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Syk Inhibitor(Isomer mixture) - ≥98.0%(mixture of isomers), high purity , CAS No.622387-85-3, Inhibitor of spleen associated tyrosine kinase

  • Moligand™
  • ≥98%
  • mixture of isomers
Item Number
S274810
Grouped product items
SKUSizeAvailabilityPrice Qty
S274810-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
S274810-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$162.90
S274810-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$424.90
S274810-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$849.90
S274810-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,529.90

Potent, selective inhibitor of B cell signaling and function

Basic Description

Synonyms622387-85-3|3-[(1-methyl-3-indolyl)methylidene]-2-oxo-1H-indole-5-sulfonamide|3-[(1-methylindol-3-yl)methylidene]-2-oxo-1H-indole-5-sulfonamide|OXSI 2|N-Boc-4-phenylnipecoticacid|DTXSID30648015|Q27164252|(Z)-3-((1-methyl-1H-indol-3-yl)methylene)-2-oxoindo
Specifications & Purity≥98.0%(mixture of isomers)
Storage TempProtected from light,Store at -20°C,Argon charged,Desiccated
Shipped InDry ice
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of spleen associated tyrosine kinase
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets

SYK Tclin Tyrosine-protein kinase SYK 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 3-[(1-methylindol-3-yl)methylidene]-2-oxo-1H-indole-5-sulfonamide
INCHI InChI=1S/C18H15N3O3S/c1-21-10-11(13-4-2-3-5-17(13)21)8-15-14-9-12(25(19,23)24)6-7-16(14)20-18(15)22/h2-10H,1H3,(H,20,22)(H2,19,23,24)
InChi Key MLKHXLFEYOOYEY-UHFFFAOYSA-N
Canonical SMILES CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC(=C4)S(=O)(=O)N)NC3=O
Isomeric SMILES CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC(=C4)S(=O)(=O)N)NC3=O
PubChem CID 24906266
Molecular Weight 353.39

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO to 10 mM
Sensitivitylight sensitive

Related Documents

References

1. Lai JY, Cox PJ, Patel R, Sadiq S, Aldous DJ, Thurairatnam S, Smith K, Wheeler D, Jagpal S, Parveen S et al..  (2003)  Potent small molecule inhibitors of spleen tyrosine kinase (Syk)..  Bioorg Med Chem Lett,  13  (18): (3111-4).  [PMID:12941345]

Solution Calculators