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Sulprostone - ≥98%, high purity , CAS No.60325-46-4, Agonist of EP 1 receptor;Agonist of EP 3 receptor;Agonist of FP receptor

  • Moligand™
  • ≥98%
Item Number
S274841
Grouped product items
SKUSizeAvailabilityPrice Qty
S274841-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$171.90
S274841-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$773.90

Selective EP 1 / EP 3 receptor agonist. PGE 2 analog.

Basic Description

SynonymsSulprostone|60325-46-4|Nalador|CP-34089|ZK-57671|CP-34,089|ZK 57 671|501Q5EQ1GM|Sulprostone in 5mg/ml Methyl Acetate|Sulprostonum|(Z)-7-((1R,2R,3R)-3-Hydroxy-2-((E)-(3R)-(3-hydroxy-4-phenoxy-1-butenyl))-5-oxocyclopentyl)-N-(methylsulfonyl)-5-heptenamide|
Specifications & Purity≥98%
Storage TempStore at -20°C,Desiccated
Shipped InDry ice
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of EP 1 receptor;Agonist of EP 3 receptor;Agonist of FP receptor
Product Description

Store at -20°C (desiccating conditions).


application:

Human chondrocytes3 and mouse adrenal chromaffin cells4 were treated with sulprostone to study the biological effects of PGE2.

Associated Targets

PTGER1 Tclin Prostaglandin E2 receptor EP1 subtype 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGFR Tclin Prostaglandin F2-alpha receptor 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PTGER3 Tclin Prostaglandin E2 receptor EP3 subtype 5 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]-N-methylsulfonylhept-5-enamide
INCHI InChI=1S/C23H31NO7S/c1-32(29,30)24-23(28)12-8-3-2-7-11-19-20(22(27)15-21(19)26)14-13-17(25)16-31-18-9-5-4-6-10-18/h2,4-7,9-10,13-14,17,19-20,22,25,27H,3,8,11-12,15-16H2,1H3,(H,24,28)/b7-2-,14-13+/t17-,19-,20-,22-/m1/s1
InChi Key UQZVCDCIMBLVNR-TWYODKAFSA-N
Canonical SMILES CS(=O)(=O)NC(=O)CCCC=CCC1C(C(CC1=O)O)C=CC(COC2=CC=CC=C2)O
Isomeric SMILES CS(=O)(=O)NC(=O)CCC/C=C\C[C@@H]1[C@H]([C@@H](CC1=O)O)/C=C/[C@H](COC2=CC=CC=C2)O
PubChem CID 5312153
Molecular Weight 465.65

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySupplied in methyl acetate (10 mg/ml)

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H311:Toxic in contact with skin

H331:Toxic if inhaled

H300:Fatal if swallowed

H360:May damage fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P361+P364:Take off immediately all contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

Related Documents

Solution Calculators