Spironolactone - ≥97 %, high purity , Mineralocorticoid receptor antagonist, CAS No.52-01-7, Mineralocorticoid receptor antagonist

Item Number

S303875

• Synonyms: 3'-(3-Oxo-7-alpha-acetylthio-17-beta-hydroxyandrost-4-en-17-beta-yl)propionic acid lactone | DTXCID4014186 | S-((7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene
• Specifications & Purity: Moligand™, ≥97%
• Biochemical and Physiological Mechanisms: Mineralocorticoid receptor antagonist (IC 50 values are 24 and 77 nM at mineralocorticoid and androgen receptors respectively). Inhibits aldosterone binding to Mineralocorticoid receptor. Prevents sodium reabsorption. Active in vivo .
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: ANTAGONIST
• Mechanism of action: Mineralocorticoid receptor antagonist
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.