1.Kortylewski M, Kujawski M, Wang T, Wei S, Zhang S, Pilon-Thomas S, Niu G, Kay H, Mulé J, Kerr WG et al.. (2005) Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity.. Nat Med, 11 (12):(1314-21). [PMID:16288283]
2.Yuan J, Zhang F, Niu R. (2015) Multiple regulation pathways and pivotal biological functions of STAT3 in cancer.. Sci Rep, 5 (3):(17663). [PMID:26631279]
3.Yu H, Lee H, Herrmann A, Buettner R, Jove R. (2014) Revisiting STAT3 signalling in cancer: new and unexpected biological functions.. Nat Rev Cancer, 14 (11):(736-46). [PMID:25342631]
4.Jonker DJ, Nott L, Yoshino T, Gill S, Shapiro J, Ohtsu A, Zalcberg J, Vickers MM, Wei AC, Gao Y et al.. (2018) Napabucasin versus placebo in refractory advanced colorectal cancer: a randomised phase 3 trial.. Lancet Gastroenterol Hepatol, 3 (4):(263-270). [PMID:29397354]
5.Li C, Chen C, An Q, Yang T, Sang Z, Yang Y, Ju Y, Tong A, Luo Y. (2019) A novel series of napabucasin derivatives as orally active inhibitors of signal transducer and activator of transcription 3 (STAT3).. Eur J Med Chem, 162 (3):(543-554). [PMID:30472602]
6.Hubbard JM, Grothey A. (2017) Napabucasin: An Update on the First-in-Class Cancer Stemness Inhibitor.. Drugs, 77 (10):(1091-1103). [PMID:28573435]
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