Basic Description

Synonyms	Sodium dithionite \| SODIUM HYDROSULFITE \| 7775-14-6 \| Sodium hydrosulphite \| Vatrolite \| Sodium sulfoxylate \| Disodium dithionite \| Dithionous acid, disodium salt \| Blankit \| Burmol \| Hydros \| Blankit IN \| Sodium hypodisulfite \| V-Brite B \| Hydrosulfite R Conc \| Disodium hydrosulfite \|
Specifications & Purity	≥59%
Storage Temp	Argon charged
Shipped In	Normal
Product Description	Product introduction: It has a slight special smell. Sensitive to light. There are anhydrous and dihydrate crystalline forms in the solid state. The dihydrate crystal is unstable and can be dehydrated when it is gradually heated to a certain temperature in alkaline medium, and it can be transformed into anhydrous crystal, which is easy to decompose. Generally, it is more stable in alkaline medium than in neutral medium, and it is more stable when dry than when wet. Moisture, heat or exposure to air can accelerate its decomposition and even combustion. During decomposition, sulfur dioxide and a large amount of heat are released, and it can spontaneously ignite at 250 ℃. In the presence of moisture or in aqueous solution, sodium bisulfite and sodium bisulfite are quickly formed and are acidic. It is easily soluble in water and slightly soluble in ethanol. The aqueous solution is neutral. It is easy to burn when wet. Due to its unstable nature, a certain amount of stabilizer is added to the finished product.

Associated Targets(Human)

Associated Targets(non-human)

Candida albicans 78123 Activities

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Leishmania mexicana 936 Activities

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

INCHI	InChI=1S/2Na.H2O4S2/c;;1-5(2)6(3)4/h;;(H,1,2)(H,3,4)/q2*+1;/p-2
InChi Key	JVBXVOWTABLYPX-UHFFFAOYSA-L
Canonical SMILES	[O-]S(=O)S(=O)[O-].[Na+].[Na+]
Isomeric SMILES	[O-]S(=O)S(=O)[O-].[Na+].[Na+]
PubChem CID	24489
UN Number	1384
Packing Group	II
Molecular Weight	174.11

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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10 results found

Lot Number	Certificate Type	Date	Item
C2422303	Certificate of Analysis	Mar 30, 2024	S492246
A2403250	Certificate of Analysis	Jan 05, 2024	S492246
G23041108	Certificate of Analysis	Jul 11, 2023	S492246
D23201136	Certificate of Analysis	Apr 27, 2023	S492246
B2308352	Certificate of Analysis	Feb 10, 2023	S492246
A2330449	Certificate of Analysis	Feb 06, 2023	S492246
L2214064	Certificate of Analysis	Dec 21, 2022	S492246
C2303201	Certificate of Analysis	Nov 14, 2022	S492246
K2210145	Certificate of Analysis	Nov 14, 2022	S492246
K2210146	Certificate of Analysis	Nov 14, 2022	S492246

Chemical and Physical Properties

Solubility	Soluble in water. Slightly soluble in alcohol.
Sensitivity	Air sensitive；Moisture sensitive
Melt Point(°C)	300°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07, GHS02
Signal	Danger
Hazard Statements	H319:Causes serious eye irritation H302:Harmful if swallowed H402:Harmful to aquatic life H251:Self-heating; may catch fire
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P270:Do not eat, drink or smoke when using this product. P337+P313:IF eye irritation persists: Get medical advice/attention. P330:Rinse mouth. P235+P410:Keep cool. Protect from sunlight. P301+P312+P330:IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.
Class	4.2

Citations of This Product

1. Yonghong Fan, Juan Pei, Yinhua Qin, Huifang Du, Xiaohang Qu, Wenya Li, Boyue Huang, Ju Tan, Yong Liu, Gang Li, Ming Ke, Youqian Xu, Chuhong Zhu. (2024) Construction of tissue-engineered vascular grafts with enhanced patency by integrating heparin, cell-adhesive peptide, and carbon monoxide nanogenerators into acellular blood vessels. Bioactive Materials, 34 (221). [PMID:38235307]
2. Xuefang Zhao, Hui Xu, Minzhang Chen, Yong Chen, Xiuqing Kong. (2024) Enhancement of norfloxacin degradation by citrate in S-nZVI@Ps system: Chelation and FeS layer. ENVIRONMENTAL RESEARCH, 245 (117981). [PMID:38142729]
3. Junkai Jiang, Jialiang Xie, Liang Zhou, Wei Han, Jing Ye, Daorun Hu, Weichang Xie, Jianbin Qiu, Runfu Chen, Xiaolei Wang. (2023) Near infrared responsive nitric oxide and carbon monoxide nanoplatform for synergistic photodynamic therapy against periodontitis. CHEMICAL ENGINEERING JOURNAL, (21): (147850). [PMID:26134560]
4. Chen Zhao, Hongmei Xu, Yating Meng, Yu Wang, Shaomin Shuang, Chuan Dong. (2023) Anthraquinone-based Schiff base fluorescent probe for the sequential sensing of Al3+ and pyrophosphate in a near-perfect aqueous solution and bioimaging. JOURNAL OF MOLECULAR LIQUIDS, 391 (15): (123326). [PMID:15922294]
5. Hailan Wang, Lingna Wang, Enchao Li, Ruobin Dai, Zhiwei Wang. (2023) Efficacies and mechanisms of different cleaning strategies for NF and RO membranes in a full-scale zero liquid discharge system. Journal of Water Process Engineering, 56 (6): (104308). [PMID:22155786]
6. Peicheng Huang, Weichun Yang, Qingzhu Li, Qi Liao, Mengying Si, Meiqing Shi, Zhihui Yang. (2023) A novel slow-release selenium approach for cadmium reduction and selenium enrichment in rice (Oryza sativa L.). CHEMOSPHERE, 342 (20): (140183). [PMID:37726061]
7. Dongdong Wang, Mu Li, Hanning Zhang, Congshu Feng, Lili Wu, Lesan Yan. (2023) A Novel Redox-Sensitive Drug Delivery System Based on Trimethyl-Locked Polycarbonate. BIOMACROMOLECULES, 24 (9): (4303–4315). [PMID:37585690]
8. Xin Jin, Zelin Ou, Guowei Zhang, Rong Shi, Jumin Yang, Wenguang Liu, Gaoxing Luo, Jun Deng, Wei Wang. (2023) A CO-mediated photothermal therapy to kill drug-resistant bacteria and minimize thermal injury for infected diabetic wound healing. Biomaterials Science, [PMID:37531204]
9. Ye Ru-Yi, Song Juan, Zhang Zhi-Jun, Yu Hui-Lei. (2023) Prokaryotic expression and characterization of artificial self-sufficient CYP120A monooxygenases. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 107 (18): (5727-5737). [PMID:37477695]
10. Jinhai Xie, Shuangyu Tian, Hanning Zhang, Congshu Feng, Yingchao Han, Honglian Dai, Lesan Yan. (2023) A Novel NQO1 Enzyme-Responsive Polyurethane Nanocarrier for Redox-Triggered Intracellular Drug Release. BIOMACROMOLECULES, 24 (5): (2225–2236). [PMID:37040694]
11. Wenfu Ma, Xuhui Liu, Minhui Yang, Qingxiang Hong, Lingjie Meng, Qiuyang Zhang, Jie Chen, Changjiang Pan. (2023) Fabrication of CO-releasing surface to enhance the blood compatibility and endothelialization of TiO2 nanotubes on titanium surface. Biomaterials Advances, 149 (213393). [PMID:36966654]
12. Di Zhang, Hao Tang, Bing Zhao, Lijie Liu, Hongwei Pang, Xiangxue Wang, Shujun Yu. (2023) Immobilization of uranium by S-NZVI and UiO-66-NO2 composite through combined adsorption and reduction. Journal of Cleaner Production, 390 (136149). [PMID:]
13. Lili Qian, Qian Li, Zhenshan Ding, Kejun Luo, Jiamin Su, Jiawei Chen, Guangying Zhu, Zhihua Gan, Qingsong Yu. (2022) Prodrug Nanosensitizer Overcomes the Radiation Resistance of Hypoxic Tumor. ACS Applied Materials & Interfaces, 14 (51): (56454–56470). [PMID:36525559]
14. Haoran Tian, Chao Huang, Ping Wang, Jie Wei, Xinyan Li, Ruimei Zhang, Dingxun Ling, Chongling Feng, Hao Liu, Mengxin Wang, Zhiming Liu. (2023) Enhanced elimination of Cr(VI) from aqueous media by polyethyleneimine modified corn straw biochar supported sulfide nanoscale zero valent iron: Performance and mechanism. BIORESOURCE TECHNOLOGY, 369 (128452). [PMID:36503100]
15. Wenwen Zhang, Xiaodong Li, Jialun Shen, Zongquan Sun, Xuefei Zhou, Fasheng Li, Fujun Ma, Qingbao Gu. (2023) Insights into the degradation process of phenol during in-situ thermal desorption: The overlooked oxidation of hydroxyl radicals from oxygenation of reduced Fe-bearing clay minerals. JOURNAL OF HAZARDOUS MATERIALS, 444 (130401). [PMID:36403451]
16. Wanying Xie, Wei Song, Ji Li, Xiaolei Zhang, Wenyi Dong, Feiyun Sun. (2023) Micro-polluted water resources treatment by PVDF-TiO2 membrane combined with Fe2+/sodium dithionite (DTN)/O2 pre-oxidation process. CHEMOSPHERE, 311 (136998). [PMID:36309061]
17. Yin Li, Jiahui Hu, Yubin Zou, Lin Lin, Hebin Liang, Huaxin Lei, Bing Li, Xiao-yan Li. (2023) Catalytic activity enhancement by P and S co-doping of a single-atom Fe catalyst for peroxymonosulfate-based oxidation. CHEMICAL ENGINEERING JOURNAL, 453 (139890). [PMID:]
18. Xiaoran Zhu, Jianze Zhang, Yan Wang, Mingsheng Yang, Haiping Yu, Tengfei Li, Mingjun Hu, Jun Yang. (2022) Achieving High-Performance Oxygen Reduction Catalyst and Zn–Air Battery through a Synergistic Nitrogen Doping Strategy. Energy Technology, 10 (11): (2200602). [PMID:]
19. Zhuoyue Wang, Wei Song, Ji Li, Xiaolei Zhang, Hongjie Wang. (2022) Optimization and mechanism of Tetrabromobisphenol A removal by dithionite under anaerobic conditions: Response surface methodology and degradation pathway. JOURNAL OF ENVIRONMENTAL MANAGEMENT, 321 (116034). [PMID:36027733]
20. Kai Sun, Jiaying Yu, Jinzhong Hu, Jian Chen, Jia Song, Zhixin Chen, Zhuoer Cai, Zhuoxuan Lu, Liming Zhang, Zhifei Wang. (2022) Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment. Acta Biomaterialia, 148 (230). [PMID:35724919]
21. Nan Wang, Hui Sun, Xiaodong Yang, Wenbo Lin, Wenyu He, Hao Liu, Gajanan Bhat, Bin Yu. (2022) Flexible temperature sensor based on RGO/CNTs@PBT melting blown nonwoven fabric. SENSORS AND ACTUATORS A-PHYSICAL, 339 (113519). [PMID:]
22. Weijuan Zou, Longchen Wang, Junnian Hao, Lixian Jiang, Wenxian Du, Tao Ying, Xiaojun Cai, Haitao Ran, Jianrong Wu, Yuanyi Zheng. (2022) Phase-change cascaded nanomedicine for intensive photothermal-enhanced nanocatalytic therapy via tumor oxidative stress amplification. COMPOSITES PART B-ENGINEERING, 234 (109707). [PMID:]
23. Hongwei Pang, Enyao Zhang, Di Zhang, Xiangxue Wang, Bing Zhao, Lijie Liu, Xiaoying Ma, Gang Song, Shujun Yu. (2022) Precursor impact and mechanism analysis of uranium elimination by biochar supported sulfurized nanoscale zero-valent iron. Journal of Environmental Chemical Engineering, 10 (107288). [PMID:]
24. Xue Liu, Zhenfeng Wu, Chunjing Guo, Huimin Guo, Yanguo Su, Qiang Chen, Changgang Sun, Qingming Liu, Daquan Chen, Hongjie Mu. (2022) Hypoxia responsive nano-drug delivery system based on angelica polysaccharide for liver cancer therapy. DRUG DELIVERY, 29 (1): (138-148). [PMID:34967268]
25. Wei Song, Ji Li, Caixia Fu, Zhuoyue Wang, Zhihong Wang, Qiao Wang, Xiaolei Zhang, Yuxin Zhou, Xing Du. (2022) Low consumption and portable technology for dithionite detection based on potassium ferricyanide differential spectrophotometry method in related advanced oxidation processes. ENVIRONMENTAL RESEARCH, 205 (112430). [PMID:34843722]
26. Yue-Cai Yin,Hui-Lei Yu,Zheng-Jiao Luan,Ren-Jie Li,Peng-Fei Ouyang,Jing Liu,Jian-He Xu. (2014-09-23) Unusually broad substrate profile of self-sufficient cytochrome P450 monooxygenase CYP116B4 from Labrenzia aggregata.. Chembiochem : a European journal of chemical biology, 15 ((16)): (2443-2449). [PMID:25236924]

References

1. Yonghong Fan, Juan Pei, Yinhua Qin, Huifang Du, Xiaohang Qu, Wenya Li, Boyue Huang, Ju Tan, Yong Liu, Gang Li, Ming Ke, Youqian Xu, Chuhong Zhu. (2024) Construction of tissue-engineered vascular grafts with enhanced patency by integrating heparin, cell-adhesive peptide, and carbon monoxide nanogenerators into acellular blood vessels. Bioactive Materials, 34 (221). [PMID:38235307]
2. Xuefang Zhao, Hui Xu, Minzhang Chen, Yong Chen, Xiuqing Kong. (2024) Enhancement of norfloxacin degradation by citrate in S-nZVI@Ps system: Chelation and FeS layer. ENVIRONMENTAL RESEARCH, 245 (117981). [PMID:38142729]
3. Junkai Jiang, Jialiang Xie, Liang Zhou, Wei Han, Jing Ye, Daorun Hu, Weichang Xie, Jianbin Qiu, Runfu Chen, Xiaolei Wang. (2023) Near infrared responsive nitric oxide and carbon monoxide nanoplatform for synergistic photodynamic therapy against periodontitis. CHEMICAL ENGINEERING JOURNAL, (21): (147850). [PMID:26134560]
4. Chen Zhao, Hongmei Xu, Yating Meng, Yu Wang, Shaomin Shuang, Chuan Dong. (2023) Anthraquinone-based Schiff base fluorescent probe for the sequential sensing of Al3+ and pyrophosphate in a near-perfect aqueous solution and bioimaging. JOURNAL OF MOLECULAR LIQUIDS, 391 (15): (123326). [PMID:15922294]
5. Hailan Wang, Lingna Wang, Enchao Li, Ruobin Dai, Zhiwei Wang. (2023) Efficacies and mechanisms of different cleaning strategies for NF and RO membranes in a full-scale zero liquid discharge system. Journal of Water Process Engineering, 56 (6): (104308). [PMID:22155786]
6. Peicheng Huang, Weichun Yang, Qingzhu Li, Qi Liao, Mengying Si, Meiqing Shi, Zhihui Yang. (2023) A novel slow-release selenium approach for cadmium reduction and selenium enrichment in rice (Oryza sativa L.). CHEMOSPHERE, 342 (20): (140183). [PMID:37726061]
7. Dongdong Wang, Mu Li, Hanning Zhang, Congshu Feng, Lili Wu, Lesan Yan. (2023) A Novel Redox-Sensitive Drug Delivery System Based on Trimethyl-Locked Polycarbonate. BIOMACROMOLECULES, 24 (9): (4303–4315). [PMID:37585690]
8. Xin Jin, Zelin Ou, Guowei Zhang, Rong Shi, Jumin Yang, Wenguang Liu, Gaoxing Luo, Jun Deng, Wei Wang. (2023) A CO-mediated photothermal therapy to kill drug-resistant bacteria and minimize thermal injury for infected diabetic wound healing. Biomaterials Science, [PMID:37531204]
9. Ye Ru-Yi, Song Juan, Zhang Zhi-Jun, Yu Hui-Lei. (2023) Prokaryotic expression and characterization of artificial self-sufficient CYP120A monooxygenases. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 107 (18): (5727-5737). [PMID:37477695]
10. Jinhai Xie, Shuangyu Tian, Hanning Zhang, Congshu Feng, Yingchao Han, Honglian Dai, Lesan Yan. (2023) A Novel NQO1 Enzyme-Responsive Polyurethane Nanocarrier for Redox-Triggered Intracellular Drug Release. BIOMACROMOLECULES, 24 (5): (2225–2236). [PMID:37040694]
11. Wenfu Ma, Xuhui Liu, Minhui Yang, Qingxiang Hong, Lingjie Meng, Qiuyang Zhang, Jie Chen, Changjiang Pan. (2023) Fabrication of CO-releasing surface to enhance the blood compatibility and endothelialization of TiO2 nanotubes on titanium surface. Biomaterials Advances, 149 (213393). [PMID:36966654]
12. Di Zhang, Hao Tang, Bing Zhao, Lijie Liu, Hongwei Pang, Xiangxue Wang, Shujun Yu. (2023) Immobilization of uranium by S-NZVI and UiO-66-NO2 composite through combined adsorption and reduction. Journal of Cleaner Production, 390 (136149). [PMID:]
13. Lili Qian, Qian Li, Zhenshan Ding, Kejun Luo, Jiamin Su, Jiawei Chen, Guangying Zhu, Zhihua Gan, Qingsong Yu. (2022) Prodrug Nanosensitizer Overcomes the Radiation Resistance of Hypoxic Tumor. ACS Applied Materials & Interfaces, 14 (51): (56454–56470). [PMID:36525559]
14. Haoran Tian, Chao Huang, Ping Wang, Jie Wei, Xinyan Li, Ruimei Zhang, Dingxun Ling, Chongling Feng, Hao Liu, Mengxin Wang, Zhiming Liu. (2023) Enhanced elimination of Cr(VI) from aqueous media by polyethyleneimine modified corn straw biochar supported sulfide nanoscale zero valent iron: Performance and mechanism. BIORESOURCE TECHNOLOGY, 369 (128452). [PMID:36503100]
15. Wenwen Zhang, Xiaodong Li, Jialun Shen, Zongquan Sun, Xuefei Zhou, Fasheng Li, Fujun Ma, Qingbao Gu. (2023) Insights into the degradation process of phenol during in-situ thermal desorption: The overlooked oxidation of hydroxyl radicals from oxygenation of reduced Fe-bearing clay minerals. JOURNAL OF HAZARDOUS MATERIALS, 444 (130401). [PMID:36403451]
16. Wanying Xie, Wei Song, Ji Li, Xiaolei Zhang, Wenyi Dong, Feiyun Sun. (2023) Micro-polluted water resources treatment by PVDF-TiO2 membrane combined with Fe2+/sodium dithionite (DTN)/O2 pre-oxidation process. CHEMOSPHERE, 311 (136998). [PMID:36309061]
17. Yin Li, Jiahui Hu, Yubin Zou, Lin Lin, Hebin Liang, Huaxin Lei, Bing Li, Xiao-yan Li. (2023) Catalytic activity enhancement by P and S co-doping of a single-atom Fe catalyst for peroxymonosulfate-based oxidation. CHEMICAL ENGINEERING JOURNAL, 453 (139890). [PMID:]
18. Xiaoran Zhu, Jianze Zhang, Yan Wang, Mingsheng Yang, Haiping Yu, Tengfei Li, Mingjun Hu, Jun Yang. (2022) Achieving High-Performance Oxygen Reduction Catalyst and Zn–Air Battery through a Synergistic Nitrogen Doping Strategy. Energy Technology, 10 (11): (2200602). [PMID:]
19. Zhuoyue Wang, Wei Song, Ji Li, Xiaolei Zhang, Hongjie Wang. (2022) Optimization and mechanism of Tetrabromobisphenol A removal by dithionite under anaerobic conditions: Response surface methodology and degradation pathway. JOURNAL OF ENVIRONMENTAL MANAGEMENT, 321 (116034). [PMID:36027733]
20. Kai Sun, Jiaying Yu, Jinzhong Hu, Jian Chen, Jia Song, Zhixin Chen, Zhuoer Cai, Zhuoxuan Lu, Liming Zhang, Zhifei Wang. (2022) Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment. Acta Biomaterialia, 148 (230). [PMID:35724919]
21. Nan Wang, Hui Sun, Xiaodong Yang, Wenbo Lin, Wenyu He, Hao Liu, Gajanan Bhat, Bin Yu. (2022) Flexible temperature sensor based on RGO/CNTs@PBT melting blown nonwoven fabric. SENSORS AND ACTUATORS A-PHYSICAL, 339 (113519). [PMID:]
22. Weijuan Zou, Longchen Wang, Junnian Hao, Lixian Jiang, Wenxian Du, Tao Ying, Xiaojun Cai, Haitao Ran, Jianrong Wu, Yuanyi Zheng. (2022) Phase-change cascaded nanomedicine for intensive photothermal-enhanced nanocatalytic therapy via tumor oxidative stress amplification. COMPOSITES PART B-ENGINEERING, 234 (109707). [PMID:]
23. Hongwei Pang, Enyao Zhang, Di Zhang, Xiangxue Wang, Bing Zhao, Lijie Liu, Xiaoying Ma, Gang Song, Shujun Yu. (2022) Precursor impact and mechanism analysis of uranium elimination by biochar supported sulfurized nanoscale zero-valent iron. Journal of Environmental Chemical Engineering, 10 (107288). [PMID:]
24. Xue Liu, Zhenfeng Wu, Chunjing Guo, Huimin Guo, Yanguo Su, Qiang Chen, Changgang Sun, Qingming Liu, Daquan Chen, Hongjie Mu. (2022) Hypoxia responsive nano-drug delivery system based on angelica polysaccharide for liver cancer therapy. DRUG DELIVERY, 29 (1): (138-148). [PMID:34967268]
25. Wei Song, Ji Li, Caixia Fu, Zhuoyue Wang, Zhihong Wang, Qiao Wang, Xiaolei Zhang, Yuxin Zhou, Xing Du. (2022) Low consumption and portable technology for dithionite detection based on potassium ferricyanide differential spectrophotometry method in related advanced oxidation processes. ENVIRONMENTAL RESEARCH, 205 (112430). [PMID:34843722]
26. Yue-Cai Yin,Hui-Lei Yu,Zheng-Jiao Luan,Ren-Jie Li,Peng-Fei Ouyang,Jing Liu,Jian-He Xu. (2014-09-23) Unusually broad substrate profile of self-sufficient cytochrome P450 monooxygenase CYP116B4 from Labrenzia aggregata.. Chembiochem : a European journal of chemical biology, 15 ((16)): (2443-2449). [PMID:25236924]

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Sodium dithionite - 59%, high purity , CAS No.7775-14-6