Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S166799-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $59.90 | |
S166799-10mg | 10mg | In stock | $75.90 | |
S166799-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $171.90 | |
S166799-50mg | 50mg | In stock | $271.90 | |
S166799-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $489.90 | |
S166799-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,102.90 |
Discover Spautin-1 by Aladdin Scientific in 98% (HPLC) for only $59.90. Available - in Ligands at Aladdin Scientific. Cell-permeable USP10 and USP13 inhibitor Tags: .
Synonyms | Spautin-1|1262888-28-7|6-Fluoro-N-(4-fluorobenzyl)quinazolin-4-amine|Spautin 1|6-fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine|CHEMBL2391504|MFCD16962292|6-Fluoro-N-[(4-Fluorophenyl)methyl]-4-quinazolinamine|4-Quinazolinamine, 6-fluoro-N-[(4-fluorop |
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Specifications & Purity | 98% (HPLC) |
Storage Temp | Store at -20°C,Argon charged |
Shipped In | Dry ice |
Product Description | Product Application: Spautin-1 has been used as an autophagy inhibitor:
to study its effects on vascular, glial, and neuronal alterations in the oxygen-induced retinopathy mouse model;
to evaluate its pre-treatment effect on the response of canine osteosarcoma cells to doxorubicin;
to study its effects on the production of interleukin (IL)-6 by oxidatively stressed dendritic cells (OS-DCs) in Luminex assay. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 6-fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine |
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INCHI | InChI=1S/C15H11F2N3/c16-11-3-1-10(2-4-11)8-18-15-13-7-12(17)5-6-14(13)19-9-20-15/h1-7,9H,8H2,(H,18,19,20) |
InChi Key | AWIVHRPYFSSVOG-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1CNC2=NC=NC3=C2C=C(C=C3)F)F |
Isomeric SMILES | C1=CC(=CC=C1CNC2=NC=NC3=C2C=C(C=C3)F)F |
WGK Germany | 3 |
PubChem CID | 51037431 |
Molecular Weight | 271.26 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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J2119649 | Certificate of Analysis | Aug 09, 2024 | S166799 |
J2119654 | Certificate of Analysis | Aug 09, 2024 | S166799 |
J2119656 | Certificate of Analysis | Aug 09, 2024 | S166799 |
D2318442 | Certificate of Analysis | Aug 26, 2021 | S166799 |
G2430006 | Certificate of Analysis | Aug 26, 2021 | S166799 |
Sensitivity | heat & air sensitive |
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Melt Point(°C) | 211 °C |
Pictogram(s) | GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H302:Harmful if swallowed H318:Causes serious eye damage |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. |
WGK Germany | 3 |