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sPLA2 inhibitor - 95%, high purity , CAS No.393569-31-8, Inhibitor of sPLA 2-2A

Moligand™

≥95%

CAS#: 393569-31-8
Formula: C₃₁H₃₇NO₄
Molecular Weight: 487.63
PubChem CID: 446400

Item Number

S339610

Grouped product items
SKU	Size	Availability	Price	Qty
S339610-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$379.90
S339610-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$919.90

an inhibitor of phospholipase A2

View related series

Metabolic Enzyme/Protease Phospholipase sPLA2-2A Inhibitor

Basic Description

Synonyms	sPLA2 inhibitor 1 \| KH064 \| KH-064 \| (4S)-4-(7-phenylheptanoylamino)-5-(4-phenylmethoxyphenyl)pentanoic acid \| 1j1a \| hnpsPLA2-IIa Inhibitor, 2b \| BDBM82331 \| HY-11059 \| (4S)-4-(7-phenylheptanoylamino)-5-[4-(phenylmethoxy)phenyl]pentanoic acid \| AKOS04074
Specifications & Purity	Moligand™, ≥95%
Storage Temp	Protected from light,Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of sPLA 2-2A
Product Description	sPLA2 inhibitor is a potent secretory Phospholipase A2 (sPLA2; Group IIa) inhibitor. The compuond is also a potent antiinflammatory agent and apoptosis inducer of lung cancer cells.

Associated Targets(Human)

PLA2G2A Tchem Phospholipase A2, membrane associated (1 Activities)

Discover Target: PLA2G2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HEK293 (82097 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(4S)-4-(7-phenylheptanoylamino)-5-(4-phenylmethoxyphenyl)pentanoic acid
INCHI	InChI=1S/C31H37NO4/c33-30(16-10-2-1-5-11-25-12-6-3-7-13-25)32-28(19-22-31(34)35)23-26-17-20-29(21-18-26)36-24-27-14-8-4-9-15-27/h3-4,6-9,12-15,17-18,20-21,28H,1-2,5,10-11,16,19,22-24H2,(H,32,33)(H,34,35)/t28-/m0/s1
InChi Key	KWLUIYFCMHKLKY-NDEPHWFRSA-N
Canonical SMILES	C1=CC=C(C=C1)CCCCCCC(=O)NC(CCC(=O)O)CC2=CC=C(C=C2)OCC3=CC=CC=C3
Isomeric SMILES	C1=CC=C(C=C1)CCCCCCC(=O)N[C@@H](CCC(=O)O)CC2=CC=C(C=C2)OCC3=CC=CC=C3
WGK Germany	3
Alternate CAS	393569-31-8
PubChem CID	446400
Molecular Weight	487.63

Solubility

Soluble in DMSO: >20 mg/mL

Sensitivity

Moisture & light sensitive

WGK Germany

RIDADR

NONHforallmodesoftransport

References

1. Hansford KA, Reid RC, Clark CI, Tyndall JD, Whitehouse MW, Guthrie T, McGeary RP, Schafer K, Martin JL, Fairlie DP. (2003) D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity.. Chembiochem, 4 (2-3): (181-5). [PMID:12616631] [10.1021/op500134e]

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sPLA2 inhibitor - 95%, high purity , CAS No.393569-31-8, Inhibitor of sPLA 2-2A

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

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