1H-Pyrrole-3-carboxamide, 5-((5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-N-((2S)-2-hydroxy-3-(4-morpholinyl)propyl)-2,4-dimethyl- , Tyrosine-protein kinase receptor FLT3 inhibitor, CAS No.452105-23-6, Tyrosine-protein kinase receptor FLT3 inhibitor

Item Number

H671079

Grouped product items
SKU	Size	Availability	Price
H671079-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$89.90
H671079-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$349.90
H671079-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$559.90
H671079-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$899.90

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Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	SU14813 (SU 014813) is a multi receptor tyrosine kinase inhibitor with IC50 values of 50 nM, 2 nM, 4 nM, and 15 nM for VEGFR2, VEGFR1, PDGFR β, and Kit (c-Kit), respectively. SU14813 has strong anti angiogenic and anti-tumor activity.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	INHIBITOR
Mechanism of action	Tyrosine-protein kinase receptor FLT3 inhibitor

Names and Identifiers

IUPAC Name	5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
INCHI	InChI=1S/C23H27FN4O4/c1-13-20(10-18-17-9-15(24)3-4-19(17)27-22(18)30)26-14(2)21(13)23(31)25-11-16(29)12-28-5-7-32-8-6-28/h3-4,9-10,16,26,29H,5-8,11-12H2,1-2H3,(H,25,31)(H,27,30)/b18-10-/t16-/m0/s1
InChi Key	CTNPALGJUAXMMC-PMFHANACSA-N
Canonical SMILES	CC1=C(NC(=C1C(=O)NCC(CN2CCOCC2)O)C)C=C3C4=C(C=CC(=C4)F)NC3=O
Isomeric SMILES	CC1=C(NC(=C1C(=O)NC[C@@H](CN2CCOCC2)O)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O
PubChem CID	10138259
Molecular Weight	442.48

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Basic Description