Skip to the beginning of the images gallery

Styrene oxide - 98%, high purity , CAS No.96-09-3

≥98%

CAS#: 96-09-3
Formula: C₈H₈O
Molecular Weight: 120.15
Beilstein Registry Number: 108582
EC Number: 202-476-7
MDL number: MFCD00005121
PubChem CID: 7276

Item Number

S106990

Grouped product items
SKU	Size	Availability	Price
S106990-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$9.90
S106990-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$24.90
S106990-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$44.90

View related series

Ethylene oxide Halogen free heterocyclic block

Basic Description

Synonyms	Styrene oxide\|2-Phenyloxirane\|96-09-3\|Phenyloxirane\|1,2-Epoxyethylbenzene\|Epoxystyrene\|Phenylethylene oxide\|Oxirane, phenyl-\|Styrene epoxide\|Styryl oxide\|Phenethylene oxide\|Styrene 7,8-oxide\|1-Phenyloxirane\|Styreneoxide\|Phenyl oxirane\|(Epoxyethyl)benzene\|
Specifications & Purity	≥98%
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice

Associated Targets

FBP1 Tchem Fructose-1,6-bisphosphatase 1 0 Activities

Discover Target: FBP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TSHR Tclin Thyrotropin receptor 0 Activities

Discover Target: TSHR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Discover Target: APEX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GSTM1 Tbio Glutathione S-transferase Mu 1 0 Activities

Discover Target: GSTM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-phenyloxirane
INCHI	InChI=1S/C8H8O/c1-2-4-7(5-3-1)8-6-9-8/h1-5,8H,6H2
InChi Key	AWMVMTVKBNGEAK-UHFFFAOYSA-N
Canonical SMILES	C1C(O1)C2=CC=CC=C2
Isomeric SMILES	C1C(O1)C2=CC=CC=C2
WGK Germany	3
RTECS	CZ9625000
PubChem CID	7276
UN Number	2810
Packing Group	I
Molecular Weight	120.15
Beilstein	108582
Reaxy-Rn	108582

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

19 results found

Lot Number	Certificate Type	Date	Item
K22171019	Certificate of Analysis	Aug 21, 2024	S106990
I2409222	Certificate of Analysis	Jul 09, 2024	S106990
I2409221	Certificate of Analysis	Jul 09, 2024	S106990
C2429756	Certificate of Analysis	Mar 12, 2024	S106990
C2429757	Certificate of Analysis	Mar 12, 2024	S106990
J2120578	Certificate of Analysis	Jul 11, 2023	S106990
G2306113	Certificate of Analysis	Apr 14, 2023	S106990
H2328044	Certificate of Analysis	Apr 14, 2023	S106990
F2406028	Certificate of Analysis	Apr 14, 2023	S106990
D2328179	Certificate of Analysis	Apr 14, 2023	S106990
D2328161	Certificate of Analysis	Apr 14, 2023	S106990
D2328154	Certificate of Analysis	Apr 14, 2023	S106990
D2328082	Certificate of Analysis	Apr 14, 2023	S106990
K2217952	Certificate of Analysis	Aug 12, 2022	S106990
K2217953	Certificate of Analysis	Aug 12, 2022	S106990
K2217969	Certificate of Analysis	Aug 12, 2022	S106990
C2221032	Certificate of Analysis	Apr 26, 2022	S106990
H2203075	Certificate of Analysis	Apr 26, 2022	S106990
D23061288	Certificate of Analysis	Apr 26, 2022	S106990

Chemical and Physical Properties

Solubility	Soluble in water.
Sensitivity	Air and moisture sensitive
Refractive Index	1.533-1.536
Flash Point(°F)	165.2 °F
Flash Point(°C)	77℃
Boil Point(°C)	194°C
Melt Point(°C)	-37°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H319:Causes serious eye irritation H312:Harmful in contact with skin H350:May cause cancer
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help.
WGK Germany	3
RTECS	CZ9625000
Reaxy-Rn	108582
Class	6.1

Alternative Products

References

1. Kingston AE, Lowndes J, Evans N, Clark B, Tomlinson R, Burnett JP, Mayne NG, Cockerham SL, Lodge D. (1998) Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines.. Neuropharmacology, 37 (3): (277-87). [PMID:9681926]
2. K J Koller,J T Coyle. (1985-11-01) The characterization of the specific binding of [3H]-N-acetylaspartylglutamate to rat brain membranes.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 5 ((11)): (2882-2888). [PMID:2865340]
3. L Birolo,E Sandmeier,P Christen,R A John. (1995-09-15) The roles of Tyr70 and Tyr225 in aspartate aminotransferase assessed by analysing the effects of mutations on the multiple reactions of the substrate analogue serine o-sulphate.. European journal of biochemistry, 232 ((3)): (859-864). [PMID:7588727]
4. D H Phillips,P B Farmer. (1994-01-01) Evidence for DNA and protein binding by styrene and styrene oxide.. Critical reviews in toxicology, 24 Suppl (S35-S46). [PMID:7818770]
5. E E McConnell,J A Swenberg. (1994-01-01) Review of styrene and styrene oxide long-term animal studies.. Critical reviews in toxicology, 24 Suppl (S49-S55). [PMID:7818772]
6. E E McConnell,J A Swenberg. (1993-01-01) Styrene and styrene oxide: results of studies on carcinogenicity in experimental animals.. IARC scientific publications, ((127)): (323-333). [PMID:8070879]
7. G J Wang,H J Chung,J Schnuer,K Pratt,A C Zable,M P Kavanaugh,P A Rosenberg. (1998-01-28) High affinity glutamate transport in rat cortical neurons in culture.. Molecular pharmacology, 53 ((1)): (88-96). [PMID:9443935]
8. R J Vandenberg,A D Mitrovic,G A Johnston. (1998-05-30) Serine-O-sulphate transport by the human glutamate transporter, EAAT2.. British journal of pharmacology, 123 ((8)): (1593-1600). [PMID:9605566]
9. R Panizzutti,J De Miranda,C S Ribeiro,S Engelender,H Wolosker. (2001-04-20) A new strategy to decrease N-methyl-D-aspartate (NMDA) receptor coactivation: inhibition of D-serine synthesis by converting serine racemase into an eliminase.. Proceedings of the National Academy of Sciences of the United States of America, 98 ((9)): (5294-5299). [PMID:11309496]
10. Yasuyuki Sadzuka,Yasuyo Yamashita,Takashi Sonobe. (2002-12-11) Effects of glutamate transporter inhibitors on the antitumor activity of doxorubicin.. Clinical cancer research : an official journal of the American Association for Cancer Research, 8 ((12)): (3943-3947). [PMID:12473610]
11. Elena Fumagalli,Marcella Funicello,Thomas Rauen,Marco Gobbi,Tiziana Mennini. (2007-11-27) Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1.. European journal of pharmacology, 578 ((2-3)): (171-176). [PMID:18036519]
12. Chizuru Nagayoshi,Matsujiro Ishibashi,Masao Tokunaga. (2009-02-10) Purification and characterization of human brain serine racemase expressed in moderately halophilic bacteria.. Protein and peptide letters, 16 ((2)): (201-206). [PMID:19200045]
13. Shuangjun Lin,Geoffrey P Horsman,Ben Shen. (2010-08-14) Characterization of the epoxide hydrolase NcsF2 from the neocarzinostatin biosynthetic gene cluster.. Organic letters, 12 ((17)): (3816-3819). [PMID:20704329]
14. Alessandra Lattanzi,Alessio Russo,Paola Rizzo,Guglielmo Monaco,Riccardo Zanasi. (2010-11-03) Absolute configuration assignment of (3-phenyloxirane-2,2-diyl)bis(phenylmethanone) via density functional calculations of optical rotation and vibrational circular dichroism.. Chirality, 22 Suppl 1 (E130-E135). [PMID:21038383]
15. Gary P Carlson. (2010-11-09) Metabolism and toxicity of styrene in microsomal epoxide hydrolase-deficient mice.. Journal of toxicology and environmental health. Part A, 73 ((24)): (1689-1699). [PMID:21058172]
16. Gary P Carlson. (2011-01-29) Comparison of styrene oxide enantiomers for hepatotoxic and pneumotoxic effects in microsomal epoxide hydrolase-deficient mice.. Journal of toxicology and environmental health. Part A, 74 ((6)): (347-350). [PMID:21271435]
17. Filippo Maria Perna,Antonio Salomone,Mariangela Dammacco,Saverio Florio,Vito Capriati. (2011-05-28) Solvent and TMEDA effects on the configurational stability of chiral lithiated aryloxiranes.. Chemistry (Weinheim an der Bergstrasse, Germany), 17 ((29)): (8216-8225). [PMID:21618297]
18. Gary P Carlson. (2011-07-14) Hepatotoxicity and pneumotoxicity of styrene and its metabolites in glutathione S-transferase-deficient mice.. Drug and chemical toxicology, 34 ((4)): (440-444). [PMID:21749217]
19. David M Hodgson,Stanislav Man. (2011-07-19) Synthesis of the anti-HIV agent (-)-hyperolactone C by using oxonium ylide formation-rearrangement.. Chemistry (Weinheim an der Bergstrasse, Germany), 17 ((35)): (9731-9737). [PMID:21766363]
20. Michael Kotik,Alain Archelas,Veronika Faměrová,Pavla Oubrechtová,Vladimír Křen. (2011-08-23) Laboratory evolution of an epoxide hydrolase - towards an enantioconvergent biocatalyst.. Journal of biotechnology, 156 ((1)): (1-10). [PMID:21854816]
21. . (2011-08-25) Styrene-7,8-oxide.. Report on carcinogens : carcinogen profiles, 12 (391-392). [PMID:21863098]
22. G Cruzan,J Bus,J Hotchkiss,J Harkema,M Banton,S Sarang. (2011-11-02) CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced mouse lung tumors.. Regulatory toxicology and pharmacology : RTP, 62 ((1)): (214-220). [PMID:22041433]
23. Feng Yu,Ji-Ning Zhou,Xi-Chang Zhang,Yao-Zong Sui,Fei-Fei Wu,Lin-Jie Xie,Albert S C Chan,Jing Wu. (2011-11-09) Copper(II)-catalyzed hydrosilylation of ketones using chiral dipyridylphosphane ligands: highly enantioselective synthesis of valuable alcohols.. Chemistry (Weinheim an der Bergstrasse, Germany), 17 ((50)): (14234-14240). [PMID:22065457]
24. Wen-Jing Chen,Wen-Yong Lou,Min-Hua Zong. (2011-11-22) Efficient asymmetric hydrolysis of styrene oxide catalyzed by Mung bean epoxide hydrolases in ionic liquid-based biphasic systems.. Bioresource technology, 115 (58-62). [PMID:22100235]
25. Deniz Yildirim,S Seyhan Tükel,Dilek Alagöz,Ozlem Alptekin. (2011-12-07) Preparative-scale kinetic resolution of racemic styrene oxide by immobilized epoxide hydrolase.. Enzyme and microbial technology, 49 ((6-7)): (555-559). [PMID:22142731]
26. Michael R Paillasse,Nathalie Saffon,Heinz Gornitzka,Sandrine Silvente-Poirot,Marc Poirot,Philippe de Medina. (2012-01-31) Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles.. Journal of lipid research, 53 ((4)): (718-725). [PMID:22285872]
27. Gary P Carlson. (2012-03-06) Modification of the metabolism and toxicity of styrene and styrene oxide in hepatic cytochrome P450 reductase deficient mice and CYP2F2 deficient mice.. Toxicology, 294 ((2-3)): (104-108). [PMID:22386858]
28. Frédéric Cosnier,Hervé Nunge,Benoît Cossec,Laurent Gaté. (2012-04-12) Simultaneous determination of aromatic acid metabolites of styrene and styrene-oxide in rat urine by gas chromatography-flame ionization detection.. Journal of analytical toxicology, 36 ((5)): (312-318). [PMID:22492963]
29. Michel Oelschlägel,Janosch A D Gröning,Dirk Tischler,Stefan R Kaschabek,Michael Schlömann. (2012-04-17) Styrene oxide isomerase of Rhodococcus opacus 1CP, a highly stable and considerably active enzyme.. Applied and environmental microbiology, 78 ((12)): (4330-4337). [PMID:22504818]
30. Laurent Gaté,Jean-Claude Micillino,Sylvie Sébillaud,Cristina Langlais,Frédéric Cosnier,Hervé Nunge,Christian Darne,Yves Guichard,Stéphane Binet. (2012-04-18) Genotoxicity of styrene-7,8-oxide and styrene in Fisher 344 rats: a 4-week inhalation study.. Toxicology letters, 211 ((3)): (211-219). [PMID:22507543]
31. Daniel Kuhn,Bruno Bühler,Andreas Schmid. (2012-04-25) Production host selection for asymmetric styrene epoxidation: Escherichia coli vs. solvent-tolerant Pseudomonas.. Journal of industrial microbiology & biotechnology, 39 ((8)): (1125-1133). [PMID:22526330]
32. Günter Speit,Regina Linsenmeyer,Petra Schütz,Stefanie Kuehner. (2012-08-08) Insensitivity of the in vitro cytokinesis-block micronucleus assay with human lymphocytes for the detection of DNA damage present at the start of the cell culture.. Mutagenesis, 27 ((6)): (743-747). [PMID:22869611]
33. Rainer Gross,Katja Buehler,Andreas Schmid. (2012-08-14) Engineered catalytic biofilms for continuous large scale production of n-octanol and (S)-styrene oxide.. Biotechnology and bioengineering, 110 ((2)): (424-436). [PMID:22886684]
34. Wen-Jing Chen,Wen-Yong Lou,Chun-Yang Yu,Hong Wu,Min-Hua Zong,Thomas J Smith. (2012-09-22) Use of hydrophilic ionic liquids in a two-phase system to improve Mung bean epoxide hydrolases-mediated asymmetric hydrolysis of styrene oxide.. Journal of biotechnology, 162 ((2-3)): (183-190). [PMID:22995740]
35. Guang-Peng Wu,Donald J Darensbourg,Xiao-Bing Lu. (2012-09-29) Tandem metal-coordination copolymerization and organocatalytic ring-opening polymerization via water to synthesize diblock copolymers of styrene oxide/CO2 and lactide.. Journal of the American Chemical Society, 134 ((42)): (17739-17745). [PMID:23016983]
36. Jung-Hee Woo,Tae-Hyung Kwon,Jun-Tae Kim,Choong-Gon Kim,Eun Yeol Lee. (2012-12-18) Identification and characterization of epoxide hydrolase activity of polycyclic aromatic hydrocarbon-degrading bacteria for biocatalytic resolution of racemic styrene oxide and styrene oxide derivatives.. Biotechnology letters, 35 ((4)): (599-606). [PMID:23242500]
37. W Dieb,A Hafidi. (2013-07-25) Astrocytes are involved in trigeminal dynamic mechanical allodynia: potential role of D-serine.. Journal of dental research, 92 ((9)): (808-813). [PMID:23881719]
38. Son T Nguyen, Steven M Kwasny, Xiaoyuan Ding, Steven C Cardinale, Courtney T McCarthy, Hong-Suk Kim, Hiroshi Nikaido, Norton P Peet, John D Williams, Terry L Bowlin, Timothy J Opperman,. (2015-03-31) Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.. Bioorganic & medicinal chemistry, 23 ((9)): ( 2024-2034 ). [PMID:25818767]
39. Jonathan Collins,Marcel Grund,Christoph Brandenbusch,Gabriele Sadowski,Andreas Schmid,Bruno Bühler. (2015-04-29) The dynamic influence of cells on the formation of stable emulsions in organic-aqueous biotransformations.. Journal of industrial microbiology & biotechnology, 42 ((7)): (1011-1026). [PMID:25916765]
40. Kai Wu, Hualei Wang, Huihui Sun, Dongzhi Wei,. (2015-06-20) Efficient kinetic resolution of phenyl glycidyl ether by a novel epoxide hydrolase from Tsukamurella paurometabola.. Applied microbiology and biotechnology, 99 ((22)): ( 9511-9521 ). [PMID:26088175]
41. Takashi Toyao,Mika Fujiwaki,Kenta Miyahara,Tae-Ho Kim,Yu Horiuchi,Masaya Matsuoka. (2015-09-24) Design of Zeolitic Imidazolate Framework Derived Nitrogen-Doped Nanoporous Carbons Containing Metal Species for Carbon Dioxide Fixation Reactions.. ChemSusChem, 8 ((22)): (3905-3912). [PMID:26395673]
42. R Barale. (1991-03-01) The genetic toxicology of styrene and styrene oxide.. Mutation research, 257 ((2)): (107-126). [PMID:2005936]
43. J Kunert. (1985-01-01) Metabolism of sulfur-containing amino acids in the dermatophyte Microsporum gypseum. II. Acidic amino acid derivatives.. Journal of basic microbiology, 25 ((2)): (111-118). [PMID:3925121]
44. A Arnone,P H Rogers,C C Hyde,M W Makinen,R Feldhaus,C M Metzler,D E Metzler. (1984-01-01) Crystallographic and chemical studies on cytosolic aspartate aminotransferase.. Progress in clinical and biological research, 144B (171-193). [PMID:6425857]
45. J J Likos,H Ueno,R W Feldhaus,D E Metzler. (1982-08-31) A novel reaction of the coenzyme of glutamate decarboxylase with L-serine O-sulfate.. Biochemistry, 21 ((18)): (4377-4386). [PMID:6812624]
46. H Ueno,J J Likos,D E Metzler. (1982-08-31) Chemistry of the inactivation of cytosolic aspartate aminotransferase by serine O-sulfate.. Biochemistry, 21 ((18)): (4387-4393). [PMID:6812625]
47. R Contestabile,R A John. (1996-08-15) The mechanism of high-yielding chiral syntheses catalysed by wild-type and mutant forms of aspartate aminotransferase.. European journal of biochemistry, 240 ((1)): (150-155). [PMID:8797848]
48. A D Mitrovic,S G Amara,G A Johnston,R J Vandenberg. (1998-06-17) Identification of functional domains of the human glutamate transporters EAAT1 and EAAT2.. The Journal of biological chemistry, 273 ((24)): (14698-14706). [PMID:9614067]
49. G A Kimmich,J Roussie,M Manglapus,J Randles. (2001-06-27) Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1.. The Journal of membrane biology, 182 ((1)): (17-30). [PMID:11426296]
50. Lorraine Brennan,Paula M Alves,Chandralal Hewage,J Paul G Malthouse,Gethin J McBean. (2006-02-07) Impact of the gliotoxin L-serine-O-sulphate on cellular metabolism in cultured rat astrocytes.. Neurochemistry international, 48 ((8)): (739-745). [PMID:16458390]
51. Jan Volmer,Christoph Neumann,Bruno Bühler,Andreas Schmid. (2014-08-17) Engineering of Pseudomonas taiwanensis VLB120 for constitutive solvent tolerance and increased specific styrene epoxidation activity.. Applied and environmental microbiology, 80 ((20)): (6539-6548). [PMID:25128338]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.