Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P160775-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $9.90 | |
P160775-5g | 5g | In stock | $22.90 | |
P160775-25g | 25g | In stock | $63.90 | |
P160775-100g | 100g | In stock | $229.90 |
D 2 -like dopamine receptor antagonist
Synonyms | sulpiride | 15676-16-1 | Sulpyrid | Dolmatil | Sulpirid | Aiglonyl | (+/-)-Sulpiride | Dogmatil | Dobren | Dogmatyl | Guastil | Miradol | Mirbanil | Misulvan | Omperan | Splotin | Sursumid | Abilit | Meresa | Coolspan | Sernevin | Neogama | (RS)-(+/-)-sulpiride | Pyrkappl | Eglonyl | Calmoflorine | Champio |
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Specifications & Purity | Moligand™, ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | (RS)-(±)-Sulpiride is a selective postsynaptic D2DR inhibitor.D 2 -like dopamine receptor antagonist. Shows antipsychotic activity. Active enantiomer ( S )-sulpiride also available. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | ANTAGONIST, INHIBITOR |
Mechanism of action | Dopamine D2 receptor antagonist |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | A D2DR inhibitor |
ALogP | 0.6 |
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IUPAC Name | N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide |
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INCHI | InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) |
InChi Key | BGRJTUBHPOOWDU-UHFFFAOYSA-N |
Canonical SMILES | CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC |
Isomeric SMILES | CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC |
WGK Germany | 2 |
RTECS | BZ3400000 |
PubChem CID | 5355 |
Molecular Weight | 341.43 |
Reaxy-Rn | 494008 |
Wikipedia | Sulpiride |
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DrugBank Ligand | DB00391 |
CAS Registry No. | 15676-16-1 |
ChEBI | CHEBI:32168 |
ChEMBL Ligand | CHEMBL26 |
PubChem CID | 5355 |
PEP | sulpiride |
DrugCentral Ligand | 2537 |
GPCRdb Ligand | sulpiride |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
B2318604 | Certificate of Analysis | Feb 02, 2023 | P160775 |
B2318605 | Certificate of Analysis | Feb 02, 2023 | P160775 |
B2318606 | Certificate of Analysis | Feb 02, 2023 | P160775 |
B2318607 | Certificate of Analysis | Feb 02, 2023 | P160775 |
B2320077 | Certificate of Analysis | Feb 02, 2023 | P160775 |
B2320566 | Certificate of Analysis | Feb 02, 2023 | P160775 |
F2413082 | Certificate of Analysis | Feb 02, 2023 | P160775 |
G2401063 | Certificate of Analysis | Feb 02, 2023 | P160775 |
I2226228 | Certificate of Analysis | Sep 28, 2022 | P160775 |
G2211010 | Certificate of Analysis | Jul 14, 2022 | P160775 |
C2225016 | Certificate of Analysis | Mar 29, 2022 | P160775 |
Refractive Index | 1.55 |
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Melt Point(°C) | 178-180°C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H302+H312+H332:Harmful if swallowed, in contact with skin or if inhaled H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. |
WGK Germany | 2 |
RTECS | BZ3400000 |
Reaxy-Rn | 494008 |
Merck Index | 8989 |
1. Huanhuan Yang, Cong Liu, Chuanhong Zhu, Yan Zheng, Juan Li, Qianyun Zhu, Hao Wang, Xiangming Fang, Quan Liu, Man Liang, Zilong Liu. (2023) Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 234 (115557). [PMID:37406464] |
1. Blythe SN et al.. (2009) Cellular mechanisms underlying burst firing in substantia nigra dopamine neurons.. J Neurosci, 29 (49): (15531-41). [PMID:20007477] |
2. Huanhuan Yang, Cong Liu, Chuanhong Zhu, Yan Zheng, Juan Li, Qianyun Zhu, Hao Wang, Xiangming Fang, Quan Liu, Man Liang, Zilong Liu. (2023) Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 234 (115557). [PMID:37406464] |