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Spautin-1 - 98% (HPLC), high purity , CAS No.1262888-28-7

  • ≥98%(HPLC)
Item Number
S166799
Grouped product items
SKUSizeAvailabilityPrice Qty
S166799-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
S166799-10mg
10mg
In stock
$75.90
S166799-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$171.90
S166799-50mg
50mg
In stock
$271.90
S166799-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$489.90
S166799-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,102.90

Discover Spautin-1 by Aladdin Scientific in 98% (HPLC) for only $59.90. Available - in Ligands at Aladdin Scientific. Cell-permeable USP10 and USP13 inhibitor Tags: .

Basic Description

SynonymsSpautin-1|1262888-28-7|6-Fluoro-N-(4-fluorobenzyl)quinazolin-4-amine|Spautin 1|6-fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine|CHEMBL2391504|MFCD16962292|6-Fluoro-N-[(4-Fluorophenyl)methyl]-4-quinazolinamine|4-Quinazolinamine, 6-fluoro-N-[(4-fluorop
Specifications & Purity98% (HPLC)
Storage TempStore at -20°C,Argon charged
Shipped InDry ice
Product Description

Product Application:

Spautin-1 has been used as an autophagy inhibitor: to study its effects on vascular, glial, and neuronal alterations in the oxygen-induced retinopathy mouse model; to evaluate its pre-treatment effect on the response of canine osteosarcoma cells to doxorubicin; to study its effects on the production of interleukin (IL)-6 by oxidatively stressed dendritic cells (OS-DCs) in Luminex assay.

Associated Targets

USP13 Tchem Ubiquitin carboxyl-terminal hydrolase 13 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

USP10 Tchem Ubiquitin carboxyl-terminal hydrolase 10 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 6-fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine
INCHI InChI=1S/C15H11F2N3/c16-11-3-1-10(2-4-11)8-18-15-13-7-12(17)5-6-14(13)19-9-20-15/h1-7,9H,8H2,(H,18,19,20)
InChi Key AWIVHRPYFSSVOG-UHFFFAOYSA-N
Canonical SMILES C1=CC(=CC=C1CNC2=NC=NC3=C2C=C(C=C3)F)F
Isomeric SMILES C1=CC(=CC=C1CNC2=NC=NC3=C2C=C(C=C3)F)F
WGK Germany 3
PubChem CID 51037431
Molecular Weight 271.26

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

5 results found

Lot NumberCertificate TypeDateItem
J2119649Certificate of AnalysisAug 09, 2024 S166799
J2119654Certificate of AnalysisAug 09, 2024 S166799
J2119656Certificate of AnalysisAug 09, 2024 S166799
D2318442Certificate of AnalysisAug 26, 2021 S166799
G2430006Certificate of AnalysisAug 26, 2021 S166799

Chemical and Physical Properties

Sensitivityheat & air sensitive
Melt Point(°C)211 °C

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07
Signal Danger
Hazard Statements

H302:Harmful if swallowed

H318:Causes serious eye damage

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

WGK Germany 3

Related Documents

Solution Calculators