Grouped product items

SKU

Size

Availability

Price

Qty

S107128-25g

25g

In stock

$19.90

S107128-100g

100g

In stock

$68.90

S107128-500g

500g

Available within 4-8 weeks(?)

$106.90

Basic Description

Synonyms	sulfaguanidine\|57-67-0\|Sulphaguanidine\|Sulfaguanidin\|Sulfaguine\|Guanicil\|Sulfanilylguanidine\|Sulfanilguanidine\|Sulfoguanidine\|Sulfaguanil\|Sulfoguanil\|Sulfoguanyl\|Abiguanil\|Guanidan\|Sulfentidine\|Aterian\|Ganidan\|Guamide\|Orgaguanidon\|Sulfaguanidinum\|Sulfogue
Specifications & Purity	98%
Storage Temp	Protected from light
Shipped In	Normal
Grade	Moligand™

Associated Targets

F2 Tclin Prothrombin 1 Activities

Discover Target: F2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488179893
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488179893
IUPAC Name	2-(4-aminophenyl)sulfonylguanidine
INCHI	InChI=1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)
InChi Key	BRBKOPJOKNSWSG-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC=C1N)S(=O)(=O)N=C(N)N
Isomeric SMILES	C1=CC(=CC=C1N)S(=O)(=O)N=C(N)N
RTECS	WO8575000
PubChem CID	5324
Molecular Weight	214.24
Beilstein	5659891
Reaxy-Rn	747716

Database links

Antibiotic DB	2064
PubChem CID	5324
ChEMBL Ligand	CHEMBL338802
ChEBI	CHEBI:94621
DrugBank Ligand	DB13726
DrugCentral Ligand	2505
CAS Registry No.	57-67-0
PubChem SID	488179893

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot Number	Certificate Type	Date	Item
L2319082	Certificate of Analysis	Dec 25, 2023	S107128
L2308038	Certificate of Analysis	Dec 13, 2023	S107128
C1919003	Certificate of Analysis	Jan 11, 2023	S107128
D23261114	Certificate of Analysis	Jan 11, 2023	S107128
D23261124	Certificate of Analysis	Jan 11, 2023	S107128
F2307339	Certificate of Analysis	Jan 11, 2023	S107128
K2217245	Certificate of Analysis	Nov 19, 2022	S107128
G2212090	Certificate of Analysis	Jul 19, 2022	S107128

Chemical and Physical Properties

Solubility	Solubility in water: Practically insoluble; Slightly soluble in Alcohol; Insoluble in Ether
Sensitivity	Light sensitive.
Melt Point(°C)	190-193°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
RTECS	WO8575000
Reaxy-Rn	747716
Merck Index	8908

References

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3. Achari A, Somers DO, Champness JN, Bryant PK, Rosemond J, Stammers DK. (1997) Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.. Nat Struct Biol, 4 (6): (490-7). [PMID:9187658]
4. M Sanchez Pena,F Salinas,M C Mahedero,J J Aaron. (1992-10-01) Spectrofluorimetric determination of sulphonamides in pharmaceutical compounds and foods.. Journal of pharmaceutical and biomedical analysis, 10 ((10-12)): (805-808). [PMID:1298386]
5. K Nakanishi,M Masada,T Nadai. (1990-12-01) Improvement by adjuvants on the rectal bioavailability of non-absorbable drugs following administration of suppository.. Journal of pharmacobio-dynamics, 13 ((12)): (760-765). [PMID:2098548]
6. M Anees,F S Steven. (1994-01-01) Inhibition of a tumour protease with 3,4-dichloroisocoumarin, pentamidine-isethionate and guanidino derivatives.. Journal of enzyme inhibition, 8 ((3)): (213-221). [PMID:7539490]
7. L S Wan,W K Chui. (1995-07-01) Deviation of the ratio of drugs in a two-component mixture encapsulated in cellulose phthalate microspheres.. Journal of microencapsulation, 12 ((4)): (417-423). [PMID:8583316]
8. Y Yoshihashi,E Yonemochi,M Makita,S Yamamura,E Fukuoka,K Terada. (2000-03-08) Determination of hydration kinetics of sulfaguanidine anhydrate in aqueous solution by calorimetry.. Chemical & pharmaceutical bulletin, 48 ((2)): (208-210). [PMID:10705505]
9. Consolación de Frutos,Manuel de Barrio,Pilar Tornero,Ruth Barranco,Angel Rodríguez,María Rubio. (2002-05-10) Erythema multiforme from sulfaguanidine.. Contact dermatitis, 46 ((3)): (186-187). [PMID:12000336]
10. T W Wong,L W Chan,H Y Lee,P W S Heng. (2002-10-25) Release characteristics of pectin microspheres prepared by an emulsification technique.. Journal of microencapsulation, 19 ((4)): (511-522). [PMID:12396387]
11. A A F Wasfy,A A Aly. (2003-05-15) Simple synthesis of novel diphenylsulfapyrimidine acetates from chalcones and their antimicrobial activity.. Folia microbiologica, 48 ((1)): (51-55). [PMID:12744076]
12. Vimal K Balakrishnan,Ken A Terry,John Toito. (2006-08-02) Determination of sulfonamide antibiotics in wastewater: a comparison of solid phase microextraction and solid phase extraction methods.. Journal of chromatography. A, 1131 ((1-2)): (1-10). [PMID:16879830]
13. Alan D Gift,Lynne S Taylor. (2006-08-03) Hyphenation of Raman spectroscopy with gravimetric analysis to interrogate water-solid interactions in pharmaceutical systems.. Journal of pharmaceutical and biomedical analysis, 43 ((1)): (14-23). [PMID:16882458]
14. N Mora Diez,A Muñoz de la Peña,M C Mahedero García,D Bohoyo Gil,F Cañada-Cañada. (2007-03-30) Fluorimetric determination of sulphaguanidine and sulphamethoxazole by host-guest complexation in beta-cyclodextrin and partial least squares calibration.. Journal of fluorescence, 17 ((3)): (309-318). [PMID:17393284]
15. Anna Białk-Bielińska,Jolanta Kumirska,Richard Palavinskas,Piotr Stepnowski. (2009-10-20) Optimization of multiple reaction monitoring mode for the trace analysis of veterinary sulfonamides by LC-MS/MS.. Talanta, 80 ((2)): (947-953). [PMID:19836577]
16. Yanhua Cui,Hailing Zhang,Ying ma,Cuihong Dai,Jie Cui. (2010-08-24) [Synthesis and identification of artificial antigens for sulfaguanidine and sulfathiazole].. Wei sheng yan jiu = Journal of hygiene research, 39 ((4)): (440-443). [PMID:20726233]
17. Anna Białk-Bielińska,Joanna Maszkowska,Wojciech Mrozik,Agata Bielawska,Marta Kołodziejska,Richard Palavinskas,Piotr Stepnowski,Jolanta Kumirska. (2011-12-27) Sulfadimethoxine and sulfaguanidine: their sorption potential on natural soils.. Chemosphere, 86 ((10)): (1059-1065). [PMID:22197018]
18. Yong-Gang Zhao,Li-Xin Zhou,Sheng-Dong Pan,Ping-Ping Zhan,Xiao-Hong Chen,Mi-Cong Jin. (2014-05-02) Fast determination of 22 sulfonamides from chicken breast muscle using core-shell nanoring amino-functionalized superparamagnetic molecularly imprinted polymer followed by liquid chromatography-tandem mass spectrometry.. Journal of chromatography. A, 1345 (17-28). [PMID:24780256]
19. R W Han,N Zheng,Z N Yu,J Wang,X M Xu,X Y Qu,S L Li,Y D Zhang,J Q Wang. (2015-03-22) Simultaneous determination of 38 veterinary antibiotic residues in raw milk by UPLC-MS/MS.. Food chemistry, 181 (119-126). [PMID:25794729]
20. Chang-Er Chen,Hao Zhang,Guang-Guo Ying,Li-Jun Zhou,Kevin C Jones. (2015-10-10) Passive sampling: A cost-effective method for understanding antibiotic fate, behaviour and impact.. Environment international, 85 (284-291). [PMID:26451705]
21. V Saada,F Janssen,F Cottenot. (1990-01-01) [Toxidermatosis caused by sulfaguanidine].. Annales de dermatologie et de venereologie, 117 ((11)): (903-904). [PMID:2151594]
22. H Sasaki,M Kojima,J Nakamura,J Shibasaki. (1990-03-01) Enhancing effect of pyrrolidone derivatives on the transdermal penetration of sulfaguanidine, aminopyrine and Sudan III.. Journal of pharmacobio-dynamics, 13 ((3)): (200-205). [PMID:2374089]
23. B Beauvais,C Sarfati,S Challier,F Derouin. (1994-10-01) In vitro model to assess effect of antimicrobial agents on Encephalitozoon cuniculi.. Antimicrobial agents and chemotherapy, 38 ((10)): (2440-2448). [PMID:7840584]
24. J Arias,M Fernández-Rivas,M Martinez,C Senent. (1994-01-01) Fixed drug eruption caused by sulfaguanidine.. Dermatology (Basel, Switzerland), 189 ((2)): (196-197). [PMID:8075454]
25. F Villas Martínez,A Joral Badas,J F Garmendia Goitia,I Aguirre. (1994-02-01) Sensitization to oral enoxolone.. Contact dermatitis, 30 ((2)): (124-124). [PMID:8187501]
26. B W Clare,A Scozzafava,C T Supuran. (2001-08-11) Protease inhibitors, part 13: Specific, weakly basic thrombin inhibitors incorporating sulfonyl dicyandiamide moieties in their structure.. Journal of enzyme inhibition, 16 ((1)): (1-13). [PMID:11496831]
27. R F Cross,A M Smairl. (2001-10-12) Salt effects in capillary zone electrophoresis. V. Adsorption and retention of electrically neutral analytes.. Journal of chromatography. A, 929 ((1-2)): (113-121). [PMID:11594392]
28. S Kastalli,S El Aidli,R Daghfous,S Trabelsi,M Lakhal,M-H Loueslati,C Belkahia. (2004-07-20) [Fixed drug eruption induced by sulfaguanidine].. Annales de dermatologie et de venereologie, 131 ((4)): (382-384). [PMID:15258515]
29. Carmen M Sharaby. (2005-11-01) Preparation, characterization and biological activity of Fe(III), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and UO(2)(II) complexes of new cyclodiphosph(V)azane of sulfaguanidine.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 62 ((1-3)): (326-334). [PMID:16257733]
30. Alan D Gift,Paul E Luner,Laura Luedeman,Lynne S Taylor. (2009-05-21) Manipulating hydrate formation during high shear wet granulation using polymeric excipients.. Journal of pharmaceutical sciences, 98 ((12)): (4670-4683). [PMID:19455624]
31. Marco De Liguoro,Vincenzo Di Leva,Guglielmo Gallina,Elisabetta Faccio,Gabriele Pinto,Antonino Pollio. (2010-08-03) Evaluation of the aquatic toxicity of two veterinary sulfonamides using five test organisms.. Chemosphere, 81 ((6)): (788-793). [PMID:20673955]

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Sulfaguanidine - 98%, high purity , CAS No.57-67-0