Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S288539-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 | |
S288539-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $119.90 | |
S288539-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $229.90 | |
S288539-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $369.90 | |
S288539-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $599.90 |
Potent α2Cantagonist
Synonyms | NCGC00015908-08 | NSC 665322 | Spiroxatrine [INN] | Espiroxatrina [INN-Spanish] | L001271 | Q6592066 | DR0QR50ALL | CCG-205216 | DTXCID1025198 | R-5188 | Tox21_110260_1 | CAS-1054-88-2 | DTXSID3045198 | SCHEMBL23326247 | 8-(2,3-Dihydro-1,4-benzodioxin-2-y |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | 5-HT1Aantagonist. More active and selective than spiperone. Also a very potentα2Cadrenergic receptor antagonist. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST, ANTAGONIST |
Mechanism of action | Agonist of 5-HT 1A receptor;Antagonist of 5-HT 2B receptor;Antagonist of α 1A-adrenoceptor;Antagonist of α 1B-adrenoceptor;Antagonist of α 1D-adrenoceptor;Antagonist of α 2A-adrenoceptor;Antagonist of α 2B-adrenoceptor;Antagonist of α 2C-adrenoceptor |
Product Description | 5-HT1A antagonist and α2C adrenergic receptor antagonist |
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IUPAC Name | 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
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INCHI | InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26) |
InChi Key | JVGBTTIJPBFLTE-UHFFFAOYSA-N |
Canonical SMILES | C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CC4COC5=CC=CC=C5O4 |
Isomeric SMILES | C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CC4COC5=CC=CC=C5O4 |
PubChem CID | 5268 |
Molecular Weight | 379.46 |
PubChem CID | 5268 |
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Wikipedia | Spiroxatrine |
ChEMBL Ligand | CHEMBL300555 |
BindingDB Ligand | 50020192 |
CAS Registry No. | 1054-88-2 |
GPCRdb Ligand | spiroxatrine |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
A2422358 | Certificate of Analysis | Dec 18, 2023 | S288539 |
A2422359 | Certificate of Analysis | Dec 18, 2023 | S288539 |
A2422360 | Certificate of Analysis | Dec 18, 2023 | S288539 |
A2422361 | Certificate of Analysis | Dec 18, 2023 | S288539 |
A2422362 | Certificate of Analysis | Dec 18, 2023 | S288539 |
A2422363 | Certificate of Analysis | Dec 18, 2023 | S288539 |
A2422364 | Certificate of Analysis | Dec 18, 2023 | S288539 |
A2422365 | Certificate of Analysis | Dec 18, 2023 | S288539 |
A2422366 | Certificate of Analysis | Dec 18, 2023 | S288539 |
A2422367 | Certificate of Analysis | Dec 18, 2023 | S288539 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 3.79, Max Conc. mM: 10 |
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