Grouped product items

SKU

Size

Availability

Price

Qty

S114289-250mg

250mg

Available within 4-8 weeks(?)

$102.90

Basic Description

Synonyms	sulfadimethoxine\|Sulphadimethoxine\|122-11-2\|Sulfadimethoxydiazine\|Albon\|Sulfadimethoxin\|Sulfadimetoxin\|Sulfadimetoxina\|Dimetazina\|Madribon\|Agribon\|Sulfadimethoxinum\|4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide\|4-amino-N-(2,6-dimethoxypyrimidi
Specifications & Purity	Moligand™, analytical standard
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	analytical standard, Moligand™

Product Properties

ALogP	1.6

Associated Targets

CTH Tchem Cystathionine gamma-lyase 0 Activities

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CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

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DRD2 Tclin D(2) dopamine receptor 0 Activities

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DRD4 Tchem D(4) dopamine receptor 0 Activities

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CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

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ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 0 Activities

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GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

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ELANE Tclin Neutrophil elastase 0 Activities

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EGFR Tclin Epidermal growth factor receptor 0 Activities

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AVPR1A Tclin Vasopressin V1a receptor 0 Activities

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HMGCR Tclin 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0 Activities

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HDAC6 Tclin Histone deacetylase 6 0 Activities

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HRH1 Tclin Histamine H1 receptor 0 Activities

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

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SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities

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SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

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SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 0 Activities

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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities

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CA2 Tclin Carbonic anhydrase 2 0 Activities

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DRD3 Tclin D(3) dopamine receptor 0 Activities

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KDR Tclin Vascular endothelial growth factor receptor 2 0 Activities

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CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities

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CHRM4 Tclin Muscarinic acetylcholine receptor M4 0 Activities

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ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities

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ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities

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HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

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ADORA2A Tclin Adenosine receptor A2a 0 Activities

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ACHE Tclin Acetylcholinesterase 0 Activities

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ADRA1B Tclin Alpha-1B adrenergic receptor 0 Activities

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ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities

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AR Tclin Androgen receptor 0 Activities

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MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities

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AKR1B1 Tclin Aldose reductase 0 Activities

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ADORA1 Tclin Adenosine receptor A1 0 Activities

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HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

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ADORA3 Tchem Adenosine receptor A3 0 Activities

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HTR6 Tchem 5-hydroxytryptamine receptor 6 0 Activities

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HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities

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F2 Tclin Prothrombin 0 Activities

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EDNRA Tclin Endothelin-1 receptor 0 Activities

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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities

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OPRD1 Tclin Delta-type opioid receptor 0 Activities

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OPRK1 Tclin Kappa-type opioid receptor 0 Activities

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OPRM1 Tclin Mu-type opioid receptor 0 Activities

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NOS2 Tchem Nitric oxide synthase, inducible 0 Activities

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TACR1 Tclin Substance-P receptor 0 Activities

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NOS1 Tchem Nitric oxide synthase, brain 0 Activities

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Names and Identifiers

IUPAC Name	4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
INCHI	InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChi Key	ZZORFUFYDOWNEF-UHFFFAOYSA-N
Canonical SMILES	COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC
Isomeric SMILES	COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC
WGK Germany	3
RTECS	WO9030000
PubChem CID	5323
Molecular Weight	310.33
Beilstein	306856

Database links

Antibiotic DB	2063
PubChem CID	5323
ChEMBL Ligand	CHEMBL62193
ChEBI	CHEBI:32161
DrugBank Ligand	DB06150
DrugCentral Ligand	2501
CAS Registry No.	122-11-2

Certificates

Certificate of Analysis(COA)

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1 results found

Lot Number	Certificate Type	Date	Item
L2214298	Certificate of Analysis	Sep 04, 2024	S114289

Chemical and Physical Properties

Melt Point(°C)	200°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H317:May cause an allergic skin reaction
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	WO9030000
Merck Index	8905

References

1. Bermingham A, Derrick JP. (2002) The folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery.. Bioessays, 24 (7): (637-48). [PMID:12111724]
2. Food and Drug Administration, HHS. (2016) Additions and Modifications to the List of Drug Products That Have Been Withdrawn or Removed From the Market for Reasons of Safety or Effectiveness. Final rule.. Fed Regist, 81 (195): (69668-77). [PMID:27731962]
3. Ovung A, Bhattacharyya J. (2021) Sulfonamide drugs: structure, antibacterial property, toxicity, and biophysical interactions.. Biophys Rev, 13 (2): (259-272). [PMID:33936318]
4. Achari A, Somers DO, Champness JN, Bryant PK, Rosemond J, Stammers DK. (1997) Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.. Nat Struct Biol, 4 (6): (490-7). [PMID:9187658]

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Sulfadimethoxine - analytical standard, high purity , CAS No.122-11-2