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SU-5402 (DMSO solution) - 10mM in DMSO, high purity , CAS No.215543-92-3
Potent, selective VEGFR and FGFR inhibitor
Basic Description Synonyms 215543-92-3 | su5402 | SU-5402 | SU 5402 | 3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE | 3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid | 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3 Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms Potent, selective VEGFR and FGFR inhibitor (IC 50 values are 0.02 (VEGFR2), 0.03 (FGFR1), 0.51 (PDGFRβ) and >100 μM (EGFR)). Attenuates integrin β4-induced differentiation of neural stem cells. Shows antitumor effects in vivo. Also available as a solid ( Storage Temp Protected from light,Store at -80°C Shipped In Ice chest + Ice pads
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid INCHI InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8- InChi Key JNDVEAXZWJIOKB-JYRVWZFOSA-N Canonical SMILES CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O Isomeric SMILES CC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O WGK Germany 3 Alternate CAS 215543-92-3 PubChem CID 5289418 MeSH Entry Terms 3-((3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene)-2-inolinone;SU 5402;Su-5402;SU5402 Molecular Weight 296.32
Chemical and Physical Properties Sensitivity air and light sensitive
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