SW 033291 - ≥98%(HPLC), high purity , CAS No.459147-39-8

  • ≥98%(HPLC)
Item Number
S288218
Grouped product items
SKUSizeAvailabilityPrice Qty
S288218-5mg
5mg
In stock
$98.90
S288218-10mg
10mg
In stock
$147.90
S288218-25mg
25mg
In stock
$333.90
S288218-50mg
50mg
In stock
$444.90
S288218-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$642.90
S288218-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,446.90

Discover SW 033291 by Aladdin Scientific in ≥98%(HPLC) for only $98.90. Available - in Ligands at Aladdin Scientific. High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation. Tags: .

Basic Description

SynonymsNSC787269 | s7900 | SB19146 | SCHEMBL15525569 | 2-butylsulfinyl-4-phenyl-6-thiophen-2-ylthieno[2,3-b]pyridin-3-amine | US9789116, SW033291 | AC-32909 | SW033291, >=98% (HPLC) | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine | Z22138
Specifications & Purity≥98%(HPLC)
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Description
SW033291 is a selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) with IC50 and Kiapp of 1.5 nM and 0.1 nM, respectively.

Associated Targets(Human)

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Liver (3974 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasma (328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 2-butylsulfinyl-4-phenyl-6-thiophen-2-ylthieno[2,3-b]pyridin-3-amine
INCHI InChI=1S/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3
InChi Key LCYAYKSMOVLVRL-UHFFFAOYSA-N
Canonical SMILES CCCCS(=O)C1=C(C2=C(S1)N=C(C=C2C3=CC=CC=C3)C4=CC=CS4)N
Isomeric SMILES CCCCS(=O)C1=C(C2=C(S1)N=C(C=C2C3=CC=CC=C3)C4=CC=CS4)N
PubChem CID 3337839
Molecular Weight 412.59

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
F2204862Certificate of AnalysisFeb 28, 2022 S288218
F2204863Certificate of AnalysisFeb 28, 2022 S288218
F2204864Certificate of AnalysisFeb 28, 2022 S288218
F2204865Certificate of AnalysisFeb 28, 2022 S288218
F2204866Certificate of AnalysisFeb 28, 2022 S288218
F2204960Certificate of AnalysisFeb 28, 2022 S288218

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 41.26, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 8.25, Max Conc. mM: 20
Melt Point(°C)>99°C (Dec)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

RIDADR NONHforallmodesoftransport

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