Basic Description

Synonyms	Disodium hydrosulfite \| SODIUM DITHIONITE [MI] \| sodiumdithionite \| Na2S2O4 \| SODIUM HYDROSULFITE [INCI] \| sodiumhydrosulfite \| MFCD00011640 \| Sodium dithionite (Na2S2O4) \| UN1384 \| JVBXVOWTABLYPX-UHFFFAOYSA-L \| Dithionite de sodium \| SODIUM DITHIONITE [I
Specifications & Purity	technical grade
Grade	technical grade
Product Description	Sodium hydrosulfite (Sodium dithionite, Sodium hypodisulfite, Na 2 S 2 O 4 ) is a white crystalline sodium salt. It decomposes in the presence of atmospheric oxygen to afford sodium hydrogen sulfate. It has been prepared by reducing sodium hydrogen sulfite in sulfurous acid solution with zinc. It is widely used for the decolorization prior to dyeing of cloths in the textile industry. Application Sodium hydrosulfite may be employed as a reducing agent for the reduction of graphite oxide in a study. Sodium hydrosulfite has been used as a fluorescent quenching agent in the encapsulation of polynucleotides via production of asymmetric nanoparticles. It has also be used in the form of buffer for the elution of probe labelled proteins involved in the indentification of cellular targets of covalent kinase inhibitors via mass spectrometry method (MS).

Associated Targets(non-human)

Candida albicans (78123 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

INCHI	InChI=1S/2Na.H2O4S2/c;;1-5(2)6(3)4/h;;(H,1,2)(H,3,4)/q2*+1;/p-2
InChi Key	JVBXVOWTABLYPX-UHFFFAOYSA-L
Canonical SMILES	[O-]S(=O)S(=O)[O-].[Na+].[Na+]
Isomeric SMILES	[O-]S(=O)S(=O)[O-].[Na+].[Na+]
PubChem CID	24489
UN Number	1384
Packing Group	II
Molecular Weight	174.11

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
D2315918	Certificate of Analysis	May 11, 2023	S433998
D2315926	Certificate of Analysis	May 11, 2023	S433998
D2315925	Certificate of Analysis	May 11, 2023	S433998
D2315937	Certificate of Analysis	May 11, 2023	S433998
D2426065	Certificate of Analysis	May 11, 2023	S433998

Chemical and Physical Properties

Solubility	water: soluble(lit.)
Melt Point(°C)	300°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07, GHS02
Signal	Danger
Hazard Statements	H319:Causes serious eye irritation H302:Harmful if swallowed H402:Harmful to aquatic life H251:Self-heating; may catch fire
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P270:Do not eat, drink or smoke when using this product. P337+P313:IF eye irritation persists: Get medical advice/attention. P330:Rinse mouth. P235+P410:Keep cool. Protect from sunlight. P301+P312+P330:IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.
Class	4.2

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Junkai Jiang, Jialiang Xie, Liang Zhou, Wei Han, Jing Ye, Daorun Hu, Weichang Xie, Jianbin Qiu, Runfu Chen, Xiaolei Wang. (2023) Near infrared responsive nitric oxide and carbon monoxide nanoplatform for synergistic photodynamic therapy against periodontitis. CHEMICAL ENGINEERING JOURNAL, (21): (147850). [PMID:26134560] [10.1016/j.cej.2023.147850]
2. Yonghong Fan, Juan Pei, Yinhua Qin, Huifang Du, Xiaohang Qu, Wenya Li, Boyue Huang, Ju Tan, Yong Liu, Gang Li, Ming Ke, Youqian Xu, Chuhong Zhu. (2024) Construction of tissue-engineered vascular grafts with enhanced patency by integrating heparin, cell-adhesive peptide, and carbon monoxide nanogenerators into acellular blood vessels. Bioactive Materials, 34 (221). [PMID:38235307] [10.1016/j.bioactmat.2023.12.015]
3. Xuefang Zhao, Hui Xu, Minzhang Chen, Yong Chen, Xiuqing Kong. (2024) Enhancement of norfloxacin degradation by citrate in S-nZVI@Ps system: Chelation and FeS layer. ENVIRONMENTAL RESEARCH, 245 (117981). [PMID:38142729] [10.1016/j.envres.2023.117981]
4. Chen Zhao, Hongmei Xu, Yating Meng, Yu Wang, Shaomin Shuang, Chuan Dong. (2023) Anthraquinone-based Schiff base fluorescent probe for the sequential sensing of Al3+ and pyrophosphate in a near-perfect aqueous solution and bioimaging. JOURNAL OF MOLECULAR LIQUIDS, 391 (15): (123326). [PMID:15922294] [10.1016/j.molliq.2023.123326]
5. Hailan Wang, Lingna Wang, Enchao Li, Ruobin Dai, Zhiwei Wang. (2023) Efficacies and mechanisms of different cleaning strategies for NF and RO membranes in a full-scale zero liquid discharge system. Journal of Water Process Engineering, 56 (6): (104308). [PMID:22155786] [10.1016/j.jwpe.2023.104308]
6. Peicheng Huang, Weichun Yang, Qingzhu Li, Qi Liao, Mengying Si, Meiqing Shi, Zhihui Yang. (2023) A novel slow-release selenium approach for cadmium reduction and selenium enrichment in rice (Oryza sativa L.). CHEMOSPHERE, 342 (20): (140183). [PMID:37726061] [10.1016/j.chemosphere.2023.140183]
7. Dongdong Wang, Mu Li, Hanning Zhang, Congshu Feng, Lili Wu, Lesan Yan. (2023) A Novel Redox-Sensitive Drug Delivery System Based on Trimethyl-Locked Polycarbonate. BIOMACROMOLECULES, 24 (9): (4303–4315). [PMID:37585690] [10.1021/acs.biomac.3c00702]
8. Xin Jin, Zelin Ou, Guowei Zhang, Rong Shi, Jumin Yang, Wenguang Liu, Gaoxing Luo, Jun Deng, Wei Wang. (2023) A CO-mediated photothermal therapy to kill drug-resistant bacteria and minimize thermal injury for infected diabetic wound healing. Biomaterials Science, [PMID:37531204] [10.1039/D3BM00774J]
9. Ye Ru-Yi, Song Juan, Zhang Zhi-Jun, Yu Hui-Lei. (2023) Prokaryotic expression and characterization of artificial self-sufficient CYP120A monooxygenases. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 107 (18): (5727-5737). [PMID:37477695] [10.1007/s00253-023-12678-y]
10. Jinhai Xie, Shuangyu Tian, Hanning Zhang, Congshu Feng, Yingchao Han, Honglian Dai, Lesan Yan. (2023) A Novel NQO1 Enzyme-Responsive Polyurethane Nanocarrier for Redox-Triggered Intracellular Drug Release. BIOMACROMOLECULES, 24 (5): (2225–2236). [PMID:37040694] [10.1021/acs.biomac.3c00134]
11. Wenfu Ma, Xuhui Liu, Minhui Yang, Qingxiang Hong, Lingjie Meng, Qiuyang Zhang, Jie Chen, Changjiang Pan. (2023) Fabrication of CO-releasing surface to enhance the blood compatibility and endothelialization of TiO2 nanotubes on titanium surface. Biomaterials Advances, 149 (213393). [PMID:36966654] [10.1016/j.bioadv.2023.213393]
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19. Zhuoyue Wang, Wei Song, Ji Li, Xiaolei Zhang, Hongjie Wang. (2022) Optimization and mechanism of Tetrabromobisphenol A removal by dithionite under anaerobic conditions: Response surface methodology and degradation pathway. JOURNAL OF ENVIRONMENTAL MANAGEMENT, 321 (116034). [PMID:36027733] [10.1016/j.jenvman.2022.116034]
20. Kai Sun, Jiaying Yu, Jinzhong Hu, Jian Chen, Jia Song, Zhixin Chen, Zhuoer Cai, Zhuoxuan Lu, Liming Zhang, Zhifei Wang. (2022) Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment. Acta Biomaterialia, 148 (230). [PMID:35724919] [10.1016/j.actbio.2022.06.026]
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24. Hongwei Pang, Enyao Zhang, Di Zhang, Xiangxue Wang, Bing Zhao, Lijie Liu, Xiaoying Ma, Gang Song, Shujun Yu. (2022) Precursor impact and mechanism analysis of uranium elimination by biochar supported sulfurized nanoscale zero-valent iron. Journal of Environmental Chemical Engineering, 10 (107288). [PMID:] [10.1016/j.jece.2022.107288]
25. Xue Liu, Zhenfeng Wu, Chunjing Guo, Huimin Guo, Yanguo Su, Qiang Chen, Changgang Sun, Qingming Liu, Daquan Chen, Hongjie Mu. (2022) Hypoxia responsive nano-drug delivery system based on angelica polysaccharide for liver cancer therapy. DRUG DELIVERY, 29 (1): (138-148). [PMID:34967268] [10.1080/10717544.2021.2021324]
26. Wei Song, Ji Li, Caixia Fu, Zhuoyue Wang, Zhihong Wang, Qiao Wang, Xiaolei Zhang, Yuxin Zhou, Xing Du. (2022) Low consumption and portable technology for dithionite detection based on potassium ferricyanide differential spectrophotometry method in related advanced oxidation processes. ENVIRONMENTAL RESEARCH, 205 (112430). [PMID:34843722] [10.1016/j.envres.2021.112430]
27. Lei Xu, Yuting Wang, Erqun Song, Yang Song. (2021) Nucleophilic and redox properties of polybrominated diphenyl ether derived-quinone/hydroquinone metabolites are responsible for their neurotoxicity. JOURNAL OF HAZARDOUS MATERIALS, 420 (126697). [PMID:34329100] [10.1016/j.jhazmat.2021.126697]
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29. Gebremedhin G. Aregay, Jawad Ali, Ajmal Shahzad, Jerosha Ifthikar, Daniel T. Oyekunle, Zhuqi Chen. (2021) Application of layered double hydroxide enriched with electron rich sulfide moieties (S2O42−) for efficient and selective removal of vanadium (V) from diverse aqueous medium. SCIENCE OF THE TOTAL ENVIRONMENT, 792 (148543). [PMID:34465035] [10.1016/j.scitotenv.2021.148543]
30. Yuhong Lin, Wukun Zhong, Min Wang, Ziyi Chen, Chunhua Lu, Huanghao Yang. (2021) Multifunctional Carbon Monoxide Prodrug-Loaded Nanoplatforms for Effective Photoacoustic Imaging-Guided Photothermal/Gas Synergistic Therapy. ACS Applied Bio Materials, 4 (5): (4557–4564). [PMID:35006792] [10.1021/acsabm.1c00285]
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32. Lianglin Zhang, Shuwei Lin, Yi Li, Baozong Li, Yonggang Yang. (2021) Ala–Ala dipeptides with a semi-perfluoroalkyl chain: chirality driven molecular packing difference and self-assembly driven chiral transfer. NEW JOURNAL OF CHEMISTRY, 45 (6): (3193-3201). [PMID:] [10.1039/D0NJ05676F]
33. Xizi Yu, Lie Xiang, Sheng Yang, Shuanglin Qu, Xianqing Zeng, Yibo Zhou, Ronghua Yang. (2021) A near-infrared fluorogenic probe with fast response for detecting sodium dithionite in living cells. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 245 (118887). [PMID:32927301] [10.1016/j.saa.2020.118887]
34. Dan Li, Zhixiang Zeng, Di Lu, Feng Nie, Lele Wen, Lijing Zhu. (2019) Synthesis and Application of a Conjugated Polydianion-Based Single-Ion Conducting Polymer for High-Performance Solid Lithium-Ion Batteries. ChemElectroChem, 6 (10): (2707-2714). [PMID:] [10.1002/celc.201900553]
35. Zhiyin Xiao, Ran Jiang, Jing Jin, Xiuqin Yang, Binyu Xu, Xiaoming Liu, Yabing He, Yi He. (2019) Diiron(II) pentacarbonyl complexes as CO-releasing molecules: their synthesis, characterization, CO-releasing behaviour and biocompatibility. DALTON TRANSACTIONS, 48 (2): (468-477). [PMID:30488059] [10.1039/C8DT03982H]
36. Yang Lizhe, Gao Jie, Liu Yingying, Zhang Zijun, Zou Motong, Liao Qianjiahua, Shang Jingge. (2018) Removal of Methyl Orange from Water Using Sulfur-Modified nZVI Supported on Biochar Composite. WATER AIR AND SOIL POLLUTION, 229 (11): (1-10). [PMID:] [10.1007/s11270-018-3992-x]
37. Jie Gao, Lizhe Yang, Yingying Liu, Fengli Shao, Qianjiahua Liao, Jingge Shang. (2018) Scavenging of Cr(VI) from aqueous solutions by sulfide-modified nanoscale zero-valent iron supported by biochar. Journal of the Taiwan Institute of Chemical Engineers, 91 (449). [PMID:] [10.1016/j.jtice.2018.06.033]
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Sodium hydrosulfite - technical grade, high purity , CAS No.7775-14-6