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(±)-Sulpiride - >98.0%(HPLC), high purity , Dopamine D2 receptor antagonist, CAS No.15676-16-1, Dopamine D2 receptor antagonist
D 2 -like dopamine receptor antagonist
Basic Description Synonyms sulpiride|15676-16-1|Sulpyrid|Dolmatil|Sulpirid|Aiglonyl|(+/-)-Sulpiride|Dogmatil|Dobren|Dogmatyl|Guastil|Miradol|Mirbanil|Misulvan|Omperan|Splotin|Sursumid|Abilit|Meresa|Coolspan|Sernevin|Neogama|(RS)-(+/-)-sulpiride|Pyrkappl|Eglonyl|Calmoflorine|Champio Specifications & Purity >98.0%(HPLC) Storage Temp Store at 2-8°C Shipped In Wet ice Action Type ANTAGONIST, INHIBITOR Mechanism of action Dopamine D2 receptor antagonist Product Description A D2DR inhibitor
Names and Identifiers IUPAC Name N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide INCHI InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) InChi Key BGRJTUBHPOOWDU-UHFFFAOYSA-N Canonical SMILES CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC Isomeric SMILES CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC WGK Germany 2 RTECS BZ3400000 PubChem CID 5355 Molecular Weight 341.43 Reaxy-Rn 494008
Chemical and Physical Properties Refractive Index 1.55 Melt Point(°C) 178-180°C
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Warning Hazard Statements H302: Harmful if swallowed
H312: Harmful in contact with skin
H332: Harmful if inhaled
H302+H312+H332: Harmful if swallowed, in contact with skin or if inhaled
H361: Suspected of damaging fertility or the unborn child
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P270: Do not eat, drink or smoke when using this product.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P362+P364: Take off contaminated clothing and wash it before reuse.
P330: Rinse mouth.
P203: Obtain, read and follow all safety instructions before use.
P301+P317: IF SWALLOWED: Get medical help.
P318: if exposed or concerned, get medical advice.
P317: Get emergency medical help.
WGK Germany 2 RTECS BZ3400000 Reaxy-Rn 494008 Merck Index 8989
References 1. Blythe SN et al.. (2009) Cellular mechanisms underlying burst firing in substantia nigra dopamine neurons.. J Neurosci, 29 (49): (15531-41). [PMID:20007477 ]
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