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Sodium Palmitate - >97.0%(GC)(T), high purity , CAS No.408-35-5

9 Citations

≥97%(GC)(T)

CAS#: 408-35-5
Formula: C₁₆H₃₁NaO₂
Molecular Weight: 278.41
Beilstein Registry Number: 3575880
MDL number: MFCD00002749
PubChem CID: 2735111
PubChem SID: 488192703

Item Number

S161420

Grouped product items
SKU	Size	Availability	Price
S161420-1g	1g	In stock	$14.90
S161420-5g	5g	In stock	$58.90
S161420-25g	25g	In stock	$265.90
S161420-100g	100g	In stock	$955.90
S161420-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$4,301.90

View related series

carboxylic acid Polymer / polymer reagent

Basic Description

Synonyms	SODIUM PALMITATE \| 408-35-5 \| Palmitic acid sodium salt \| Hexadecanoic acid, sodium salt \| Sodium hexadecanoate \| sodium;hexadecanoate \| Palmitic acid, sodium salt \| Palmitic acid (sodium) \| JQ43KP6296 \| Hexadecanoic acid, sodium salt (1:1) \| SODIUM HEXADECANOATE-D31 \| Sodium
Specifications & Purity	≥97%(GC)(T)
Biochemical and Physiological Mechanisms	Sodium palmitate is the sodium salt of palmitic acid, which is a component of hard soap. Palmitic acid is a common fatty acid produced during Fatty acid synthesis. Sodium palmitate can enhance lipogenesis and cellular steatosis in various cells. Palmitic
Shipped In	Normal

Associated Targets(Human)

FFAR3 Tchem Free fatty acid receptor 3 (304 Activities)

Discover Target: FFAR3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488192703
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488192703
IUPAC Name	sodium;hexadecanoate
INCHI	InChI=1S/C16H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18;/h2-15H2,1H3,(H,17,18);/q;+1/p-1
InChi Key	GGXKEBACDBNFAF-UHFFFAOYSA-M
Canonical SMILES	CCCCCCCCCCCCCCCC(=O)[O-].[Na+]
Isomeric SMILES	CCCCCCCCCCCCCCCC(=O)[O-].[Na+]
WGK Germany	1
RTECS	RT4945000
PubChem CID	2735111
Molecular Weight	278.41
Beilstein	3575880
Reaxy-Rn	3575882

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

14 results found

Lot Number	Certificate Type	Date	Item
L1803070	Certificate of Analysis	Jan 22, 2024	S161420
E2304405	Certificate of Analysis	May 16, 2023	S161420
A2411020	Certificate of Analysis	Feb 16, 2023	S161420
A2429408	Certificate of Analysis	Feb 16, 2023	S161420
C2313040	Certificate of Analysis	Feb 16, 2023	S161420
C2313245	Certificate of Analysis	Feb 16, 2023	S161420
C2313246	Certificate of Analysis	Feb 16, 2023	S161420
C2313266	Certificate of Analysis	Feb 16, 2023	S161420
C2313267	Certificate of Analysis	Feb 16, 2023	S161420
C2313298	Certificate of Analysis	Feb 16, 2023	S161420
C2313244	Certificate of Analysis	Dec 12, 2022	S161420
C2313262	Certificate of Analysis	Dec 12, 2022	S161420
C2313264	Certificate of Analysis	Dec 12, 2022	S161420
C2313265	Certificate of Analysis	Dec 12, 2022	S161420

Chemical and Physical Properties

Solubility	Solubility in hot EtOH(50vol%) very faint turbidity
Melt Point(°C)	283-290 °C (lit.)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help.
WGK Germany	1
RTECS	RT4945000
Reaxy-Rn	3575882

Citations of This Product

1. Han Wenrun, Zhang Dandan, Zhang Peng, Tao Qianqian, Du Xiaoli, Yu Chunquan, Dong Pengzhi, Zhu Yan. (2023) Danlou Recipe promotes cholesterol efflux in macrophages RAW264.7 and reverses cholesterol transport in mice with hyperlipidemia induced by P407. BMC Complementary Medicine and Therapies, 23 (1): (1-14). [PMID:38066464]
2. Tian Xiaorong, Wang Yuxin, Yuan Mengshu, Zheng Weiping, Zuo Huaiwen, Zhang Xinru, Song Hongli. (2023) Heme Oxygenase-1-Modified BMMSCs Activate AMPK–Nrf2–FTH1 to Reduce Severe Steatotic Liver Ischemia–Reperfusion Injury. DIGESTIVE DISEASES AND SCIENCES, (5): (1-16). [PMID:37707747]
3. Yanzhuo Yang, Qingting Yu, Bin Li, Zuisu Yang, Shuai Zhang, Falei Yuan. (2023) Palmitate lipotoxicity is closely associated with the fatty acid-albumin complexes in BV-2 microglia. PLoS One, 18 (4): (e0281189). [PMID:37079515]
4. Xuebin Gao, Xiaozhuan Lin, Yan Xin, Xuan Zhu, Xiang Li, Ming Chen, Zhigang Huang, Honghui Guo. (2023) Dietary cholesterol drives the development of nonalcoholic steatohepatitis by altering gut microbiota mediated bile acid metabolism in high-fat diet fed mice. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 117 (109347). [PMID:37031879]
5. Jiang Hui, Mao Tangyou, Sun Zhongmei, Shi Lei, Han Xiao, Zhang Yang, Zhang Xiaosi, Wang Jiali, Hu Juncong, Zhang Liming, Li Junxiang, Han Haixiao. (2022) Yinchen Linggui Zhugan decoction ameliorates high fat diet-induced nonalcoholic fatty liver disease by modulation of SIRT1/Nrf2 signaling pathway and gut microbiota. Frontiers in Microbiology, 13 [PMID:36578580]
6. Huanhuan Ma, Yunxia Ma, Zeren Dawa, Yufeng Yao, Meiqi Wang, Kaihui Zhang, Chenchen Zhu, Fangle Liu, Chaozhan Lin. (2022) Diterpenoid Alkaloids Isolated from Delphinium brunonianum and Their Inhibitory Effects on Hepatocytes Lipid Accumulation. MOLECULES, 27 (7): (2257). [PMID:35408656]
7. Han Jia, Shaoyan Wang, Zhe Wang, Qiang Wang, Haidong Jia, Lin Song, Xuwen Qin, Fangning Fan, Zhe Li, Pan Huang. (2022) Investigation of anionic group effects on the shale inhibition performance of fatty acid-based ionic liquids and their inhibition mechanism. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 636 (128135). [PMID:]
8. Han Jia, Shaoyan Wang, Yingbiao Xu, Tingyi Wang, Lingyu Zhang, Jinyong Song, Xuehao Zhang, Lin Song, Haidong Jia, Hui Yan. (2022) Systematic investigation on the abnormal surface and interfacial activity of fatty acid ionic liquids. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 634 (127902). [PMID:]
9. Baogui Wang,Jing Fu,Lumin Li,Deming Gong,Xuefang Wen,Ping Yu,Zheling Zeng. (2016-03-05) Medium-chain fatty acid reduces lipid accumulation by regulating expression of lipid-sensing genes in human liver cells with steatosis.. International journal of food sciences and nutrition, 67 ((3)): (288-297). [PMID:26932533]

References

1. Zhang J et al.. (2020) N1-Methylnicotinamide Improves Hepatic Insulin Sensitivity via Activation of SIRT1 and Inhibition of FOXO1 Acetylation.. J Diabetes Res, 2020 (1080152). [PMID:32280711]
2. Daniela Lamers,Raphaela Schlich,Sabrina Greulich,Shlomo Sasson,Henrike Sell,Jürgen Eckel. (2010-06-04) Oleic acid and adipokines synergize in inducing proliferation and inflammatory signalling in human vascular smooth muscle cells.. Journal of cellular and molecular medicine, 15 ((5)): (1177-1188). [PMID:20518853]
3. Jin Zhang,Esther Nuebel,Dona R R Wisidagama,Kiyoko Setoguchi,Jason S Hong,Christine M Van Horn,Sarah S Imam,Laurent Vergnes,Cindy S Malone,Carla M Koehler,Michael A Teitell. (2012-05-12) Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells.. Nature protocols, 7 ((6)): (1068-1085). [PMID:22576106]
4. Chenjing Yang,Cho Cho Aye,Xiaoxin Li,Angels Diaz Ramos,Antonio Zorzano,Silvia Mora. (2012-06-30) Mitochondrial dysfunction in insulin resistance: differential contributions of chronic insulin and saturated fatty acid exposure in muscle cells.. Bioscience reports, 32 ((5)): (465-478). [PMID:22742515]
5. Ion Anghel,Alina Maria Holban,Alexandru Mihai Grumezescu,Ecaterina Andronescu,Anton Ficai,Alina Georgiana Anghel,Maria Maganu,Veronica Laz R,Mariana Carmen Chifiriuc. (2013-01-01) Modified wound dressing with phyto-nanostructured coating to prevent staphylococcal and pseudomonal biofilm development.. Nanoscale research letters, 7 ((1)): (690-690). [PMID:23272823]
6. Sabeera Bonala,Craig McFarlane,Jackie Ang,Radiance Lim,Marcus Lee,Hillary Chua,Sudarsanareddy Lokireddy,Patnam Sreekanth,Melvin Khee Shing Leow,Khoo Chin Meng,Tai E Shyong,Yung Seng Lee,Peter D Gluckman,Mridula Sharma,Ravi Kambadur. (2013-08-10) Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity.. Molecular endocrinology (Baltimore, Md.), 27 ((9)): (1518-1535). [PMID:23927930]
7. Ryan G Snodgrass,Shurong Huang,Il-Whan Choi,John C Rutledge,Daniel H Hwang. (2013-09-18) Inflammasome-mediated secretion of IL-1β in human monocytes through TLR2 activation; modulation by dietary fatty acids.. Journal of immunology (Baltimore, Md. : 1950), 191 ((8)): (4337-4347). [PMID:24043885]
8. Nina Dinjaski,Mar Fernández-Gutiérrez,Shivaram Selvam,Francisco J Parra-Ruiz,Susan M Lehman,Julio San Román,Ernesto García,José L García,Andrés J García,María Auxiliadora Prieto. (2013-10-08) PHACOS, a functionalized bacterial polyester with bactericidal activity against methicillin-resistant Staphylococcus aureus.. Biomaterials, 35 ((1)): (14-24). [PMID:24094939]
9. Belén Picatoste,Elisa Ramírez,Alicia Caro-Vadillo,Cristian Iborra,Sara Ares-Carrasco,Jesús Egido,José Tuñón,Oscar Lorenzo. (2013-12-05) Sitagliptin reduces cardiac apoptosis, hypertrophy and fibrosis primarily by insulin-dependent mechanisms in experimental type-II diabetes. Potential roles of GLP-1 isoforms.. PloS one, 8 ((10)): (e78330-e78330). [PMID:24302978]
10. Xiuqing Wei,Bilun Ke,Zhiyun Zhao,Xin Ye,Zhanguo Gao,Jianping Ye. (2014-04-18) Regulation of insulin degrading enzyme activity by obesity-associated factors and pioglitazone in liver of diet-induced obese mice.. PloS one, 9 ((4)): (e95399-e95399). [PMID:24740421]
11. Jovan Kuzmicic,Valentina Parra,Hugo E Verdejo,Camila López-Crisosto,Mario Chiong,Lorena García,Michael D Jensen,David A Bernlohr,Pablo F Castro,Sergio Lavandero. (2014-08-06) Trimetazidine prevents palmitate-induced mitochondrial fission and dysfunction in cultured cardiomyocytes.. Biochemical pharmacology, 91 ((3)): (323-336). [PMID:25091560]
12. Lisa S Pike Winer,Min Wu. (2014-11-02) Rapid analysis of glycolytic and oxidative substrate flux of cancer cells in a microplate.. PloS one, 9 ((10)): (e109916-e109916). [PMID:25360519]
13. Dongmei Shi,Xi Zhan,Xiaofeng Yu,Minglei Jia,Ying Zhang,Jianfeng Yao,Xiaona Hu,Zhijun Bao. (2014-11-20) Inhibiting CB1 receptors improves lipogenesis in an in vitro non-alcoholic fatty liver disease model.. Lipids in health and disease, 13 (173-173). [PMID:25406988]
14. Ramasri Sathanoori,Karl Swärd,Björn Olde,David Erlinge. (2015-05-06) The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells.. PloS one, 10 ((5)): (e0125111-e0125111). [PMID:25938443]
15. . () Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promote monocyte adhesion and impair insulin transcytosis.. American journal of ph, [PMID:25944880]
16. Maria-Christina Scherzberg,Andreas Kiehl,Aleksandra Zivkovic,Holger Stark,Jürgen Stein,Robert Fürst,Dieter Steinhilber,Sandra Ulrich-Rückert. (2015-06-06) Structural modification of resveratrol leads to increased anti-tumor activity, but causes profound changes in the mode of action.. Toxicology and applied pharmacology, 287 ((1)): (67-76). [PMID:26044878]
17. Hayden Weng Siong Tan,Arthur Yi Loong Sim,Su Ling Huang,Ying Leng,Yun Chau Long. (2015-09-17) HC toxin (a HDAC inhibitor) enhances IRS1-Akt signalling and metabolism in mouse myotubes.. Journal of molecular endocrinology, 55 ((3)): (197-207). [PMID:26373795]
18. Aritro Nath,Irene Li,Lewis R Roberts,Christina Chan. (2015-10-02) Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma.. Scientific reports, 5 (14752-14752). [PMID:26424075]
19. Michaela Schäfer,Christian U Oeing,Maria Rohm,Ezgi Baysal-Temel,Lorenz H Lehmann,Ralf Bauer,H Christian Volz,Michael Boutros,Daniela Sohn,Carsten Sticht,Norbert Gretz,Katrin Eichelbaum,Tessa Werner,Marc N Hirt,Thomas Eschenhagen,Karin Müller-Decker,Oliver Strobel,Thilo Hackert,Jeroen Krijgsveld,Hugo A Katus,Mauricio Berriel Diaz,Johannes Backs,Stephan Herzig. (2016-02-26) Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia.. Molecular metabolism, 5 ((2)): (67-78). [PMID:26909315]
20. Yong Zhang,Zhiyun Zhao,Bilun Ke,Lin Wan,Hui Wang,Jianping Ye. (2016-03-02) Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function.. PloS one, 11 ((3)): (e0150454-e0150454). [PMID:26930489]
21. P S Dalvi,J A Chalmers,V Luo,D-Yd Han,L Wellhauser,Y Liu,D Q Tran,J Castel,S Luquet,M B Wheeler,D D Belsham. (2016-10-25) High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons.. International journal of obesity (2005), 41 ((1)): (149-158). [PMID:27773938]
22. William T Hay,Jeffrey A Byars,George F Fanta,Gordon W Selling. (2017-02-13) Rheological characterization of solutions and thin films made from amylose-hexadecylammonium chloride inclusion complexes and polyvinyl alcohol.. Carbohydrate polymers, 161 (140-148). [PMID:28189221]
23. Tae Woo Jung,Hyoung-Chun Kim,A M Abd El-Aty,Ji Hoon Jeong. (2017-05-05) Protectin DX ameliorates palmitate- or high-fat diet-induced insulin resistance and inflammation through an AMPK-PPARα-dependent pathway in mice.. Scientific reports, 7 ((1)): (1397-1397). [PMID:28469249]
24. Jun-Su Lee,Sijeong Bae,Hye-Suk Kang,Seung-Soon Im,Young-Ah Moon. (2017-05-30) Liver receptor homolog-1 regulates mouse superoxide dismutase 2.. Biochemical and biophysical research communications, 489 ((3)): (299-304). [PMID:28552526]
25. Marta Riera-Borrull,Víctor D Cuevas,Bárbara Alonso,Miguel A Vega,Jorge Joven,Elena Izquierdo,Ángel L Corbí. (2017-10-25) Palmitate Conditions Macrophages for Enhanced Responses toward Inflammatory Stimuli via JNK Activation.. Journal of immunology (Baltimore, Md. : 1950), 199 ((11)): (3858-3869). [PMID:29061766]
26. Tae Woo Jung,Yoon Hee Chung,Hyoung-Chun Kim,A M Abd El-Aty,Ji Hoon Jeong. (2017-11-08) Hyperlipidemia-induced hepassocin in the liver contributes to insulin resistance in skeletal muscle.. Molecular and cellular endocrinology, 470 (26-33). [PMID:29111387]
27. Tae Woo Jung,Sun-Young Kim,Da-Som Kim,Eui-Cheol Shin,Yong Bae Park,Kyoung-Tae Lee. (2018-03-30) Euodia daniellii Hemsl. (Bee-Bee Tree) Oil Attenuates Palmitate-Induced Lipid Accumulation and Apoptosis in Hepatocytes.. Pharmacology, 101 ((5-6)): (298-308). [PMID:29597210]
28. Eleonora Cremonini,Patricia I Oteiza. (2018-04-03) (-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells.. Archives of biochemistry and biophysics, 646 (55-63). [PMID:29608879]
29. Soyeon Park,Ji-Hwan Park,Hee-Jung Jung,Jin-Hyeok Jang,Sanghyun Ahn,Younah Kim,Pann-Ghill Suh,Sehyun Chae,Jong Hyuk Yoon,Sung Ho Ryu,Daehee Hwang. (2018-08-05) A secretome profile indicative of oleate-induced proliferation of HepG2 hepatocellular carcinoma cells.. Experimental & molecular medicine, 50 ((8)): (1-14). [PMID:30076294]
30. Dongdong Jiang,Fang Wan. (2018-08-17) Exendin-4 protects INS-1 cells against palmitate-induced apoptosis through the IRE1α-Xbp1 signaling pathway.. Experimental and therapeutic medicine, 16 ((2)): (1029-1035). [PMID:30112049]
31. Love Sharma,Nazir A Lone,Rachel M Knott,Adil Hassan,Tasduq Abdullah. (2018-09-13) Trigonelline prevents high cholesterol and high fat diet induced hepatic lipid accumulation and lipo-toxicity in C57BL/6J mice, via restoration of hepatic autophagy.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 121 (283-296). [PMID:30208301]
32. Clay O Lacefield,Eftychios A Pnevmatikakis,Liam Paninski,Randy M Bruno. (2019-02-21) Reinforcement Learning Recruits Somata and Apical Dendrites across Layers of Primary Sensory Cortex.. Cell reports, 26 ((8)): (2000-2008). [PMID:30784583]
33. Chulhun Park,Nileshkumar Meghani,Hardik Amin,Phuong H-L Tran,Thao T-D Tran,Van H Nguyen,Beom-Jin Lee. (2019-04-17) The roles of short and long chain fatty acids on physicochemical properties and improved cancer targeting of albumin-based fattigation-platform nanoparticles containing doxorubicin.. International journal of pharmaceutics, 564 (124-135). [PMID:30991133]
34. José M S Fernández-Calleja,Lianne M S Bouwman,Hans J M Swarts,Annemarie Oosting,Jaap Keijer,Evert M van Schothorst. (2019-08-10) Extended indirect calorimetry with isotopic CO2 sensors for prolonged and continuous quantification of exogenous vs. total substrate oxidation in mice.. Scientific reports, 9 ((1)): (11507-11507). [PMID:31395916]
35. Kuang-Tzu Huang,Kuang-Den Chen,Li-Wen Hsu,Chao-Pin Kung,Shu-Rong Li,Chien-Chih Chen,King-Wah Chiu,Shigeru Goto,Chao-Long Chen. (2020-01-24) Decreased PEDF Promotes Hepatic Fatty Acid Uptake and Lipid Droplet Formation in the Pathogenesis of NAFLD.. Nutrients, 12 ((1)): [PMID:31968655]
36. Jennifer Vogel,Jianning Yin,Liansheng Su,Sharon X Wang,Richard Zessis,Sena Fowler,Chun-Hao Chiu,Aaron C Wilson,Amy Chen,Frederic Zecri,Gordon Turner,Thomas M Smith,Brian DeChristopher,Heming Xing,Deborah M Rothman,Xinming Cai,Alina Berdichevsky. (2020-02-23) A Phenotypic Screen Identifies Calcium Overload as a Key Mechanism of β-Cell Glucolipotoxicity.. Diabetes, 69 ((5)): (1032-1041). [PMID:32079579]
37. ChangHyuk Kwon,Jaw Long Sun,Ji Hoon Jeong,Tae Woo Jung. (2020-04-05) Humanin attenuates palmitate-induced hepatic lipid accumulation and insulin resistance via AMPK-mediated suppression of the mTOR pathway.. Biochemical and biophysical research communications, 526 ((2)): (539-545). [PMID:32245619]
38. Nilakshi Kulathunga,Susumu Kohno,Paing Linn,Yuuki Nishimoto,Shin-Ichi Horike,Mikhail I Zaraiskii,Sharad Kumar,Hayato Muranaka,Chiaki Takahashi. (2020-05-22) Peripubertal high-fat diet promotes c-Myc stabilization in mammary gland epithelium.. Cancer science, 111 ((7)): (2336-2348). [PMID:32437590]
39. Jhih-Wei Hsu,Chung-Yi Nien,Szu-Ching Yeh,Feng-Yuan Tsai,Hsin-Wei Chen,Tzong-Shyuan Lee,Shen-Liang Chen,Yung-Hsi Kao,Tsui-Chun Tsou. (2020-06-12) Phthalate exposure causes browning-like effects on adipocytes in vitro and in vivo.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 142 (111487-111487). [PMID:32522588]
40. Jiani Wang,Christina Ortiz,Lindsey Fontenot,Riya Mukhopadhyay,Ying Xie,Ivy Ka Man Law,David Q Shih,S Anjani Mattai,Zhaoping Li,Hon Wai Koon. (2020-08-01) Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice.. Scientific reports, 10 ((1)): (12785-12785). [PMID:32733043]
41. Vanja Panic,Stephanie Pearson,James Banks,Trevor S Tippetts,Jesse N Velasco-Silva,Sanghoon Lee,Judith Simcox,Gisela Geoghegan,Claire L Bensard,Tyler van Ry,Will L Holland,Scott A Summers,James Cox,Gregory S Ducker,Jared Rutter,Claudio J Villanueva. (2020-08-17) Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis.. eLife, 9 [PMID:32795388]
42. Wen-Chih Lee,Xing Ji,Itzhak Nissim,Fanxin Long. (2020-09-10) Malic Enzyme Couples Mitochondria with Aerobic Glycolysis in Osteoblasts.. Cell reports, 32 ((10)): (108108-108108). [PMID:32905773]
43. Qiyi Zhao,Jiayu Liu,Hong Deng,Ruiying Ma,Jian-You Liao,Huixin Liang,Jingxiong Hu,Jiaqian Li,Zhiyong Guo,Junchao Cai,Xiaoding Xu,Zhiliang Gao,Shicheng Su. (2020-09-16) Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.. Cell, 183 ((1)): (76-93). [PMID:32931733]
44. Seung-Min Lee,Seol Hee Lee,Youngae Jung,Younglang Lee,Jong Hyun Yoon,Jeong Yi Choi,Chae Young Hwang,Young Hoon Son,Sung Sup Park,Geum-Sook Hwang,Kwang-Pyo Lee,Ki-Sun Kwon. (2020-11-11) FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging.. Nature communications, 11 ((1)): (5661-5661). [PMID:33168829]
45. S N Patel,M Ishahak,D Chaimov,A Velraj,D LaShoto,D W Hagan,P Buchwald,E A Phelps,A Agarwal,C L Stabler. (2021-02-14) Organoid microphysiological system preserves pancreatic islet function within 3D matrix.. Science advances, 7 ((7)): [PMID:33579705]
46. Sarah Krantz,Young-Mee Kim,Shubhi Srivastava,Joseph W Leasure,Peter T Toth,Glenn Marsboom,Jalees Rehman. (2021-11-18) Mitophagy mediates metabolic reprogramming of induced pluripotent stem cells undergoing endothelial differentiation.. The Journal of biological chemistry, 297 ((6)): (101410-101410). [PMID:34785214]
47. Sabeera Bonala,Sudarsanareddy Lokireddy,Craig McFarlane,Sreekanth Patnam,Mridula Sharma,Ravi Kambadur. (2014-01-24) Myostatin induces insulin resistance via Casitas B-lineage lymphoma b (Cblb)-mediated degradation of insulin receptor substrate 1 (IRS1) protein in response to high calorie diet intake.. The Journal of biological chemistry, 289 ((11)): (7654-7670). [PMID:24451368]
48. Matthew D Greseth,Paula Traktman. (2014-03-22) De novo fatty acid biosynthesis contributes significantly to establishment of a bioenergetically favorable environment for vaccinia virus infection.. PLoS pathogens, 10 ((3)): (e1004021-e1004021). [PMID:24651651]
49. Timothy J Sargeant,Bethan Lloyd-Lewis,Henrike K Resemann,Antonio Ramos-Montoya,Jeremy Skepper,Christine J Watson. (2014-10-07) Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization.. Nature cell biology, 16 ((11)): (1057-1068). [PMID:25283994]
50. Sanda Win,Tin Aung Than,Bao Han Allison Le,Carmen García-Ruiz,Jose C Fernandez-Checa,Neil Kaplowitz. (2015-02-11) Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.. Journal of hepatology, 62 ((6)): (1367-1374). [PMID:25666017]
51. Xue-qun Zhang,Yue Pan,Chao-hui Yu,Cheng-fu Xu,Lei Xu,You-ming Li,Wei-xing Chen. (2015-07-28) PDIA3 Knockdown Exacerbates Free Fatty Acid-Induced Hepatocyte Steatosis and Apoptosis.. PloS one, 10 ((7)): (e0133882-e0133882). [PMID:26214517]
52. Dimitra K Georgiou,Adan Dagnino-Acosta,Chang Seok Lee,Deric M Griffin,Hui Wang,William R Lagor,Robia G Pautler,Robert T Dirksen,Susan L Hamilton. (2015-08-08) Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism.. The Journal of biological chemistry, 290 ((39)): (23751-23765). [PMID:26245899]
53. Tatsuya Tominaga,Rajesh K Dutta,Darukeshwara Joladarashi,Toshio Doi,Janardan K Reddy,Yashpal S Kanwar. (2015-11-19) Transcriptional and Translational Modulation of myo-Inositol Oxygenase (Miox) by Fatty Acids: IMPLICATIONS IN RENAL TUBULAR INJURY INDUCED IN OBESITY AND DIABETES.. The Journal of biological chemistry, 291 ((3)): (1348-1367). [PMID:26578517]
54. Gerard Aragonès,Manuel Suárez,Andrea Ardid-Ruiz,Maria Vinaixa,Miguel A Rodríguez,Xavier Correig,Lluís Arola,Cinta Bladé. (2016-04-23) Dietary proanthocyanidins boost hepatic NAD(+) metabolism and SIRT1 expression and activity in a dose-dependent manner in healthy rats.. Scientific reports, 6 (24977-24977). [PMID:27102823]
55. Shaojie Wang,Xiaojie Li,Hongli Guo,Zihang Yuan,Tao Wang,Luyong Zhang,Zhenzhou Jiang. (2016-08-06) Emodin alleviates hepatic steatosis by inhibiting sterol regulatory element binding protein 1 activity by way of the calcium/calmodulin-dependent kinase kinase-AMP-activated protein kinase-mechanistic target of rapamycin-p70 ribosomal S6 kinase signaling pathway.. Hepatology research : the official journal of the Japan Society of Hepatology, 47 ((7)): (683-701). [PMID:27492505]
56. Ketan Thombare,Stelia Ntika,Xuan Wang,Camilla Krizhanovskii. (2017-05-19) Long chain saturated and unsaturated fatty acids exert opposing effects on viability and function of GLP-1-producing cells: Mechanisms of lipotoxicity.. PloS one, 12 ((5)): (e0177605-e0177605). [PMID:28520810]
57. Marcela Parra-Vargas,Ana Sandoval-Rodriguez,Roberto Rodriguez-Echevarria,Jose Alfredo Dominguez-Rosales,Arturo Santos-Garcia,Juan Armendariz-Borunda. (2018-08-15) Delphinidin Ameliorates Hepatic Triglyceride Accumulation in Human HepG2 Cells, but Not in Diet-Induced Obese Mice.. Nutrients, 10 ((8)): [PMID:30103390]
58. Themis Thoudam,Chae-Myeong Ha,Jaechan Leem,Dipanjan Chanda,Jong-Seok Park,Hyo-Jeong Kim,Jae-Han Jeon,Yeon-Kyung Choi,Suthat Liangpunsakul,Yang Hoon Huh,Tae-Hwan Kwon,Keun-Gyu Park,Robert A Harris,Kyu-Sang Park,Hyun-Woo Rhee,In-Kyu Lee. (2018-12-14) PDK4 Augments ER-Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity.. Diabetes, 68 ((3)): (571-586). [PMID:30523025]
59. Li Lin,Jamie Burke,Sahana Venkatesh,Prabodh Sadana. (2019-07-06) AMPK-SIRT1-independent inhibition of ANGPTL3 gene expression is a potential lipid-lowering mechanism of metformin.. The Journal of pharmacy and pharmacology, 71 ((9)): (1421-1428). [PMID:31273790]
60. Yibao Ma,Wei Wang,Teja Devarakonda,Huiping Zhou,Xiang-Yang Wang,Fadi N Salloum,Sarah Spiegel,Xianjun Fang. (2020-01-31) Functional analysis of molecular and pharmacological modulators of mitochondrial fatty acid oxidation.. Scientific reports, 10 ((1)): (1450-1450). [PMID:31996743]
61. Florian J Weisel,Steven J Mullett,Rebecca A Elsner,Ashley V Menk,Nikita Trivedi,Wei Luo,Daniel Wikenheiser,William F Hawse,Maria Chikina,Shuchi Smita,Laura J Conter,Stephen M Joachim,Stacy G Wendell,Michael J Jurczak,Thomas H Winkler,Greg M Delgoffe,Mark J Shlomchik. (2020-02-19) Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis.. Nature immunology, 21 ((3)): (331-342). [PMID:32066950]
62. Su, et al.. (2021) Vitamin K2 Alleviates Insulin Resistance in Skeletal Muscle by Improving Mitochondrial Function Via SIRT1 Signaling.. Antioxidants & Redox Signaling, 34 (99-117). [PMID:32253917]
63. Ji Hye Yang,Nam Hee Kim,Jun Seop Yun,Eunae Sandra Cho,Yong Hoon Cha,Sue Bean Cho,Seon-Hyeong Lee,So Young Cha,Soo-Youl Kim,Jiwon Choi,Tin-Tin Manh Nguyen,Sunghyouk Park,Hyun Sil Kim,Jong In Yook. (2020-06-04) Snail augments fatty acid oxidation by suppression of mitochondrial ACC2 during cancer progression.. Life science alliance, 3 ((7)): [PMID:32487689]
64. Eugenio Cersosimo,Xiaojing Xu,Tomoko Terasawa,Lily Q Dong. (2020-08-14) Anti-inflammatory and anti-proliferative action of adiponectin mediated by insulin signaling cascade in human vascular smooth muscle cells.. Molecular biology reports, 47 ((9)): (6561-6572). [PMID:32789574]
65. Yen-Hsiang Chang,Hung-Yu Lin,Feng-Chih Shen,Yu-Jih Su,Jiin-Haur Chuang,Tsu-Kung Lin,Chia-Wei Liou,Ching-Yi Lin,Shao-Wen Weng,Pei-Wen Wang. (2020-08-28) The Causal Role of Mitochondrial Dynamics in Regulating Innate Immunity in Diabetes.. Frontiers in endocrinology, 11 (445-445). [PMID:32849261]
66. Hyunjung Lee,Young In Kim,Farida S Nirmala,Ji-Sun Kim,Hyo-Deok Seo,Tae Youl Ha,Young-Jin Jang,Chang Hwa Jung,Jiyun Ahn. (2021-02-04) MiR-141-3p promotes mitochondrial dysfunction in ovariectomy-induced sarcopenia via targeting Fkbp5 and Fibin.. Aging, 13 ((4)): (4881-4894). [PMID:33534778]
67. Youxi Yu,Xiaoju Shi,Qianqian Zheng,Xingtong Wang,Xingkai Liu,Min Tan,Guoyue Lv,Ping Zhang,Robert C Martin,Yan Li. (2021-07-31) Aberrant FGFR4 signaling worsens nonalcoholic steatohepatitis in FGF21KO mice.. International journal of biological sciences, 17 ((10)): (2576-2589). [PMID:34326695]
68. Han Wenrun, Zhang Dandan, Zhang Peng, Tao Qianqian, Du Xiaoli, Yu Chunquan, Dong Pengzhi, Zhu Yan. (2023) Danlou Recipe promotes cholesterol efflux in macrophages RAW264.7 and reverses cholesterol transport in mice with hyperlipidemia induced by P407. BMC Complementary Medicine and Therapies, 23 (1): (1-14). [PMID:38066464]
69. Tian Xiaorong, Wang Yuxin, Yuan Mengshu, Zheng Weiping, Zuo Huaiwen, Zhang Xinru, Song Hongli. (2023) Heme Oxygenase-1-Modified BMMSCs Activate AMPK–Nrf2–FTH1 to Reduce Severe Steatotic Liver Ischemia–Reperfusion Injury. DIGESTIVE DISEASES AND SCIENCES, (5): (1-16). [PMID:37707747]
70. Yanzhuo Yang, Qingting Yu, Bin Li, Zuisu Yang, Shuai Zhang, Falei Yuan. (2023) Palmitate lipotoxicity is closely associated with the fatty acid-albumin complexes in BV-2 microglia. PLoS One, 18 (4): (e0281189). [PMID:37079515]
71. Xuebin Gao, Xiaozhuan Lin, Yan Xin, Xuan Zhu, Xiang Li, Ming Chen, Zhigang Huang, Honghui Guo. (2023) Dietary cholesterol drives the development of nonalcoholic steatohepatitis by altering gut microbiota mediated bile acid metabolism in high-fat diet fed mice. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 117 (109347). [PMID:37031879]
72. Jiang Hui, Mao Tangyou, Sun Zhongmei, Shi Lei, Han Xiao, Zhang Yang, Zhang Xiaosi, Wang Jiali, Hu Juncong, Zhang Liming, Li Junxiang, Han Haixiao. (2022) Yinchen Linggui Zhugan decoction ameliorates high fat diet-induced nonalcoholic fatty liver disease by modulation of SIRT1/Nrf2 signaling pathway and gut microbiota. Frontiers in Microbiology, 13 [PMID:36578580]
73. Huanhuan Ma, Yunxia Ma, Zeren Dawa, Yufeng Yao, Meiqi Wang, Kaihui Zhang, Chenchen Zhu, Fangle Liu, Chaozhan Lin. (2022) Diterpenoid Alkaloids Isolated from Delphinium brunonianum and Their Inhibitory Effects on Hepatocytes Lipid Accumulation. MOLECULES, 27 (7): (2257). [PMID:35408656]
74. Han Jia, Shaoyan Wang, Zhe Wang, Qiang Wang, Haidong Jia, Lin Song, Xuwen Qin, Fangning Fan, Zhe Li, Pan Huang. (2022) Investigation of anionic group effects on the shale inhibition performance of fatty acid-based ionic liquids and their inhibition mechanism. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 636 (128135). [PMID:]
75. Han Jia, Shaoyan Wang, Yingbiao Xu, Tingyi Wang, Lingyu Zhang, Jinyong Song, Xuehao Zhang, Lin Song, Haidong Jia, Hui Yan. (2022) Systematic investigation on the abnormal surface and interfacial activity of fatty acid ionic liquids. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 634 (127902). [PMID:]
76. Baogui Wang,Jing Fu,Lumin Li,Deming Gong,Xuefang Wen,Ping Yu,Zheling Zeng. (2016-03-05) Medium-chain fatty acid reduces lipid accumulation by regulating expression of lipid-sensing genes in human liver cells with steatosis.. International journal of food sciences and nutrition, 67 ((3)): (288-297). [PMID:26932533]

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