OF HAZARDOUS MATERIALS, 439 (129590). [PMID:35872451] [10.1016/j.jhazmat.2022.129590]
7. Ping Li, Yiting Yang, Zijin Lin, Shijin Hong, Ling Jiang, Han Zhou, Lu Yang, Liang Zhu, Xiaodong Liu, Li Liu. (2022) Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood–Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (14): (7666). [PMID:35887010] [10.3390/ijms23147666]
8. Wang Cong-Yu, Sun Min, Fan Zhen, Du Jian-Zhong. (2022) Intestine Enzyme-responsive Polysaccharide-based Hydrogel to Open Epithelial Tight Junctions for Oral Delivery of Imatinib against Colon Cancer. CHINESE JOURNAL OF POLYMER SCIENCE, 40 (10): (1154-1164). [PMID:] [10.1007/s10118-022-2726-0]
9. Chu-tong Tian, Jing-jing Guo, Yi-fan Miao, He-lin Wang, Qing Ye, Chun-lin Guo, Ming-yang Zhang, Zhong-gui He, Jin Sun. (2022) Long chain triglyceride-lipid formulation promotes the oral absorption of the lipidic prodrugs through coincident intestinal behaviors. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 176 (122). [PMID:35643367] [10.1016/j.ejpb.2022.05.015]
10. Zhang Pengpeng, Zhang Miaomiao, Dong Kaiyu, Zhang Yicong, Yang Shuang, Wang Yuanhong, Jiang Tingfu, Yu Mingming, Lv Zhihua. (2022) Evaluation of Chito-Oligosaccharide (COS) in Vitro and in Vivo: Permeability Characterization in Caco-2 Cells Monolayer and Pharmacokinetics Properties in Rats. Journal of Ocean University of China, 21 (3): (782-788). [PMID:] [10.1007/s11802-022-5088-x]
11. Yu Luo, Shenyu Huang, Lie Ma. (2021) A novel detergent-based decellularization combined with carbodiimide crosslinking for improving anti-calcification of bioprosthetic heart valve. Biomedical Materials, 16 (4): (45022). [PMID:33979785] [10.1088/1748-605X/ac0088]
12. Yang Min, Lu Xiaoluan, Tang Luyang, Fu Yangyang, Yang Peixin. (2020) Thermosensitive nanocomposite gel loaded zinc phthalocyanine for photodynamic therapy. JOURNAL OF POLYMER RESEARCH, 27 (9): (1-10). [PMID:] [10.1007/s10965-020-02253-8]
13. Xinrui Li, Jing Su, Zul Kamal, Pengcheng Guo, Xinyi Wu, Lina Lu, Hongbing Wu, Mingfeng Qiu. (2020) Odorranalectin modified PEG–PLGA/PEG–PBLG curcumin-loaded nanoparticle for intranasal administration. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 46 (6): (899-909). [PMID:32375569] [10.1080/03639045.2020.1762202]
14. Zhou Xueqing, Xie Yanli, Zhao Zhendong, Fu Wenyan. (2020) A simple strategy based on fibers coated with surfactant-functionalized multiwalled carbon nanotubes to improve the properties of solid-phase microextraction of phenols in aqueous solution. BMC Chemistry, 14 (1): (1-11). [PMID:32099973] [10.1186/s13065-020-00665-7]
15. Xuejuan Zhang, Xiao Yue, Yingtong Cui, Ziyu Zhao, Ying Huang, Shihao Cai, Guanlin Wang, Wenhao Wang, Smyth Hugh, Xin Pan, Chuanbin Wu, Wen Tan. (2020) A Systematic Safety Evaluation of Nanoporous Mannitol Material as a Dry-Powder Inhalation Carrier System. JOURNAL OF PHARMACEUTICAL SCIENCES, 109 (1692). [PMID:31987851] [10.1016/j.xphs.2020.01.017]
16. Xiaoluan Lu, Wentao Zhu, Tingyu Chen, Qianrong Peng, Changmu Yu, Min Yang. (2019) Exploration of photophysical and photochemical properties of Zinc phthalocyanine-loaded SDC/TPGS mixed micelles. CHEMICAL PHYSICS LETTERS, 735 (136737). [PMID:] [10.1016/j.cplett.2019.136737]
17. Xu Yingxin, Fang Tianxu, Yang Yifan, Sun Li’ang, Shen Qi. (2019) Preparation of Deoxycholate-Modified Docetaxel-Cimetidine Complex Chitosan Nanoparticles to Improve Oral Bioavailability. AAPS PHARMSCITECH, 20 (7): (1-10). [PMID:31489504] [10.1208/s12249-019-1520-y]
18. Hailing Yang, Zhenjie Liu, Yonglong Song, Changjiang Hu. (2019) Hyaluronic acid-functionalized bilosomes for targeted delivery of tripterine to inflamed area with enhancive therapy on arthritis. DRUG DELIVERY, 26 (1): (820-830). [PMID:31389248] [10.1080/10717544.2019.1636423]
19. Hui Li, Yang Pang, Xin Wang, Xun Cao, Xun He, Kequan Chen, Ganlu Li, Pingkai Ouyang, Weiming Tan. (2019) Phospholipase D encapsulated into metal-surfactant nanocapsules for enhancing biocatalysis in a two-phase system. RSC Advances, 9 (12): (6548-6555). [PMID:35518461] [10.1039/C8RA09827A]
20. Hui Li, Yan Ni, Xun Cao, Xun He, Ganlu Li, Kequan Chen, Pingkai Ouyang, Jianming Yang, Weiming Tan. (2019) Highly active nanobiocatalysis in deep eutectic solvents via metal-driven enzyme-surfactant nanocomposite. JOURNAL OF BIOTECHNOLOGY, 292 (39). [PMID:30690095] [10.1016/j.jbiotec.2019.01.010]
21. Li Zhang, Dandan Ren, Jianyu Zhou, Guangneng Peng, Gang Shu, Zhixiang Yuan, Fei Shi, Ling Zhao, Lizi Yin, Guoqing Fan, Chang Liu, Hualin Fu. (2018) Toltrazuril mixed nanomicelle delivery system based on sodium deoxycholate–Brij C20 polyethylene ether–triton x100: Characterization, solubility, and bioavailability study. COLLOIDS AND SURFACES B-BIOINTERFACES, 163 (125). [PMID:29289823] [10.1016/j.colsurfb.2017.12.018]
22. Weihua Jiang, Ju Wang, Lei Yang, Xuewei Jiang, Zhaoshi Bai, Zheran Wang, Yunpeng He, Dongkai Wang. (2015) Nanostructured lipid carriers modified with PEGylated carboxymethylcellulose polymers for effective delivery of docetaxel. RSC Advances, 5 (110): (90386-90395). [PMID:] [10.1039/C5RA13642C]
23. Xuesong Kong, Shixiang Feng, Xu Zhang, Yan Li. (2014) Effects of bile salts and divalent cations on the adsorption of norfloxacin by agricultural soils. Journal of Environmental Sciences, 26 (846). [PMID:25079415] [10.1016/S1001-0742(13)60480-5]
24. Ni Li, Li-Hua Peng, Xi Chen, Shinsaku Nakagawa, Jian-Qing Gao. (2011) Effective transcutaneous immunization by antigen-loaded flexible liposome in vivo. International Journal of Nanomedicine, 6 ( 3241–3250). [PMID:22228992] [10.2147/IJN.S26152]

References

1. Jing Zhang, Kairu Liu, Xiaojuan Duan, Xuhao Wang, Wupeng Ge, Wenping Jin. (2023) Restoration of Choujiu Koji and evaluation of its brewing performance. LWT-FOOD SCIENCE AND TECHNOLOGY, 183 (114933). [PMID:] [10.1016/j.lwt.2023.114933]
2. Peng Weichao, Yan Shuaihu, Zhou Ke, Wu Hai-Chen, Liu Lei, Zhao Yuliang. (2023) High-resolution discrimination of homologous and isomeric proteinogenic amino acids in nanopore sensors with ultrashort single-walled carbon nanotubes. Nature Communications, 14 (1): (1-8). [PMID:37160961] [10.1038/s41467-023-38399-4]
3. Sheng Liu, Bo Yang, Yingxiang Hou, Kaige Cui, Xiaozhu Yang, Xiaoxiong Li, Lianwan Chen, Shichao Liu, Zhichao Zhang, Yuanyuan Jia, Yufeng Xie, Ying Xue, Xiaomei Li, Bingxue Yan, Changxin Wu, Wen Deng, Jianxun Qi, Defen Lu, George F. Gao, Peiyi Wang, Guijun Shang. (2023) The mechanism of STING autoinhibition and activation. MOLECULAR CELL, 83 (1502-1518.e10). [PMID:37086726] [10.1016/j.molcel.2023.03.029]
4. Qin Guo, Jie Cai, Pengyu Li, Dongling Xu, Xiaomin Ni, Hui Wen, Dan Liu, Suizhen Lin, Haiyan Hu. (2023) Comparison of bile salt/phosphatidylcholine mixed micelles in solubilization to sterols and stability. Drug Design Development and Therapy, [PMID:27895469] [10.2147/DDDT.S119918]
5. Chuntian Shao, Jingwei Zhong, Junwen Liu, Yiyan Yang, Meilin Li, Yang Yu, Yaqin Xu, Libo Wang. (2023) Preparation, characterization and bioactivities of selenized polysaccharides from Lonicera caerulea L. fruits. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 225 (484). [PMID:36403769] [10.1016/j.ijbiomac.2022.11.105]
6. Shuo Qi, Xiaoze Dong, Yuhan Sun, Yin Zhang, Nuo Duan, Zhouping Wang. (2022) Split aptamer remodeling-initiated target-self-service 3D-DNA walker for ultrasensitive detection of 17β-estradiol. JOURNAL OF HAZARDOUS MATERIALS, 439 (129590). [PMID:35872451] [10.1016/j.jhazmat.2022.129590]
7. Ping Li, Yiting Yang, Zijin Lin, Shijin Hong, Ling Jiang, Han Zhou, Lu Yang, Liang Zhu, Xiaodong Liu, Li Liu. (2022) Bile Duct Ligation Impairs Function and Expression of Mrp1 at Rat Blood–Retinal Barrier via Bilirubin-Induced P38 MAPK Pathway Activations. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (14): (7666). [PMID:35887010] [10.3390/ijms23147666]
8. Wang Cong-Yu, Sun Min, Fan Zhen, Du Jian-Zhong. (2022) Intestine Enzyme-responsive Polysaccharide-based Hydrogel to Open Epithelial Tight Junctions for Oral Delivery of Imatinib against Colon Cancer. CHINESE JOURNAL OF POLYMER SCIENCE, 40 (10): (1154-1164). [PMID:] [10.1007/s10118-022-2726-0]
9. Chu-tong Tian, Jing-jing Guo, Yi-fan Miao, He-lin Wang, Qing Ye, Chun-lin Guo, Ming-yang Zhang, Zhong-gui He, Jin Sun. (2022) Long chain triglyceride-lipid formulation promotes the oral absorption of the lipidic prodrugs through coincident intestinal behaviors. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 176 (122). [PMID:35643367] [10.1016/j.ejpb.2022.05.015]
10. Zhang Pengpeng, Zhang Miaomiao, Dong Kaiyu, Zhang Yicong, Yang Shuang, Wang Yuanhong, Jiang Tingfu, Yu Mingming, Lv Zhihua. (2022) Evaluation of Chito-Oligosaccharide (COS) in Vitro and in Vivo: Permeability Characterization in Caco-2 Cells Monolayer and Pharmacokinetics Properties in Rats. Journal of Ocean University of China, 21 (3): (782-788). [PMID:] [10.1007/s11802-022-5088-x]
11. Yu Luo, Shenyu Huang, Lie Ma. (2021) A novel detergent-based decellularization combined with carbodiimide crosslinking for improving anti-calcification of bioprosthetic heart valve. Biomedical Materials, 16 (4): (45022). [PMID:33979785] [10.1088/1748-605X/ac0088]
12. Yang Min, Lu Xiaoluan, Tang Luyang, Fu Yangyang, Yang Peixin. (2020) Thermosensitive nanocomposite gel loaded zinc phthalocyanine for photodynamic therapy. JOURNAL OF POLYMER RESEARCH, 27 (9): (1-10). [PMID:] [10.1007/s10965-020-02253-8]
13. Xinrui Li, Jing Su, Zul Kamal, Pengcheng Guo, Xinyi Wu, Lina Lu, Hongbing Wu, Mingfeng Qiu. (2020) Odorranalectin modified PEG–PLGA/PEG–PBLG curcumin-loaded nanoparticle for intranasal administration. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 46 (6): (899-909). [PMID:32375569] [10.1080/03639045.2020.1762202]
14. Zhou Xueqing, Xie Yanli, Zhao Zhendong, Fu Wenyan. (2020) A simple strategy based on fibers coated with surfactant-functionalized multiwalled carbon nanotubes to improve the properties of solid-phase microextraction of phenols in aqueous solution. BMC Chemistry, 14 (1): (1-11). [PMID:32099973] [10.1186/s13065-020-00665-7]
15. Xuejuan Zhang, Xiao Yue, Yingtong Cui, Ziyu Zhao, Ying Huang, Shihao Cai, Guanlin Wang, Wenhao Wang, Smyth Hugh, Xin Pan, Chuanbin Wu, Wen Tan. (2020) A Systematic Safety Evaluation of Nanoporous Mannitol Material as a Dry-Powder Inhalation Carrier System. JOURNAL OF PHARMACEUTICAL SCIENCES, 109 (1692). [PMID:31987851] [10.1016/j.xphs.2020.01.017]
16. Xiaoluan Lu, Wentao Zhu, Tingyu Chen, Qianrong Peng, Changmu Yu, Min Yang. (2019) Exploration of photophysical and photochemical properties of Zinc phthalocyanine-loaded SDC/TPGS mixed micelles. CHEMICAL PHYSICS LETTERS, 735 (136737). [PMID:] [10.1016/j.cplett.2019.136737]
17. Xu Yingxin, Fang Tianxu, Yang Yifan, Sun Li’ang, Shen Qi. (2019) Preparation of Deoxycholate-Modified Docetaxel-Cimetidine Complex Chitosan Nanoparticles to Improve Oral Bioavailability. AAPS PHARMSCITECH, 20 (7): (1-10). [PMID:31489504] [10.1208/s12249-019-1520-y]
18. Hailing Yang, Zhenjie Liu, Yonglong Song, Changjiang Hu. (2019) Hyaluronic acid-functionalized bilosomes for targeted delivery of tripterine to inflamed area with enhancive therapy on arthritis. DRUG DELIVERY, 26 (1): (820-830). [PMID:31389248] [10.1080/10717544.2019.1636423]
19. Hui Li, Yang Pang, Xin Wang, Xun Cao, Xun He, Kequan Chen, Ganlu Li, Pingkai Ouyang, Weiming Tan. (2019) Phospholipase D encapsulated into metal-surfactant nanocapsules for enhancing biocatalysis in a two-phase system. RSC Advances, 9 (12): (6548-6555). [PMID:35518461] [10.1039/C8RA09827A]
20. Hui Li, Yan Ni, Xun Cao, Xun He, Ganlu Li, Kequan Chen, Pingkai Ouyang, Jianming Yang, Weiming Tan. (2019) Highly active nanobiocatalysis in deep eutectic solvents via metal-driven enzyme-surfactant nanocomposite. JOURNAL OF BIOTECHNOLOGY, 292 (39). [PMID:30690095] [10.1016/j.jbiotec.2019.01.010]
21. Li Zhang, Dandan Ren, Jianyu Zhou, Guangneng Peng, Gang Shu, Zhixiang Yuan, Fei Shi, Ling Zhao, Lizi Yin, Guoqing Fan, Chang Liu, Hualin Fu. (2018) Toltrazuril mixed nanomicelle delivery system based on sodium deoxycholate–Brij C20 polyethylene ether–triton x100: Characterization, solubility, and bioavailability study. COLLOIDS AND SURFACES B-BIOINTERFACES, 163 (125). [PMID:29289823] [10.1016/j.colsurfb.2017.12.018]
22. Weihua Jiang, Ju Wang, Lei Yang, Xuewei Jiang, Zhaoshi Bai, Zheran Wang, Yunpeng He, Dongkai Wang. (2015) Nanostructured lipid carriers modified with PEGylated carboxymethylcellulose polymers for effective delivery of docetaxel. RSC Advances, 5 (110): (90386-90395). [PMID:] [10.1039/C5RA13642C]
23. Xuesong Kong, Shixiang Feng, Xu Zhang, Yan Li. (2014) Effects of bile salts and divalent cations on the adsorption of norfloxacin by agricultural soils. Journal of Environmental Sciences, 26 (846). [PMID:25079415] [10.1016/S1001-0742(13)60480-5]
24. Ni Li, Li-Hua Peng, Xi Chen, Shinsaku Nakagawa, Jian-Qing Gao. (2011) Effective transcutaneous immunization by antigen-loaded flexible liposome in vivo. International Journal of Nanomedicine, 6 ( 3241–3250). [PMID:22228992] [10.2147/IJN.S26152]

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