SP-13786 - 97%, high purity , CAS No.1448440-52-5

  • ≥97%
Item Number
S174266
Grouped product items
SKUSizeAvailabilityPrice Qty
S174266-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$201.90
S174266-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$297.90
S174266-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$501.90
S174266-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$724.90
S174266-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,016.90
View related series
FAP inhibitor

Basic Description

SynonymsAKOS027423971 | EX-A2803 | N-[2-[(2S)-2-Cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-4-quinolinecarboxamide | ZB1498 | S0842 | PUOOCZVRHBHJRS-NSHDSACASA-N | A908213 | AC-36275 | SB19734 | DTXSID401131123 | (S)-N-[2-(2-Cyano-4,4-difluoro-1-pyrrolidinyl)-
Specifications & Purity≥97%
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice

Associated Targets(Human)

FAP Tchem Prolyl endopeptidase FAP (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DPP7 Tchem Dipeptidyl peptidase II (2000 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DPP9 Tchem Dipeptidyl peptidase IX (1624 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MRC5 (9203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FAP Tchem Fibroblast activation protein alpha (827 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver (3974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

DPP4 Dipeptidyl peptidase IV (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PREP Prolyl endopeptidase (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fap Seprase (241 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasma (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
INCHI InChI=1S/C17H14F2N4O2/c18-17(19)7-11(8-20)23(10-17)15(24)9-22-16(25)13-5-6-21-14-4-2-1-3-12(13)14/h1-6,11H,7,9-10H2,(H,22,25)/t11-/m0/s1
InChi Key PUOOCZVRHBHJRS-NSHDSACASA-N
Canonical SMILES C1C(N(CC1(F)F)C(=O)CNC(=O)C2=CC=NC3=CC=CC=C23)C#N
Isomeric SMILES C1[C@H](N(CC1(F)F)C(=O)CNC(=O)C2=CC=NC3=CC=CC=C23)C#N
PubChem CID 71621488
Molecular Weight 344.32

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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10 results found

Lot NumberCertificate TypeDateItem
H2414325Certificate of AnalysisApr 30, 2024 S174266
H2414326Certificate of AnalysisApr 30, 2024 S174266
H2414327Certificate of AnalysisApr 30, 2024 S174266
H2414328Certificate of AnalysisApr 30, 2024 S174266
H2414329Certificate of AnalysisApr 30, 2024 S174266
H2414330Certificate of AnalysisApr 30, 2024 S174266
H2414331Certificate of AnalysisApr 30, 2024 S174266
H2414332Certificate of AnalysisApr 30, 2024 S174266
H2414333Certificate of AnalysisApr 30, 2024 S174266
H2414334Certificate of AnalysisApr 30, 2024 S174266

Chemical and Physical Properties

SolubilityDMSO: 100 mg/mL (290.43 mM), Sonification is recommended.

Related Documents

Citations of This Product

1. Haiyan Hong, Zhihao Zha, Ruiyue Zhao, Yang Luo, Wenbin Jin, Linlin Li, Ran Wang, Li Yan, Hui Wang, Karl Ploessl, Jinping Qiao, Lin Zhu, Hank F. Kung.  (2023)  [68Ga]Ga-HBED-CC-FAPI Derivatives with Improved Radiolabeling and Specific Tumor Uptake.  MOLECULAR PHARMACEUTICS,  20  (4): (2159–2169).  [PMID:36942924] [10.1021/acs.molpharmaceut.2c01112]

References

1. Haiyan Hong, Zhihao Zha, Ruiyue Zhao, Yang Luo, Wenbin Jin, Linlin Li, Ran Wang, Li Yan, Hui Wang, Karl Ploessl, Jinping Qiao, Lin Zhu, Hank F. Kung.  (2023)  [68Ga]Ga-HBED-CC-FAPI Derivatives with Improved Radiolabeling and Specific Tumor Uptake.  MOLECULAR PHARMACEUTICS,  20  (4): (2159–2169).  [PMID:36942924] [10.1021/acs.molpharmaceut.2c01112]

Solution Calculators