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S432841-5g

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$98.90

S432841-100g

100g

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$138.90

S432841-500g

500g

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$477.90

Basic Description

Synonyms	SULFAMIC ACID\|5329-14-6\|Amidosulfonic acid\|Sulphamic acid\|Aminosulfonic acid\|Amidosulfuric acid\|Imidosulfonic acid\|Sulfamidic acid\|Sulfaminic acid\|Jumbo\|Aminosulfuric acid\|Sulphamidic acid\|Kyselina sulfaminova\|Kyselina amidosulfonova\|Caswell No. 809\|sulfu
Specifications & Purity	high-purity, Reagent grade, ≥99%
Grade	high-purity, 试剂级
Product Description	Gene Information human ... CA1(759), CA2(760) General Description Sulfamic acid (H 2 NSO 3 H) is a strong inorganic acid. It exists in zwitterionic form and neutral forms. Zwitterionic form is more stable than neutral form. The ability of sulfamic acid/zinc powder to reduce nitrate to nitrogen gas under acidic condition has been utilized to denitrify nitrate-rich wastewater. Application Sulfamic acid (H 2 NSO 3 H) may be used in the following studies: As a catalyst in the synthesis of aryl-14 H -dibenzo[ a . j ]xanthenes. As a green catalyst for the liquid Beckmann rearrangement of ketoxime in dried acetonitrile. As a nitrogen source as well as an in situ activator of hydroxy groups in the direct iridium-catalyzed synthesis of primary allylic amines from allylic alcohols. Synthesis of polysubstituted quinolones.

Associated Targets

NR3C1 Tclin Glucocorticoid receptor 0 Activities

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CA5A Tclin Carbonic anhydrase 5A, mitochondrial 0 Activities

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TSHR Tclin Thyrotropin receptor 0 Activities

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CA5B Tclin Carbonic anhydrase 5B, mitochondrial 0 Activities

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CA6 Tclin Carbonic anhydrase 6 1 Activities

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CA13 Tclin Carbonic anhydrase 13 0 Activities

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CA1 Tclin Carbonic anhydrase 1 0 Activities

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CA2 Tclin Carbonic anhydrase 2 0 Activities

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CA4 Tclin Carbonic anhydrase 4 3 Activities

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CA12 Tclin Carbonic anhydrase 12 0 Activities

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CA14 Tclin Carbonic anhydrase 14 0 Activities

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CA9 Tclin Carbonic anhydrase 9 0 Activities

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CA7 Tclin Carbonic anhydrase 7 0 Activities

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NT5E Tchem 5'-nucleotidase 0 Activities

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NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

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CXCL8 Tchem Interleukin-8 0 Activities

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Names and Identifiers

IUPAC Name	sulfamic acid
INCHI	InChI=1S/H3NO3S/c1-5(2,3)4/h(H3,1,2,3,4)
InChi Key	IIACRCGMVDHOTQ-UHFFFAOYSA-N
Canonical SMILES	NS(=O)(=O)O
Isomeric SMILES	NS(=O)(=O)O
WGK Germany	1
PubChem CID	5987
UN Number	2967
Packing Group	III
Molecular Weight	97.09

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
D23081636	Certificate of Analysis	Mar 28, 2023	S432841
D23081640	Certificate of Analysis	Mar 28, 2023	S432841
D23081681	Certificate of Analysis	Mar 28, 2023	S432841
D23081682	Certificate of Analysis	Mar 28, 2023	S432841
D23081686	Certificate of Analysis	Mar 28, 2023	S432841

Chemical and Physical Properties

Solubility	water: 50mg/mL, clear, colorless
Melt Point(°C)	205°C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS09, GHS05
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H412:Harmful to aquatic life with long lasting effects
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	1
Class	8

References

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2. Derek J Langeslay,Szabolcs Beni,Cynthia K Larive. (2011-09-15) Detection of the 1H and 15N NMR resonances of sulfamate groups in aqueous solution: a new tool for heparin and heparan sulfate characterization.. Analytical chemistry, 83 ((20)): (8006-8010). [PMID:21913677]
3. Dengfeng Dou,Kok-Chuan Tiew,Guijia He,Sivakoteswara Rao Mandadapu,Sridhar Aravapalli,Kevin R Alliston,Yunjeong Kim,Kyeong-Ok Chang,William C Groutas. (2011-09-20) Potent inhibition of Norwalk virus by cyclic sulfamide derivatives.. Bioorganic & medicinal chemistry, 19 ((20)): (5975-5983). [PMID:21925886]
4. Marie Lopez,Hoan Vu,Conan K Wang,Maarten G Wolf,Gerrit Groenhof,Alessio Innocenti,Claudiu T Supuran,Sally-Ann Poulsen. (2011-10-01) Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors.. Journal of the American Chemical Society, 133 ((45)): (18452-18462). [PMID:21958118]
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6. Patricia Chávez,Jonathan Kirsch,Jan Streuff,Kilian Muñiz. (2012-01-31) Palladium-catalyzed intramolecular diamination of acrylic esters using sulfamates as nitrogen source.. The Journal of organic chemistry, 77 ((4)): (1922-1930). [PMID:22283802]
7. Anna Ohradanova,Daniela Vullo,Silvia Pastorekova,Jaromir Pastorek,Daniel J Jackson,Gert Wörheide,Claudiu T Supuran. (2012-01-31) Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.. Bioorganic & medicinal chemistry, 20 ((4)): (1403-1410). [PMID:22285172]
8. Daniel Can,Bernhard Spingler,Paul Schmutz,Filipa Mendes,Paula Raposinho,Célia Fernandes,Fabrizio Carta,Alessio Innocenti,Isabel Santos,Claudiu T Supuran,Roger Alberto. (2012-02-22) [(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IX.. Angewandte Chemie (International ed. in English), 51 ((14)): (3354-3357). [PMID:22344779]
9. Danielle C Lohman,Richard Wolfenden,David R Edwards. (2012-02-23) Hydrolysis of N-alkyl sulfamates and the catalytic efficiency of an S-N cleaving sulfamidase.. The Journal of organic chemistry, 77 ((6)): (2907-2910). [PMID:22352783]
10. Keisuke Takahashi,Daisuke Yamaguchi,Jun Ishihara,Susumi Hatakeyama. (2012-03-07) Total synthesis of (-)-kaitocephalin based on a Rh-catalyzed C-H amination.. Organic letters, 14 ((6)): (1644-1647). [PMID:22390213]
11. Edward J Emmett,Charlotte S Richards-Taylor,Bao Nguyen,Alfonso Garcia-Rubia,Barry R Hayter,Michael C Willis. (2012-03-13) Palladium-catalysed aminosulfonylation of aryl-, alkenyl- and heteroaryl halides: scope of the three-component synthesis of N-aminosulfonamides.. Organic & biomolecular chemistry, 10 ((20)): (4007-4014). [PMID:22407213]
12. David R Edwards,Richard Wolfenden. (2012-04-11) Proton-in-flight mechanism for the spontaneous hydrolysis of N-methyl O-phenyl sulfamate: implications for the design of steroid sulfatase inhibitors.. The Journal of organic chemistry, 77 ((9)): (4450-4453). [PMID:22486328]
13. Derek J Langeslay,Robert P Young,Szabolcs Beni,Consuelo N Beecher,Leonard J Mueller,Cynthia K Larive. (2012-05-18) Sulfamate proton solvent exchange in heparin oligosaccharides: evidence for a persistent hydrogen bond in the antithrombin-binding pentasaccharide Arixtra.. Glycobiology, 22 ((9)): (1173-1182). [PMID:22593556]
14. Christopher S Adams,Luke A Boralsky,Ilia A Guzei,Jennifer M Schomaker. (2012-06-20) Modular functionalization of allenes to aminated stereotriads.. Journal of the American Chemical Society, 134 ((26)): (10807-10810). [PMID:22708990]
15. Na Zhang,David J Hoffman,Nicholas Gutsche,Jayesh Gupta,Virgil Percec. (2012-06-21) Comparison of arylboron-based nucleophiles in Ni-catalyzed Suzuki-Miyaura cross-coupling with aryl mesylates and sulfamates.. The Journal of organic chemistry, 77 ((14)): (5956-5964). [PMID:22712768]
16. Jean-Yves Winum,Fabrizio Carta,Carol Ward,Peter Mullen,David Harrison,Simon P Langdon,Alessandro Cecchi,Andrea Scozzafava,Ian Kunkler,Claudiu T Supuran. (2012-06-23) Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.. Bioorganic & medicinal chemistry letters, 22 ((14)): (4681-4685). [PMID:22721713]
17. Weifeng Song,Lutz Ackermann. (2012-07-14) Cobalt-catalyzed direct arylation and benzylation by C-H/C-O cleavage with sulfamates, carbamates, and phosphates.. Angewandte Chemie (International ed. in English), 51 ((33)): (8251-8254). [PMID:22791393]
18. Philip T Cherian,Jiangwei Yao,Roberta Leonardi,Marcus M Maddox,Vicki A Luna,Charles O Rock,Richard E Lee. (2012-07-17) Acyl-sulfamates target the essential glycerol-phosphate acyltransferase (PlsY) in Gram-positive bacteria.. Bioorganic & medicinal chemistry, 20 ((16)): (4985-4994). [PMID:22795901]
19. Amit Saha,R B Nasir Baig,John Leazer,Rajender S Varma. (2012-07-21) A modular synthesis of dithiocarbamate pendant unnatural α-amino acids.. Chemical communications (Cambridge, England), 48 ((71)): (8889-8891). [PMID:22814637]
20. Liana Hie,Stephen D Ramgren,Tehetena Mesganaw,Neil K Garg. (2012-08-02) Nickel-catalyzed amination of aryl sulfamates and carbamates using an air-stable precatalyst.. Organic letters, 14 ((16)): (4182-4185). [PMID:22849697]
21. Tristan Reuillon,Annalisa Bertoli,Roger J Griffin,Duncan C Miller,Bernard T Golding. (2012-08-16) Efficacious N-protection of O-aryl sulfamates with 2,4-dimethoxybenzyl groups.. Organic & biomolecular chemistry, 10 ((37)): (7610-7617). [PMID:22893112]
22. M K Marchewka,M Drozd. (2012-10-20) Ethylenediammonium dication: H-bonded complexes with terephthalate, chloroacetate, phosphite, selenite and sulfamate anions. Detailed vibrational spectroscopic and theoretical studies of ethylenediammonium terephthalate.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 99 (223-233). [PMID:23078789]
23. Jean-Yves Winum,Pedro A Colinas,Claudiu T Supuran. (2012-12-04) Glycosidic carbonic anhydrase IX inhibitors: a sweet approach against cancer.. Bioorganic & medicinal chemistry, 21 ((6)): (1419-1426). [PMID:23199483]
24. Laszlo Tarko,Claudiu T Supuran. (2012-12-05) QSAR studies of sulfamate and sulfamide inhibitors targeting human carbonic anhydrase isozymes I, II, IX and XII.. Bioorganic & medicinal chemistry, 21 ((6)): (1404-1409). [PMID:23206986]
25. Toolika Agrawal,Silas P Cook. (2012-12-19) Iron-catalyzed cross-coupling reactions of alkyl Grignards with aryl sulfamates and tosylates.. Organic letters, 15 ((1)): (96-99). [PMID:23244161]
26. Hao Yu,Lei Zhang,Zhilin Yang,Zhen Li,Yan Zhao,Yumei Xiao,Hongchao Guo. (2013-07-31) Phosphine-catalyzed [3 + 2] cycloaddition of sulfamate-derived cyclic imines with allenoate: synthesis of sulfamate-fused dihydropyrroles.. The Journal of organic chemistry, 78 ((17)): (8427-8436). [PMID:23895382]
27. Fabian Soltermann,Tobias Widler,Silvio Canonica,Urs von Gunten. (2014-04-29) Comparison of a novel extraction-based colorimetric (ABTS) method with membrane introduction mass spectrometry (MIMS): trichloramine dynamics in pool water.. Water research, 58 (258-268). [PMID:24769062]
28. Xolelwa Lamani,Simeon Horst,Thomas Zimmermann,Torsten C Schmidt. (2014-08-22) Determination of aromatic amines in human urine using comprehensive multi-dimensional gas chromatography mass spectrometry (GCxGC-qMS).. Analytical and bioanalytical chemistry, 407 ((1)): (241-252). [PMID:25142049]
29. Mohammad Rashid Khan,Haseeb Ahsan,Shabeena Siddiqui,Waseem A Siddiqui. (2014-09-19) Tocotrienols have a nephroprotective action against lipid-induced chronic renal dysfunction in rats.. Renal failure, 37 ((1)): (136-143). [PMID:25231142]
30. Juho Antti Sirviö,Henrikki Liimatainen,Miikka Visanko,Jouko Niinimäki. (2014-09-30) Optimization of dicarboxylic acid cellulose synthesis: reaction stoichiometry and role of hypochlorite scavengers.. Carbohydrate polymers, 114 (73-77). [PMID:25263866]
31. Ning Dai,Amisha D Shah,Lanhua Hu,Michael J Plewa,Bruce McKague,William A Mitch. (2012-07-27) Measurement of nitrosamine and nitramine formation from NOx reactions with amines during amine-based carbon dioxide capture for postcombustion carbon sequestration.. Environmental science & technology, 46 ((17)): (9793-9801). [PMID:22831707]
32. Sandro Castronovo,Arne Wick,Marco Scheurer,Karsten Nödler,Manoj Schulz,Thomas A Ternes. (2017-01-08) Biodegradation of the artificial sweetener acesulfame in biological wastewater treatment and sandfilters.. Water research, 110 (342-353). [PMID:28063296]

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Sulfamic acid - Reagent Plus, ≥99%, high purity , CAS No.5329-14-6