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SU 4984 - ≥98%, high purity , CAS No.186610-89-9
an Flg tyrosine kinase inhibitor
Basic Description Specifications & Purity ≥98% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description SU 4984 is an inhibitor of tyrosine kinase activity of fibroblast growth factor receptor 1 (Flg). SU 4984 also inhibits αFGF-induced tyrosine phosphorylation of ERK1 and ERK2 and the tyrosine phosphorylation of the PDGF receptor and the insulin receptors. it does not, however, inhibit the kinase activity of the EGF receptor.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 4-[4-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]phenyl]piperazine-1-carbaldehyde INCHI InChI=1S/C20H19N3O2/c24-14-22-9-11-23(12-10-22)16-7-5-15(6-8-16)13-18-17-3-1-2-4-19(17)21-20(18)25/h1-8,13-14H,9-12H2,(H,21,25)/b18-13- InChi Key ZNFJBJDODKHWED-AQTBWJFISA-N Canonical SMILES C1CN(CCN1C=O)C2=CC=C(C=C2)C=C3C4=CC=CC=C4NC3=O Isomeric SMILES C1CN(CCN1C=O)C2=CC=C(C=C2)/C=C\3/C4=CC=CC=C4NC3=O PubChem CID 5941540 Molecular Weight 333.38
Chemical and Physical Properties Solubility Soluble in DMSO (25 mg/ml), and acetone. Refractive Index n20D1.72 (Predicted) Boil Point(°C) 649.12° C at 760 mmHg (Predicted) Melt Point(°C) 237.06° C (Predicted)
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