SW155246 - 98%, high purity , CAS No.420092-79-1

  • ≥98%
Item Number
S412943
Grouped product items
SKUSizeAvailabilityPrice Qty
S412943-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
S412943-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$110.90
S412943-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$221.90
S412943-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$354.90
S412943-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$567.90
S412943-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$993.90

Basic Description

SynonymsSW155246 | 420092-79-1 | 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide | CHEMBL3414633 | 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide | 1-yl)-3-nitrobenzenesulfonamide | SCHEMBL17927205 | 4-chloro-N-(4-hydroxynaphthalen- | EX-A4688 | V
Specifications & Purity≥98%
Biochemical and Physiological MechanismsSW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor with IC50 of 1.2 μM. SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

SW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor with IC50 of 1.2 μM. SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.

Associated Targets(Human)

DNMT1 Tclin DNA (cytosine-5)-methyltransferase 1 (978 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DNMT3A Tclin DNA (cytosine-5)-methyltransferase 3A (310 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 4-chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide
INCHI InChI=1S/C16H11ClN2O5S/c17-13-6-5-10(9-15(13)19(21)22)25(23,24)18-14-7-8-16(20)12-4-2-1-3-11(12)14/h1-9,18,20H
InChi Key JDYDEJYIVZNWQU-UHFFFAOYSA-N
Canonical SMILES C1=CC=C2C(=C1)C(=CC=C2O)NS(=O)(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]
Isomeric SMILES C1=CC=C2C(=C1)C(=CC=C2O)NS(=O)(=O)C3=CC(=C(C=C3)Cl)[N+](=O)[O-]
PubChem CID 3718032
Molecular Weight 378.79

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
B2421343Certificate of AnalysisJan 11, 2024 S412943
B2421365Certificate of AnalysisJan 11, 2024 S412943
B2421367Certificate of AnalysisJan 11, 2024 S412943
B2421368Certificate of AnalysisJan 11, 2024 S412943
B2421369Certificate of AnalysisJan 11, 2024 S412943
B2421370Certificate of AnalysisJan 11, 2024 S412943
B2421371Certificate of AnalysisJan 11, 2024 S412943
B2421372Certificate of AnalysisJan 11, 2024 S412943
B2421373Certificate of AnalysisJan 11, 2024 S412943
B2421374Certificate of AnalysisJan 11, 2024 S412943
B2421375Certificate of AnalysisJan 11, 2024 S412943
B2421376Certificate of AnalysisJan 11, 2024 S412943

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Chemical and Physical Properties

SolubilityDMSO: 50 mg/mL (132 mM)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

RIDADR NONHforallmodesoftransport

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