Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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S421876-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
D 2 -like dopamine receptor antagonist
Synonyms | sulpiride | 15676-16-1 | Sulpyrid | Dolmatil | Sulpirid | Aiglonyl | (+/-)-Sulpiride | Dogmatil | Dobren | Dogmatyl | Guastil | Miradol | Mirbanil | Misulvan | Omperan | Splotin | Sursumid | Abilit | Meresa | Coolspan | Sernevin | Neogama | (RS)-(+/-)-sulpiride | Pyrkappl | Eglonyl | Calmoflorine | Champio |
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Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | (RS)-(±)-Sulpiride is a selective postsynaptic D2DR inhibitor.D 2 -like dopamine receptor antagonist. Shows antipsychotic activity. Active enantiomer ( S )-sulpiride also available. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | A D2DR inhibitor |
ALogP | 0.6 |
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IUPAC Name | N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide |
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INCHI | InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) |
InChi Key | BGRJTUBHPOOWDU-UHFFFAOYSA-N |
Canonical SMILES | CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC |
Isomeric SMILES | CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC |
WGK Germany | 2 |
RTECS | BZ3400000 |
PubChem CID | 5355 |
Molecular Weight | 341.43 |
Reaxy-Rn | 494008 |
Enter Lot Number to search for COA:
Refractive Index | 1.55 |
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Melt Point(°C) | 178-180°C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H302+H312+H332:Harmful if swallowed, in contact with skin or if inhaled H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. |
WGK Germany | 2 |
RTECS | BZ3400000 |
Reaxy-Rn | 494008 |
Merck Index | 8989 |
1. Huanhuan Yang, Cong Liu, Chuanhong Zhu, Yan Zheng, Juan Li, Qianyun Zhu, Hao Wang, Xiangming Fang, Quan Liu, Man Liang, Zilong Liu. (2023) Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 234 (115557). [PMID:37406464] |
2. Shaohua She, Yifan Wang, Rong Chen, Futao Yi, Chuanzhi Sun, Jiayue Hu, Zhi Li, Gang Lu, Mingshan Zhu. (2021) Ultrathin S-doped graphitic carbon nitride nanosheets for enhanced sulpiride degradation via visible-light-assisted peroxydisulfate activation: Performance and mechanism. CHEMOSPHERE, 266 (128929). [PMID:33199111] |
3. Nan Zhang, Mu Luo, Lei He, Lei Yao. (2020) Chemical Composition of Essential Oil from Flower of ‘Shanzhizi’ (Gardenia jasminoides Ellis) and Involvement of Serotonergic System in Its Anxiolytic Effect. MOLECULES, 25 (20): (4702). [PMID:33066512] |
4. Kai Zhang, Jing Lu, Lei Yao. (2020) Involvement of the dopamine D1 receptor system in the anxiolytic effect of cedrol in the elevated plus maze and light–dark box tests. JOURNAL OF PHARMACOLOGICAL SCIENCES, 142 (26). [PMID:31786058] |
5. Chengcan Lu, Kejia Fu, Kangna Cao, Jiali Wei, Jing Zhou, Di Zhao, Ning Li, Yang Lu, Xijing Chen, Yongjie Zhang. (2020) Permeability and transport mechanism of trihexyphenidyl hydrochloride in Caco-2 cell monolayer model with a validated UPLC-MS/MS method. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 178 (112924). [PMID:31672580] |
1. Huanhuan Yang, Cong Liu, Chuanhong Zhu, Yan Zheng, Juan Li, Qianyun Zhu, Hao Wang, Xiangming Fang, Quan Liu, Man Liang, Zilong Liu. (2023) Determination of ten antipsychotics in blood, hair and nails: Validation of a LC–MS/MS method and forensic application of keratinized matrix analysis. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 234 (115557). [PMID:37406464] |
2. Shaohua She, Yifan Wang, Rong Chen, Futao Yi, Chuanzhi Sun, Jiayue Hu, Zhi Li, Gang Lu, Mingshan Zhu. (2021) Ultrathin S-doped graphitic carbon nitride nanosheets for enhanced sulpiride degradation via visible-light-assisted peroxydisulfate activation: Performance and mechanism. CHEMOSPHERE, 266 (128929). [PMID:33199111] |
3. Nan Zhang, Mu Luo, Lei He, Lei Yao. (2020) Chemical Composition of Essential Oil from Flower of ‘Shanzhizi’ (Gardenia jasminoides Ellis) and Involvement of Serotonergic System in Its Anxiolytic Effect. MOLECULES, 25 (20): (4702). [PMID:33066512] |
4. Kai Zhang, Jing Lu, Lei Yao. (2020) Involvement of the dopamine D1 receptor system in the anxiolytic effect of cedrol in the elevated plus maze and light–dark box tests. JOURNAL OF PHARMACOLOGICAL SCIENCES, 142 (26). [PMID:31786058] |
5. Chengcan Lu, Kejia Fu, Kangna Cao, Jiali Wei, Jing Zhou, Di Zhao, Ning Li, Yang Lu, Xijing Chen, Yongjie Zhang. (2020) Permeability and transport mechanism of trihexyphenidyl hydrochloride in Caco-2 cell monolayer model with a validated UPLC-MS/MS method. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 178 (112924). [PMID:31672580] |