SRT1720 HCl - ≥98%, high purity , CAS No.1001645-58-4

Item Number

S129890

Grouped product items
SKU	Size	Availability	Price
S129890-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$34.90
S129890-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$134.90
S129890-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$249.90
S129890-50mg	50mg	In stock	$559.90
S129890-250mg	250mg	In stock	$1,399.90

SIRT1 activator

Basic Description

Synonyms	SRT 1720 Hydrochloride \| BCP01774 \| SRT-1720, SRT1720 \| FT-0761472 \| SRT1720 xHydrochloride \| SCHEMBL16372055 \| J-523315 \| SRT1720 \| DTXSID80649411 \| J-000057 \| N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide hydr
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	SRT1720 is an NAD-dependent deacetylase sirtuin-1 (SIRT1) activator (EC50 = 0.16 μM), highly selective for SIRT1 over SIRT2 or SIRT3. Studies in yeast suggest that sirtuins may be involved in epigentic gene silencing and deactylation of proteins that regu
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Note	Refer to SDS for further information Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3. A selective SIRT1 activator

Names and Identifiers

IUPAC Name	N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide;hydrochloride
INCHI	InChI=1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31;/h1-8,13,15-16,26H,9-12,14H2,(H,29,33);1H
InChi Key	DTGRRMPPXCRRIM-UHFFFAOYSA-N
Canonical SMILES	C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl
Isomeric SMILES	C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl
PubChem CID	25232708
Molecular Weight	506.02

Certificates

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4 results found

Lot Number	Certificate Type	Date	Item
H2206170	Certificate of Analysis	May 11, 2024	S129890
H2206171	Certificate of Analysis	May 10, 2024	S129890
A2403354	Certificate of Analysis	Dec 09, 2023	S129890
H1503060	Certificate of Analysis	Mar 16, 2023	S129890

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Basic Description