A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of Glukagon-like peptide-1 and glucose-dependent insulinotrophic peptide.
Storage Temp
Room temperature
Shipped In
Normal
Grade
JPE, Ph.Eur., pharmaceutical grade, PharmPure™
Product Description
Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production. As part of our EMPROVE ® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC ® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Sucralose is a high-intensity sweetener which is non-cariogenic and suitable for diabetics and patients with an impaired glucose tolerance. In addition, it is readily soluble and masks both bitterness and medicinal off-notes with equal ease – making it exceptionally well-suited for pharmaceutical applications. Our Sucralose is available in micronized or granular form, both pharmaceutical grade, allowing you to choose depending on your individual needs. Due to its optimal dispersion behavior, sucralose powder is typically recommended for solid dose formulations, while the fast dissolution behavior of sucralose granular makes it very well-suited for liquid formulations.
2.He Yue, Chen Jianshe, Shi Weiyao, Shi Jingang, Ma Tian, Wang Xinmiao. (2023) Can nonvolatile tastants be smelled during food oral processing?. CHEMICAL SENSES, 48 [PMID:37590987]
3.Zhang Yuntao, Liu Lin, Wei Chunbo, Wang Xuanyang, Li Ran, Xu Xiaoqing, Zhang Yingfeng, Geng Guannan, Dang Keke, Ming Zhu, Tao Xinmiao, Xu Huan, Yan Xuemin, Zhang Jia, Hu Jinxia, Li Ying. (2023) Vitamin K2 supplementation improves impaired glycemic homeostasis and insulin sensitivity for type 2 diabetes through gut microbiome and fecal metabolites. BMC Medicine, 21 (1):(1-16). [PMID:37147641]
4.Xue Mei, Wenchang Wang, Qingyi Li, Minxian Wu, Liyin Bu, Zhidong Chen. (2023) A novel electrochemical sensor based on gold nanobipyramids and poly-L-cysteine for the sensitive determination of trilobatin. ANALYST, 148 (10):(2335-2342). [PMID:37186001]
5.Xuejiao Zhang, Jiaxin Gu, Congying Zhao, Yaozhong Hu, Bowei Zhang, Jin Wang, Huan Lv, Xuemeng Ji, Shuo Wang. (2022) Sweeteners Maintain Epithelial Barrier Function Through the miR-15b/RECK/MMP-9 Axis, Remodel Microbial Homeostasis, and Attenuate Dextran Sodium Sulfate-Induced Colitis in Mice. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (1):(171–183). [PMID:34962394]
6.Xiaofeng Wei, Ying Chen, Shan He, Huiting Lian, Xuegong Cao, Bin Liu. (2021) L-histidine-regulated zeolitic imidazolate framework modified electrochemical interface for enantioselective determination of L-glutamate. ELECTROCHIMICA ACTA, 400 (139464). [PMID:]
2.He Yue, Chen Jianshe, Shi Weiyao, Shi Jingang, Ma Tian, Wang Xinmiao. (2023) Can nonvolatile tastants be smelled during food oral processing?. CHEMICAL SENSES, 48 [PMID:37590987]
3.Zhang Yuntao, Liu Lin, Wei Chunbo, Wang Xuanyang, Li Ran, Xu Xiaoqing, Zhang Yingfeng, Geng Guannan, Dang Keke, Ming Zhu, Tao Xinmiao, Xu Huan, Yan Xuemin, Zhang Jia, Hu Jinxia, Li Ying. (2023) Vitamin K2 supplementation improves impaired glycemic homeostasis and insulin sensitivity for type 2 diabetes through gut microbiome and fecal metabolites. BMC Medicine, 21 (1):(1-16). [PMID:37147641]
4.Xue Mei, Wenchang Wang, Qingyi Li, Minxian Wu, Liyin Bu, Zhidong Chen. (2023) A novel electrochemical sensor based on gold nanobipyramids and poly-L-cysteine for the sensitive determination of trilobatin. ANALYST, 148 (10):(2335-2342). [PMID:37186001]
5.Xuejiao Zhang, Jiaxin Gu, Congying Zhao, Yaozhong Hu, Bowei Zhang, Jin Wang, Huan Lv, Xuemeng Ji, Shuo Wang. (2022) Sweeteners Maintain Epithelial Barrier Function Through the miR-15b/RECK/MMP-9 Axis, Remodel Microbial Homeostasis, and Attenuate Dextran Sodium Sulfate-Induced Colitis in Mice. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (1):(171–183). [PMID:34962394]
6.Xiaofeng Wei, Ying Chen, Shan He, Huiting Lian, Xuegong Cao, Bin Liu. (2021) L-histidine-regulated zeolitic imidazolate framework modified electrochemical interface for enantioselective determination of L-glutamate. ELECTROCHIMICA ACTA, 400 (139464). [PMID:]
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