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StAR Antibody - Primary antibody, specific to STAR, Rabbit IgG

  • Azide Free
  • Carrier Free
  • ExactAb™
  • High performance
  • Validated
  • Lot by Lot
Features and benefits
  • Short Overview:

    pAb; Rabbit anti Human StAR Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse,Pig,Rat
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab129336
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab129336-10μl
10μl
In stock
$69.90
Ab129336-50μl
50μl
In stock
$199.90
Ab129336-100μl
100μl
In stock
$309.90
Ab129336-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,599.90

pAb; Rabbit anti Human StAR Antibody; WB, IHC; Unconjugated

View related series
Accession#:P49675 Gene ID:6770

Basic Description

Product NameStAR Antibody - Primary antibody, specific to STAR, Rabbit IgG
SynonymsStAR|StARD1|START domain-containing protein 1
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, High performance, Lot by Lot
Host speciesRabbit
SpecificitySTAR
ImmunogenRecombinant STAR expressed in E.coli (AA 1-285)
Positive ControlWB: Recombinant Human STAR, Porcine adrenal gland, Rat adrenal gland lysates. IHC: Human kidney tissue.
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, High performance, Validated
Product Description

Rabbit anti Human StAR Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 0.01-2µg/mL
IHC: 5-20µg/mL
Protein Function
Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen affinity purified + Protein A purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

StAR Antibody (Ab129336) - Western Blot
All lanes: StAR Antibody (Ab129336) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 32 kDa
Observed band size: 28 kDa
Exposure time: 20.0 s

StAR Antibody (Ab129336) - IHC
DAB staining on IHC
Samples: Human Kidney Tissue
Primary Ab: 20 μg/mL StAR Antibody (Ab129336)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Associated Targets

STAR Tbio Steroidogenic acute regulatory protein, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IHC

5-20 µg/mL

WB

0.01-2 µg/mL

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404457Certificate of AnalysisApr 11, 2024 Ab129336
ZJ24F0404458Certificate of AnalysisApr 11, 2024 Ab129336
ZJ24F0404459Certificate of AnalysisApr 11, 2024 Ab129336

Related Documents

References

1. J F Strauss,C B Kallen,L K Christenson,H Watari,L Devoto,F Arakane,M Kiriakidou,T Sugawara.  (1999-11-05)  The steroidogenic acute regulatory protein (StAR): a window into the complexities of intracellular cholesterol trafficking..  Recent progress in hormone research,  54  (369-394).  [PMID:10548884]
2. Sugawara, T T and 6 more authors..  (1995)  Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity..  Biochemistry,    (3):   [PMID:7547998]
3. Gradi, A A and 5 more authors..  (1995)  The human steroidogenic acute regulatory (StAR) gene is expressed in the urogenital system and encodes a mitochondrial polypeptide..  Biochimica et biophysica acta,    (5):   [PMID:7548191]
4. Sugawara, T T and 9 more authors..  (1995)  Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13..  Proceedings of the National Academy of Sciences of the United States of America,    (23):   [PMID:7761400]
5. Lin, D D and 7 more authors..  (1995)  Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis..  Science (New York, N.Y.),    (24):   [PMID:7892608]
6. .  (1996)  The pathophysiology and genetics of congenital lipoid adrenal hyperplasia..  The New England journal of medicine,    (19):   [PMID:8948562]
7. Nakae, J J and 17 more authors..  (1997)  Analysis of the steroidogenic acute regulatory protein (StAR) gene in Japanese patients with congenital lipoid adrenal hyperplasia..  Human molecular genetics,      [PMID:9097960]
8. Katsumata, N N and 7 more authors..  (1998)  Novel frameshift mutation 840delA and a novel polymorphism D203A in the steroidogenic acute regulatory protein gene in a Japanese patient with congenital lipoid adrenal hyperplasia..  Human mutation,      [PMID:9452116]
9. Katsumata, N N and 6 more authors..  (1999)  A novel compound heterozygous mutation in the steroidogenic acute regulatory protein gene in a patient with congenital lipoid adrenal hyperplasia..  The Journal of clinical endocrinology and metabolism,      [PMID:10566637]
10. Thorsell, Ann-Gerd AG and 8 more authors..  (2011)  Comparative structural analysis of lipid binding START domains..  PloS one,      [PMID:21738568]

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