Somatostatin 1-28 TFA, CAS No.74315-46-1(free), Agonist of MRGPRX2;Agonist of SST 1 receptor;Agonist of SST 2 receptor;Agonist of SST 3 receptor;Agonist of SST 4 receptor;Agonist of SST 5 receptor

Features and benefits
    Item Number
    S287982
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    S287982-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $800.90
    S287982-2mg
    2mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,200.90
    S287982-5mg
    5mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,820.90

    sst agonist

    Basic Description

    Product NameSomatostatin 1-28 TFA, CAS No.74315-46-1(free)
    GradeMoligand™
    Product Description

    Somatostatin 1-28 TFA circulates in human plasma. Approximately 46% of the total somatostatin-like immunoreactivity in plasma is due to Somatostatin 1-28 TFA.

    Specifications & PurityMoligand™, ≥98%
    Biochemical and Physiological MechanismsSomatostatin receptor agonist, derived from the post-translational cleavage of prosomatostatin.
    SequenceSANSNPAMAPRERKAGCKNFFWKTFTSC(Modifications: Disulfide bridge between 17 - 28)
    Action TypeAGONIST
    Mechanism of actionAgonist of MRGPRX2;Agonist of SST 1 receptor;Agonist of SST 2 receptor;Agonist of SST 3 receptor;Agonist of SST 4 receptor;Agonist of SST 5 receptor

    Associated Targets(Human)

    SSTR1 Tclin Somatostatin receptor type 1 (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
    SSTR2 Tclin Somatostatin receptor type 2 (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
    SSTR3 Tclin Somatostatin receptor type 3 (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
    SSTR4 Tclin Somatostatin receptor type 4 (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
    SSTR5 Tclin Somatostatin receptor type 5 (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
    MRGPRX2 Tchem Mas-related G-protein coupled receptor member X2 (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

    Product Specifications

    Storage TempStore at -20°C,Desiccated
    Shipped InIce chest + Ice pads
    CAS74315-46-1(free)

    Certificates

    Certificate of Analysis(COA)

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    Genetic information

    Reference
    • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
    • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
    • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
    • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
    • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
    • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
    • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
    • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
    • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
    • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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