Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S114298-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $55.90 | |
S114298-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $113.90 | |
S114298-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $271.90 |
Synonyms | KBio2_006767 | Lentac | Slosul | Altezol | DTXSID5023611 | Opera_ID_698 | SPBio_002587 | Sulfamethoxypyridazinum | DivK1c_000239 | Durox | Lederkyn | Smop | Sulfametoxipiridazina | 3-(4-Aminobenzenesulfonamido)-6-methoxypyridazine | KBio1_000239 | NCGC000 |
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Specifications & Purity | analytical standard |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | analytical standard |
Action Type | INHIBITOR |
Mechanism of action | Bacterial dihydropteroate synthase inhibitor |
ALogP | 0.3 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide |
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INCHI | InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15) |
InChi Key | VLYWMPOKSSWJAL-UHFFFAOYSA-N |
Canonical SMILES | COC1=NN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N |
Isomeric SMILES | COC1=NN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N |
WGK Germany | 2 |
RTECS | WP0400000 |
PubChem CID | 5330 |
Molecular Weight | 280.3 |
Beilstein | 277076 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
K2415586 | Certificate of Analysis | Jul 15, 2024 | S114298 |
K2415588 | Certificate of Analysis | Jul 15, 2024 | S114298 |
E2028099 | Certificate of Analysis | Dec 20, 2023 | S114298 |
A2006132 | Certificate of Analysis | Jul 13, 2023 | S114298 |
K2307098 | Certificate of Analysis | Jul 13, 2023 | S114298 |
K2307061 | Certificate of Analysis | Apr 13, 2022 | S114298 |
Melt Point(°C) | 180-183°C |
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Pictogram(s) | GHS08, GHS05, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H335:May cause respiratory irritation H318:Causes serious eye damage H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
WGK Germany | 2 |
RTECS | WP0400000 |
Merck Index | 8919 |
1. Jiana Lin, Zenghui Xie, Yuling Hu, Gongke Li, Qisheng Zhong. (2024) Flower-like calix[6]arene-based covalent organic framework for membrane extraction of sulfonamides in animal-derived food through host-guest interaction prior to determination with ultra-high performance liquid chromatography-tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY A, 1713 (11): (464499). [PMID:37983987] [10.1016/j.chroma.2023.464499] |
2. Jing Wang, Yong Zhang, Fubin Liu, Ying Liu, Litao Wang, Guihua Gao. (2023) Preparation of a Multifunctional and Multipurpose Chitosan/Cyclodextrin/MIL-68(Al) Foam Column and Examining Its Adsorption Properties for Anionic and Cationic Dyes and Sulfonamides. ACS Omega, 8 (35): (32017–32026). [PMID:37692232] [10.1021/acsomega.3c03897] |
3. Meiling Ping, Wenchao Lv, Chen Yang, Qian Chen, Zongwen Wang, Fengfu Fu. (2023) A Paper-Based Multicolor Colorimetric Aptasensor for the Visual Determination of Multiple Sulfonamides Based on Aptamer-Functionalized Magnetic Beads and NADH–Ascorbic Acid-Mediated Gold Nanobipyramids. Chemosensors, 11 (7): (386). [PMID:] [10.3390/chemosensors11070386] |
4. Zongwen Wang, Xiating Li, Feng Zhang, Yu Gao, Jintian Cheng, FengFu Fu. (2023) Regulating the Growth Rate of Gold Nanobipyramids via a HCl-NADH-Ascorbic Acid System toward a Dual-Channel Multicolor Colorimetric Immunoassay for Simultaneously Screening and Detecting Multiple Sulfonamides. ANALYTICAL CHEMISTRY, [PMID:37382204] [10.1021/acs.analchem.3c01928] |
5. Dai Yongheng, Yuan Huayu, Li Jiang, Su Qi, Yi Qianwen, Zhang Yuntao. (2023) Direct Z-scheme P–TiO2/g-C3N4 heterojunction for the photocatalytic degradation of sulfa antibiotics. RSC Advances, 13 (9): (5957-5969). [PMID:36816086] [10.1039/D2RA07289K] |
6. Tang Jiaming, Zheng Xiaoling, Jiang Shuang, Cao Mingdong, Wang Sixian, Zhou Zhaoyang, Nie Xunqing, Fang Yu, Le Tao. (2022) Dual fluorescent aptasensor for simultanous and quantitative detection of sulfadimethoxine and oxytetracycin residues in animal-derived foods tissues based on mesoporous silica. Frontiers in Nutrition, 9 [PMID:36618689] [10.3389/fnut.2022.1077893] |
7. Ligui Wu, Mingyu Wang, Lingling Rong, Wenbiao Wang, Linwei Chen, Qiaofeng Wu, Haoyu Sun, Xiangfeng Huang, Xiaoming Zou. (2024) Structural effects of sulfonamides on the proliferation dynamics of sulfonamide resistance genes in the sequencing batch reactors and the mechanism. Journal of Environmental Sciences, 135 (161). [PMID:37778792] [10.1016/j.jes.2022.11.014] |
8. Li Gang, Wu Ming-Huo, Liu Yan, Hu Yu-Feng. (2023) Facile fluorescent probe for simultaneous fluorescence detection of fluoroquinolones and copper. CHEMICAL PAPERS, 77 (3): (1423-1432). [PMID:] [10.1007/s11696-022-02568-4] |
9. Yawen Wang, Jingwen Huang, He Guo, Chendong Puyang, Jiangang Han, Yan Li, Yunxia Ruan. (2022) Mechanism and process of sulfamethoxazole decomposition with persulfate activated by pulse dielectric barrier discharge plasma. SEPARATION AND PURIFICATION TECHNOLOGY, 287 (120540). [PMID:] [10.1016/j.seppur.2022.120540] |
10. Yang Wang, Xueyan Liu, Lei Zhang. (2020) Assembling 3D hierarchical hollow flower-like Ni@N-doped graphitic carbon for boosting simultaneously efficient removal and sensitive monitoring of multiple sulfonamides. JOURNAL OF HAZARDOUS MATERIALS, 386 (121629). [PMID:31759760] [10.1016/j.jhazmat.2019.121629] |
11. Minghuo Wu, Lin Fu, Yufeng Hu, Jingyun Su, Siyuan Jing, Hao Zhou, Jingjing Zhan. (2018) Multiplex On-Bead Isotope Dimethyl Labeling Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry for Quantitative Analysis of Sulfonamides in Estuarine Ice. ANALYTICAL CHEMISTRY, 90 (20): (12172–12179). [PMID:30221932] [10.1021/acs.analchem.8b03220] |
12. Suyu Ren, Jing Tao, Feng Tan, Ying Cui, Xiaona Li, Jingwen Chen, Xin He, Yi Wang. (2018) Diffusive gradients in thin films based on MOF-derived porous carbon binding gel for in-situ measurement of antibiotics in waters. SCIENCE OF THE TOTAL ENVIRONMENT, 645 (482). [PMID:30029123] [10.1016/j.scitotenv.2018.07.013] |
13. Xiangfeng Huang, Yi Feng, Cui Hu, Xiaoyu Xiao, Daliang Yu, Xiaoming Zou. (2016) Mechanistic model for interpreting the toxic effects of sulfonamides on nitrification. JOURNAL OF HAZARDOUS MATERIALS, 305 (123). [PMID:26651069] [10.1016/j.jhazmat.2015.11.037] |
14. Lili Wang, Jing Wu, Qin Wang, Chonghui He, Lei Zhou, Jing Wang, Qiaosheng Pu. (2012) Rapid and Sensitive Determination of Sulfonamide Residues in Milk and Chicken Muscle by Microfluidic Chip Electrophoresis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 60 (7): (1613–1618). [PMID:22277081] [10.1021/jf2036577] |
1. Jiana Lin, Zenghui Xie, Yuling Hu, Gongke Li, Qisheng Zhong. (2024) Flower-like calix[6]arene-based covalent organic framework for membrane extraction of sulfonamides in animal-derived food through host-guest interaction prior to determination with ultra-high performance liquid chromatography-tandem mass spectrometry. JOURNAL OF CHROMATOGRAPHY A, 1713 (11): (464499). [PMID:37983987] [10.1016/j.chroma.2023.464499] |
2. Jing Wang, Yong Zhang, Fubin Liu, Ying Liu, Litao Wang, Guihua Gao. (2023) Preparation of a Multifunctional and Multipurpose Chitosan/Cyclodextrin/MIL-68(Al) Foam Column and Examining Its Adsorption Properties for Anionic and Cationic Dyes and Sulfonamides. ACS Omega, 8 (35): (32017–32026). [PMID:37692232] [10.1021/acsomega.3c03897] |
3. Meiling Ping, Wenchao Lv, Chen Yang, Qian Chen, Zongwen Wang, Fengfu Fu. (2023) A Paper-Based Multicolor Colorimetric Aptasensor for the Visual Determination of Multiple Sulfonamides Based on Aptamer-Functionalized Magnetic Beads and NADH–Ascorbic Acid-Mediated Gold Nanobipyramids. Chemosensors, 11 (7): (386). [PMID:] [10.3390/chemosensors11070386] |
4. Zongwen Wang, Xiating Li, Feng Zhang, Yu Gao, Jintian Cheng, FengFu Fu. (2023) Regulating the Growth Rate of Gold Nanobipyramids via a HCl-NADH-Ascorbic Acid System toward a Dual-Channel Multicolor Colorimetric Immunoassay for Simultaneously Screening and Detecting Multiple Sulfonamides. ANALYTICAL CHEMISTRY, [PMID:37382204] [10.1021/acs.analchem.3c01928] |
5. Dai Yongheng, Yuan Huayu, Li Jiang, Su Qi, Yi Qianwen, Zhang Yuntao. (2023) Direct Z-scheme P–TiO2/g-C3N4 heterojunction for the photocatalytic degradation of sulfa antibiotics. RSC Advances, 13 (9): (5957-5969). [PMID:36816086] [10.1039/D2RA07289K] |
6. Tang Jiaming, Zheng Xiaoling, Jiang Shuang, Cao Mingdong, Wang Sixian, Zhou Zhaoyang, Nie Xunqing, Fang Yu, Le Tao. (2022) Dual fluorescent aptasensor for simultanous and quantitative detection of sulfadimethoxine and oxytetracycin residues in animal-derived foods tissues based on mesoporous silica. Frontiers in Nutrition, 9 [PMID:36618689] [10.3389/fnut.2022.1077893] |
7. Ligui Wu, Mingyu Wang, Lingling Rong, Wenbiao Wang, Linwei Chen, Qiaofeng Wu, Haoyu Sun, Xiangfeng Huang, Xiaoming Zou. (2024) Structural effects of sulfonamides on the proliferation dynamics of sulfonamide resistance genes in the sequencing batch reactors and the mechanism. Journal of Environmental Sciences, 135 (161). [PMID:37778792] [10.1016/j.jes.2022.11.014] |
8. Li Gang, Wu Ming-Huo, Liu Yan, Hu Yu-Feng. (2023) Facile fluorescent probe for simultaneous fluorescence detection of fluoroquinolones and copper. CHEMICAL PAPERS, 77 (3): (1423-1432). [PMID:] [10.1007/s11696-022-02568-4] |
9. Yawen Wang, Jingwen Huang, He Guo, Chendong Puyang, Jiangang Han, Yan Li, Yunxia Ruan. (2022) Mechanism and process of sulfamethoxazole decomposition with persulfate activated by pulse dielectric barrier discharge plasma. SEPARATION AND PURIFICATION TECHNOLOGY, 287 (120540). [PMID:] [10.1016/j.seppur.2022.120540] |
10. Yang Wang, Xueyan Liu, Lei Zhang. (2020) Assembling 3D hierarchical hollow flower-like Ni@N-doped graphitic carbon for boosting simultaneously efficient removal and sensitive monitoring of multiple sulfonamides. JOURNAL OF HAZARDOUS MATERIALS, 386 (121629). [PMID:31759760] [10.1016/j.jhazmat.2019.121629] |
11. Minghuo Wu, Lin Fu, Yufeng Hu, Jingyun Su, Siyuan Jing, Hao Zhou, Jingjing Zhan. (2018) Multiplex On-Bead Isotope Dimethyl Labeling Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry for Quantitative Analysis of Sulfonamides in Estuarine Ice. ANALYTICAL CHEMISTRY, 90 (20): (12172–12179). [PMID:30221932] [10.1021/acs.analchem.8b03220] |
12. Suyu Ren, Jing Tao, Feng Tan, Ying Cui, Xiaona Li, Jingwen Chen, Xin He, Yi Wang. (2018) Diffusive gradients in thin films based on MOF-derived porous carbon binding gel for in-situ measurement of antibiotics in waters. SCIENCE OF THE TOTAL ENVIRONMENT, 645 (482). [PMID:30029123] [10.1016/j.scitotenv.2018.07.013] |
13. Xiangfeng Huang, Yi Feng, Cui Hu, Xiaoyu Xiao, Daliang Yu, Xiaoming Zou. (2016) Mechanistic model for interpreting the toxic effects of sulfonamides on nitrification. JOURNAL OF HAZARDOUS MATERIALS, 305 (123). [PMID:26651069] [10.1016/j.jhazmat.2015.11.037] |
14. Lili Wang, Jing Wu, Qin Wang, Chonghui He, Lei Zhou, Jing Wang, Qiaosheng Pu. (2012) Rapid and Sensitive Determination of Sulfonamide Residues in Milk and Chicken Muscle by Microfluidic Chip Electrophoresis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 60 (7): (1613–1618). [PMID:22277081] [10.1021/jf2036577] |