Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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S129783-200mg | 200mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $10.90 | |
S129783-1g | 1g | In stock | $38.90 | |
S129783-5g | 5g | In stock | $125.90 | |
S129783-25g | 25g | In stock | $564.90 | |
S129783-100g | 100g | In stock | $2,031.90 |
Thymidine analog. Reverse-transcriptase inhibitor.
Synonyms | BO9LE4QFZF | Zerit(TM) | 3'-Deoxy-2'-thymidinene | ddeTyd | HMS3259L21 | HMS3428C07 | 1-((2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione | 2',3'-Didehydro-3'-deoxythymidine | 3'-deoxythymidin-2'-ene | HMS3039O05 | Stav |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | 3'-Deoxy-2',3'-didehydrothymidine is a HIV-1 RT (HIV reverse transcriptase) inhibitor that causes a consistent and rapid shortening of telomeres in Tetrahymera. 3'-Deoxy-2',3'-didehydrothymidine has been shown to decrease the proliferative activity of Jur |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Action Type | INHIBITOR |
Mechanism of action | Human immunodeficiency virus type 1 reverse transcriptase inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Stavudine (d4T) is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV. |
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Pubchem Sid | 488182454 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488182454 |
IUPAC Name | 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4-dione |
INCHI | InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1 |
InChi Key | XNKLLVCARDGLGL-JGVFFNPUSA-N |
Canonical SMILES | CC1=CN(C(=O)NC1=O)C2C=CC(O2)CO |
Isomeric SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C=C[C@H](O2)CO |
WGK Germany | 2 |
RTECS | XP2075000 |
PubChem CID | 18283 |
Molecular Weight | 224.21 |
Reaxy-Rn | 618327 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
J2111530 | Certificate of Analysis | Jul 10, 2023 | S129783 |
J2111617 | Certificate of Analysis | Jul 10, 2023 | S129783 |
J2111646 | Certificate of Analysis | Jul 10, 2023 | S129783 |
L1713089 | Certificate of Analysis | May 11, 2023 | S129783 |
G2301485 | Certificate of Analysis | Dec 09, 2022 | S129783 |
G2301489 | Certificate of Analysis | Dec 09, 2022 | S129783 |
G2301492 | Certificate of Analysis | Dec 09, 2022 | S129783 |
G2301493 | Certificate of Analysis | Dec 09, 2022 | S129783 |
G2301496 | Certificate of Analysis | Dec 09, 2022 | S129783 |
G2301499 | Certificate of Analysis | Dec 09, 2022 | S129783 |
G2301500 | Certificate of Analysis | Dec 09, 2022 | S129783 |
Solubility | Soluble in DMSO, methanol, water (83 mg/ml) at 23 °C, chloroform, ethanol, and propylene glycol (30 mg/mL) at 23 °C. |
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Specific Rotation[α] | -46° (C=0.69,H2O) |
Melt Point(°C) | 166°C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H341:Suspected of causing genetic defects H302:Harmful if swallowed H372:Causes damage to organs through prolonged or repeated exposure H361:Suspected of damaging fertility or the unborn child H362:May cause harm to breast-fed children |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P263:Avoid contact during pregnancy/while nursing. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
RTECS | XP2075000 |
Reaxy-Rn | 618327 |
Starting at $49.90
1. Peijun Chai, Xuhui Geng, Ruirui Zhu, Wenpu Wu, Xuesong Wang, Jinhua Li, Longwen Fu, Hongdan Wang, Wanhui Liu, Lingxin Chen, Zhihua Song. (2023) Fabrication and application of molecularly imprinted polymer doped carbon dots coated silica stationary phase. ANALYTICA CHIMICA ACTA, 1275 (341611). [PMID:37524474] |
2. Junping Xue, Jingxiu Zhang, Cuichi Yu, Maryam Arabi, Jinhua Li, Guisheng Li, Gangqiang Yang, Lingxin Chen, Zhihua Song. (2023) Synthesis and evaluation of ginsenosides imprinted polymer-based chromatographic stationary phase. JOURNAL OF SEPARATION SCIENCE, 46 (10): (2200825). [PMID:36892410] |
3. Zhihua Song, Yanqin Song, Yinghao Wang, Jinqiu Liu, Yumeng Wang, Wen Lin, Yaqi Wang, Jinhua Li, Jiping Ma, Gangqiang Yang, Lingxin Chen. (2022) Chromatographic performance of zidovudine imprinted polymers coated silica stationary phases. TALANTA, 239 (123115). [PMID:34890940] |
4. Lei Xu, Jing Lu, Weiqi Meng, Fengjuan Cui. (2021) Determination of the Nucleoside Reverse Transcriptase Inhibitors Lamivudine, Stavudine, and Didanosine in Human Urine by Micellar Electrokinetic Chromatography Using the Ionic Liquid-Based Cationic Surfactant 1-Tetradecyl-3-Methylimidazolium Bromide. ANALYTICAL LETTERS, [PMID:] |
1. Peijun Chai, Xuhui Geng, Ruirui Zhu, Wenpu Wu, Xuesong Wang, Jinhua Li, Longwen Fu, Hongdan Wang, Wanhui Liu, Lingxin Chen, Zhihua Song. (2023) Fabrication and application of molecularly imprinted polymer doped carbon dots coated silica stationary phase. ANALYTICA CHIMICA ACTA, 1275 (341611). [PMID:37524474] |
2. Junping Xue, Jingxiu Zhang, Cuichi Yu, Maryam Arabi, Jinhua Li, Guisheng Li, Gangqiang Yang, Lingxin Chen, Zhihua Song. (2023) Synthesis and evaluation of ginsenosides imprinted polymer-based chromatographic stationary phase. JOURNAL OF SEPARATION SCIENCE, 46 (10): (2200825). [PMID:36892410] |
3. Zhihua Song, Yanqin Song, Yinghao Wang, Jinqiu Liu, Yumeng Wang, Wen Lin, Yaqi Wang, Jinhua Li, Jiping Ma, Gangqiang Yang, Lingxin Chen. (2022) Chromatographic performance of zidovudine imprinted polymers coated silica stationary phases. TALANTA, 239 (123115). [PMID:34890940] |
4. Lei Xu, Jing Lu, Weiqi Meng, Fengjuan Cui. (2021) Determination of the Nucleoside Reverse Transcriptase Inhibitors Lamivudine, Stavudine, and Didanosine in Human Urine by Micellar Electrokinetic Chromatography Using the Ionic Liquid-Based Cationic Surfactant 1-Tetradecyl-3-Methylimidazolium Bromide. ANALYTICAL LETTERS, [PMID:] |