Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S288813-5mg | 5mg | In stock | $94.90 | |
S288813-10mg | 10mg | In stock | $171.90 | |
S288813-25mg | 25mg | In stock | $387.90 | |
S288813-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $1,393.90 | |
S288813-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,134.90 |
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
Specifications & Purity | Moligand™, ≥97% |
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Biochemical and Physiological Mechanisms | Potent ATP-competitive Src family kinase inhibitor (IC50values are 0.02, 0.13, 0.17, 0.28 and 6.88 nM for Yes, Lyn, Fyn, Src and Lck, respectively). Exhibits > 6.5 fold selectivity for Src family over other kinases. Also AMPK inhibitor (IC50= 0.22 μM for |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of aurora kinase B;Inhibitor of aurora kinase C;Inhibitor of BR serine/threonine kinase 2;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of LYN proto-oncogene; Src family tyrosine kinase;Inhibitor of SRC proto-oncogene; no |
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IUPAC Name | (3Z)-N,N-dimethyl-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indole-5-sulfonamide |
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INCHI | InChI=1S/C19H21N3O3S/c1-22(2)26(24,25)14-7-8-18-15(11-14)16(19(23)21-18)10-13-9-12-5-3-4-6-17(12)20-13/h7-11,20H,3-6H2,1-2H3,(H,21,23)/b16-10- |
InChi Key | LOGJQOUIVKBFGH-YBEGLDIGSA-N |
Canonical SMILES | CN(C)S(=O)(=O)C1=CC2=C(C=C1)NC(=O)C2=CC3=CC4=C(N3)CCCC4 |
Isomeric SMILES | CN(C)S(=O)(=O)C1=CC\2=C(C=C1)NC(=O)/C2=C\C3=CC4=C(N3)CCCC4 |
WGK Germany | 3 |
PubChem CID | 5312137 |
Molecular Weight | 371.45 |
PubChem CID | 5312137 |
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DrugBank Ligand | DB08039 |
ChEMBL Ligand | CHEMBL605003 |
CAS Registry No. | 330161-87-0 |
Wikipedia | SU6656 |
RCSB PDB Ligand | K88 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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K2108818 | Certificate of Analysis | Aug 20, 2024 | S288813 |
K2108820 | Certificate of Analysis | Aug 20, 2024 | S288813 |
K2108821 | Certificate of Analysis | Aug 20, 2024 | S288813 |
K2108822 | Certificate of Analysis | Aug 20, 2024 | S288813 |
K2108823 | Certificate of Analysis | Aug 20, 2024 | S288813 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 37.15, Max Conc. mM: 100 |
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Sensitivity | light sensitive |
WGK Germany | 3 |
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RIDADR | NONHforallmodesoftransport |