The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
SR 141716A - 98%, high purity , CAS No.158681-13-1, Antagonist of CB 1 receptor;Antagonist of GPR55
Selective CB1inverse agonist
Basic Description Synonyms Rimonabant hydrochloride|158681-13-1|Rimonabant HCl|Rimonabant (Hydrochloride)|SR 141716A|5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide hydrochloride|5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1- Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms Potent and selective cannabinoid CB1receptor antagonist (Ki= 1.98 nM). Also acts as an inverse agonist reversing adenylyl cyclase inhibition byWIN 55,212-2 (IC50= 48 nM). Displays no activity at CB2receptors. Reduces food intake and body weight in orally Storage Temp Store at -20°C,Desiccated Shipped In Ice chest + Ice pads Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of CB 1 receptor;Antagonist of GPR55
Names and Identifiers IUPAC Name 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide;hydrochloride INCHI InChI=1S/C22H21Cl3N4O.ClH/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15;/h5-10,13H,2-4,11-12H2,1H3,(H,27,30);1H InChi Key REOYOKXLUFHOBV-UHFFFAOYSA-N Canonical SMILES CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)Cl.Cl Isomeric SMILES CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)Cl.Cl WGK Germany 3 PubChem CID 104849 Molecular Weight 500.25
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 50.02, Max Conc. mM: 100；DMSO (Slightly), Methanol (Slightly)
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS07 Signal Danger Hazard Statements H319: Causes serious eye irritation
H301: Toxic if swallowed
Precautionary Statements P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P337+P317: If eye irritation persists: Get medical help.
WGK Germany 3 RIDADR UN28116.1/PGIII
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
F2208389