![Butanedioic Acid 1-[16,16-Bis(4-methoxyphenyl)-3,3-dioxido-7-oxo-16-phenyl-6,15-dioxa-3-thia-8-azahexadec-1-yl] Ester](https://media-prod.aladdinsci.com/media/catalog/product/cache/515ce11dbf2c7bc125424616eb49ad88/B/3/B354975.png)
Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | Butane diacid | CCG-266069 | Succinic acid, 99% | A 12084 | ADIPIC ACID IMPURITY B (EP IMPURITY) | Butandisaeure | AI3-06297 | ethylenesuccinic acid | STR02803 | Amber acid | LMFA01170043 | Sal succini | 1,2-Ethanedicarboxylate | 1,4-Butanedioate | Asucci |
|---|---|
| Specifications & Purity | Moligand™, for cell culture, for insect cell culture, ≥99%(T) |
| Shipped In | Normal |
| Grade | for cell culture, for insect cell culture, Moligand™ |
Associated Targets(Human)
SUCNR1 Tchem Succinate receptor 1 (0 Activities)
F2 Tclin Thrombin (11687 Activities)
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ESR1 Tclin Estrogen receptor alpha (17718 Activities)
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PGR Tclin Progesterone receptor (8562 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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AR Tclin Androgen Receptor (11781 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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MAOA Tclin Monoamine oxidase A (11911 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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DRD1 Tclin Dopamine D1 receptor (9720 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ACHE Tclin Acetylcholinesterase (18204 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SLC6A4 Tclin Serotonin transporter (12625 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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OPRM1 Tclin Mu opioid receptor (19785 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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DRD3 Tclin Dopamine D3 receptor (14368 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SLC6A3 Tclin Dopamine transporter (10535 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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KCNH2 Tclin HERG (29587 Activities)
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PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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HRH3 Tclin Histamine H3 receptor (10389 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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EGLN2 Tclin Hypoxia-inducible factor prolyl hydroxylase 1 (404 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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DCXR Tbio L-xylulose reductase (11 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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MDM2 Tchem p53-binding protein Mdm-2 (4545 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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EGLN1 Tclin Egl nine homolog 1 (1702 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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EGLN3 Tclin Egl nine homolog 3 (250 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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HIF1AN Tbio Hypoxia-inducible factor 1-alpha inhibitor (79 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ME3 Tbio NADP-dependent malic enzyme, mitochondrial (80 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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LMNA Tbio Prelamin-A/C (36751 Activities)
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SLC22A8 Tclin Solute carrier family 22 member 8 (241 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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FTO Tchem Alpha-ketoglutarate-dependent dioxygenase FTO (473 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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ALKBH5 Tchem RNA demethylase ALKBH5 (134 Activities)
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SLC13A3 Tbio Solute carrier family 13 member 3 (5 Activities)
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KDM5B Tchem Lysine-specific demethylase 5B (814 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
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HD1 Histone deacetylase (38 Activities)
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Saccharomyces cerevisiae (19171 Activities)
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Pichia kudriavzevii (7448 Activities)
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Candida albicans (78123 Activities)
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Artemia (698 Activities)
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Mus musculus (284745 Activities)
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Vero (26788 Activities)
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rep Replicase polyprotein 1ab (378 Activities)
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SARS-CoV-2 (38078 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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A085R Prolyl 4-hydroxylase (72 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | butanedioic acid |
|---|---|
| INCHI | InChI=1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8) |
| InChi Key | KDYFGRWQOYBRFD-UHFFFAOYSA-N |
| Canonical SMILES | C(CC(=O)O)C(=O)O |
| Isomeric SMILES | C(CC(=O)O)C(=O)O |
| WGK Germany | 1 |
| RTECS | WM4900000 |
| PubChem CID | 1110 |
| Molecular Weight | 118.09 |
| Beilstein | 1754069 |
| Reaxy-Rn | 1754069 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2310363 | Certificate of Analysis | Oct 26, 2023 | S108853 |
| F23131611 | Certificate of Analysis | Nov 05, 2022 | S108853 |
| F23131651 | Certificate of Analysis | Nov 05, 2022 | S108853 |
| F23131666 | Certificate of Analysis | Nov 05, 2022 | S108853 |
| F23131673 | Certificate of Analysis | Nov 05, 2022 | S108853 |
| F2207026 | Certificate of Analysis | Mar 21, 2022 | S108853 |
| F2207027 | Certificate of Analysis | Mar 21, 2022 | S108853 |
Chemical and Physical Properties
| Solubility | Soluble in water, slightly soluble in ethanol, ether, acetone, and glycerol. |
|---|---|
| Sensitivity | Moisture sensitive. |
| Flash Point(°F) | 206 °C |
| Flash Point(°C) | 402.8 °F |
| Boil Point(°C) | 235°C |
| Melt Point(°C) | 184-186°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS05, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H319:Causes serious eye irritation H318:Causes serious eye damage |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. |
| WGK Germany | 1 |
| RTECS | WM4900000 |
| Reaxy-Rn | 1754069 |
| Merck Index | 8869 |
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Citations of This Product
| 1. Li Yujia, Bi Erping. (2024) Influencing mechanisms of tartaric acid on adsorption and degradation of tetracycline on goethite: insight from solid and liquid aspects. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 31 (4): (6411-6424). [PMID:38148461] [10.1007/s11356-023-31465-w] |
| 2. Qi Chen, Ying Li, Kangling Yan, Guanghui Li, Donghui Luo, Weidong Bai, Xiaofang Zeng, Qingping Wu, Jinhua Deng, Hao Dong. (2024) Variations of volatile flavors and microbial communities in Chinese Chaozhou pickle during natural fermentation revealed by GC-IMS and high-throughput sequencing. LWT-FOOD SCIENCE AND TECHNOLOGY, 191 (115610). [PMID:] [10.1016/j.lwt.2023.115610] |
| 3. Bin Wang, Shizhen Dong, Xiaojuan Wu, Yanling Yu, Nuoxin Wang, Jinyang Li, Zuowan Zhou. (2024) Preparation of topologically defective carbons by atomic imprinting for catalyzing the chemical oxidative polymerization of 3-aminophenylboronic acid. CARBON, 216 (118594). [PMID:12475965] [10.1016/j.carbon.2023.118594] |
| 4. Xiaoming Zhou, Junwei Wu, Dongdong Yu. (2023) Study on tensile stress fluctuation of poly(butylene succinate) (PBS) and its bicrystalline block copolyesters (PBSEG). POLYMER ENGINEERING AND SCIENCE, [PMID:12665591] [10.1002/pen.26531] |
| 5. Tianbo Zhou, Xueshuai Wang, Yi Liu, Liuchun Zheng. (2023) A green and efficient synthetic strategy for the preparation of PBS ionomers with high molecular weight, high ionic group content and good combined properties. CHEMICAL ENGINEERING JOURNAL, 477 (1): (146275). [PMID:26337389] [10.1016/j.cej.2023.146275] |
| 6. Rong Yang, Chaoyi Cai, Zhifan Chen, Guoxiang Zou, Jinchun Li. (2023) The effect of dynamic vulcanization on the morphology and biodegradability of super toughened poly(lactic acid)/unsaturated poly(ether-ester) blends. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 253 (2): (126790). [PMID:37703967] [10.1016/j.ijbiomac.2023.126790] |
| 7. Han Hu, Chen Lin, Qingyang Luan, Xiaoyu Jiang, Xiaoqin Zhang, Qianfeng Wang, Yunxiao Dong, Jing Wei, Jinggang Wang, Jin Zhu. (2023) Synergistic Modification of PBT with Diglycolic Acid and Succinic Acid: Fast Crystallization and High Strength-Toughness Copolyesters for Environmentally Degradable Packaging. ACS Sustainable Chemistry & Engineering, 11 (38): (14068–14080). [PMID:23019224] [10.1021/acssuschemeng.3c03394] |
| 8. Yanru Zhang, Jingjing Zhang, Ying Wang, Yang Li, Jun He, Yanyan Wang, Longbo Zhang, Zhenpeng Wang, Qingli Qian, Buxing Han. (2023) Synthesis of Carboxylic Acids via Reaction of Ketones/Aldehydes with CO2 and H2. ORGANOMETALLICS, 42 (16): (2312–2318). [PMID:] [10.1021/acs.organomet.3c00294] |
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| 12. Yongtao Fei, Yuliang Wang, Zhichao Zhang, Jinglong Liang, Wenhong Zhao, Weidong Bai, Songgui He, Youqiang Liu. (2023) Effects of traditional starter and the Round-Koji-Maker starter on microbial communities and volatile flavours of Chi-Flavour Baijiu. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 58 (8): (4155-4170). [PMID:] [10.1111/ijfs.16495] |
| 13. Hu Yao, Xing Kequan, Li Xiaojing, Sang Shangyuan, McClements David Julian, Chen Long, Long Jie, Jiao Aiquan, Xu Xueming, Wang Jinpeng, Jin Zhengyu, Qiu Chao. (2023) Cyclodextrin carboxylate improves the stability and activity of nisin in a wider range of application conditions. npj Science of Food, 7 (1): (1-9). [PMID:37210414] [10.1038/s41538-023-00181-7] |
| 14. Huan Wang, Zhengzai Cheng, Lesly Dasilva Wandji Djouonkep, Linfeng Wang, Shuanpu Cai, Mario Gauthier. (2023) Synthesis and properties of biodegradable aliphatic–aromatic polyesters derived from 4-hydroxybenzaldehyde. JOURNAL OF APPLIED POLYMER SCIENCE, 140 (29): (e54063). [PMID:] [10.1002/app.54063] |
| 15. Jichun Zhao, Zhengwei Tan, Ruyu Zhang, Weizhou Li, Fuhua Li, Jian Ming. (2023) Effects of brine- and NaCl- fermented carrots on lipid metabolism and gut microbiota in high-fat diet-fed mice. Journal of Functional Foods, 105 (105564). [PMID:] [10.1016/j.jff.2023.105564] |
| 16. Heng Ye, Gang Wang, Xuchao Wang, Lin Wang, Wei Ni, Linjian Chen, Yifan Zhu, Longshan Zhao, Zhili Xiong, Yan Wang, Cuilian Dai, Binbin Liu. (2023) San-wei-tan-xiang capsule attenuates atherosclerosis by increasing lysosomal activity in adipose tissue macrophages. JOURNAL OF ETHNOPHARMACOLOGY, 312 (116444). [PMID:37061068] [10.1016/j.jep.2023.116444] |
| 17. Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) Development of an oil-sealed anaerobic fermentation process for high production of γ-aminobutyric acid with Lactobacillus brevis isolated by directional colorimetric screening. BIOCHEMICAL ENGINEERING JOURNAL, 194 (108893). [PMID:] [10.1016/j.bej.2023.108893] |
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| 20. Jiawei Luo, Shan Xiao, Jihui Wang, Bo Wang, Yanxue Cai, Wenfeng Hu. (2023) The Metabolite Profiling and Microbial Community Dynamics during Pineapple By-Product Fermentation Using Co-Inoculation of Lactic Acid Bacteria and Yeast. Fermentation-Basel, 9 (2): (79). [PMID:] [10.3390/fermentation9020079] |
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