Src Inhibitor-1 - ≥98%(HPLC), high purity , CAS No.179248-59-0, Inhibitor of receptor interacting serine/threonine kinase 2

Item Number

D135775

• Synonyms: SKI-1 | Src-l1 | Q27088870 | HY-101053 | Src I1 | EX-A1230 | 4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)- | HMS3678E03 | Src Inhibitor-1 | GTPL6042 | BRD-K50495309-001-01-2 | 6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine | Src Kinase Inhibi
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: Potent, selective and dual site Src family tyrosine kinase inhibitor (IC 50 values are 44 and 88 nM for Src and Lck, respectively). Cell-permeable, reversible and ATP-competitive. Interacts with both ATP and peptide-binding sites.
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of receptor interacting serine/threonine kinase 2
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Src kinase inhibitor I is a 4-anilinoquinazole competitive inhibitor of Src family tryosine kinases. Src kinase inhibitor I is a dual site inhibitor, described to compete at both the ATP and peptide binding sites of the kinase.
Src Inhibitor-1 may be used in Src kinase-mediated cell signaling studies.