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sPLA2 inhibitor - 95%, high purity , CAS No.393569-31-8, Inhibitor of sPLA 2-2A

Moligand™

≥95%

CAS#: 393569-31-8
Formula: C₃₁H₃₇NO₄
Molecular Weight: 487.63
PubChem CID: 446400

Item Number

S339610

Grouped product items
SKU	Size	Availability	Price	Qty
S339610-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$379.90
S339610-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$919.90

an inhibitor of phospholipase A2

View related series

sPLA2-2A Inhibitor

Basic Description

Synonyms	sPLA2 inhibitor 1 \| KH064 \| KH-064 \| (4S)-4-(7-phenylheptanoylamino)-5-(4-phenylmethoxyphenyl)pentanoic acid \| 1j1a \| hnpsPLA2-IIa Inhibitor, 2b \| BDBM82331 \| HY-11059 \| (4S)-4-(7-phenylheptanoylamino)-5-[4-(phenylmethoxy)phenyl]pentanoic acid \| AKOS04074
Specifications & Purity	Moligand™, ≥95%
Storage Temp	Protected from light,Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of sPLA 2-2A
Product Description	sPLA2 inhibitor is a potent secretory Phospholipase A2 (sPLA2; Group IIa) inhibitor. The compuond is also a potent antiinflammatory agent and apoptosis inducer of lung cancer cells.

Associated Targets(Human)

PLA2G2A Tchem Phospholipase A2, membrane associated (1 Activities)

Discover Target: PLA2G2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HEK293 (82097 Activities)

Discover Target:

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TRPM2 Tchem Transient receptor potential cation channel subfamily M member 2 (348 Activities)

Discover Target: TRPM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(4S)-4-(7-phenylheptanoylamino)-5-(4-phenylmethoxyphenyl)pentanoic acid
INCHI	InChI=1S/C31H37NO4/c33-30(16-10-2-1-5-11-25-12-6-3-7-13-25)32-28(19-22-31(34)35)23-26-17-20-29(21-18-26)36-24-27-14-8-4-9-15-27/h3-4,6-9,12-15,17-18,20-21,28H,1-2,5,10-11,16,19,22-24H2,(H,32,33)(H,34,35)/t28-/m0/s1
InChi Key	KWLUIYFCMHKLKY-NDEPHWFRSA-N
Canonical SMILES	C1=CC=C(C=C1)CCCCCCC(=O)NC(CCC(=O)O)CC2=CC=C(C=C2)OCC3=CC=CC=C3
Isomeric SMILES	C1=CC=C(C=C1)CCCCCCC(=O)N[C@@H](CCC(=O)O)CC2=CC=C(C=C2)OCC3=CC=CC=C3
WGK Germany	3
Alternate CAS	393569-31-8
PubChem CID	446400
Molecular Weight	487.63

Solubility

Soluble in DMSO: >20 mg/mL

Sensitivity

Moisture & light sensitive

WGK Germany

RIDADR

NONHforallmodesoftransport

References

1. Hansford KA, Reid RC, Clark CI, Tyndall JD, Whitehouse MW, Guthrie T, McGeary RP, Schafer K, Martin JL, Fairlie DP. (2003) D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity.. Chembiochem, 4 (2-3): (181-5). [PMID:12616631]

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sPLA2 inhibitor - 95%, high purity , CAS No.393569-31-8, Inhibitor of sPLA 2-2A

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

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