Suramin hexasodium salt - ≥98%, high purity , Acidic fibroblast growth factor inhibitor, CAS No.129-46-4, Acidic fibroblast growth factor inhibitor

Item Number

S131869

• Synonyms: SURAMIN SODIUM [WHO-DD] | EINECS 204-949-3 | Nagananinum | Bayer 205 (TN) | Suramine sodique | AS-81747 | Suramine sodique [INN-French] | BAY-205 | Suramin. Hexasodium Salt | NCGC00094436-02 | Suramin (sodium salt) | M02480 | hexasodium;8-[[4-methyl-3-[[3
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: Suramin is a polysulfonated naphthylurea anticancer agent that inhibits tumor cell proliferation. It inhibits the activity of topoisomerase II by blocking the binding of the enzyme to DNA. It′s antiangiogenic activity may be related to its ability to bind
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Action Type: INHIBITOR
• Mechanism of action: Acidic fibroblast growth factor inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Suramin sodium salt has been used:
as a potent blocker of rat P2Y2 purinergic receptor
to study its effects on short circuit current (Isc) across strial marginal cells
to show its effects on initial burst of glial activity
to assess its neuroprotective potential in rats
as a purinoceptor inhibitor, to explore the mechanism of action of extracellular adenosine triphosphate (eATP)