Determine the necessary mass, volume, or concentration for preparing a solution.
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Synonyms | SYRINGIC ACID | 530-57-4 | 4-Hydroxy-3,5-dimethoxybenzoic acid | 3,5-Dimethoxy-4-hydroxybenzoic acid | Cedar acid | Gallic acid 3,5-dimethyl ether | Benzoic acid, 4-hydroxy-3,5-dimethoxy- | NSC 2129 | 3,5-Dimethoxy-4-hydroxybenzyl acid | EINECS 208-486-8 | BRN 2115262 | UNII-E |
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Specifications & Purity | 10mM in DMSO |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
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IUPAC Name | 4-hydroxy-3,5-dimethoxybenzoic acid |
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INCHI | InChI=1S/C9H10O5/c1-13-6-3-5(9(11)12)4-7(14-2)8(6)10/h3-4,10H,1-2H3,(H,11,12) |
InChi Key | JMSVCTWVEWCHDZ-UHFFFAOYSA-N |
Canonical SMILES | COC1=CC(=CC(=C1O)OC)C(=O)O |
Isomeric SMILES | COC1=CC(=CC(=C1O)OC)C(=O)O |
WGK Germany | 3 |
RTECS | DH2090000 |
PubChem CID | 10742 |
Molecular Weight | 198.17 |
Beilstein | 2115262 |
Reaxy-Rn | 2115262 |
Enter Lot Number to search for COA:
Sensitivity | Moisture sensitive. |
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Boil Point(°C) | 192-193°/14mm |
Melt Point(°C) | 206-212°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | DH2090000 |
Reaxy-Rn | 2115262 |
1. Dali Fu, Haodong Wang, Tan Wang, Chunming Xu, Yehua Han. (2023) Structural insights into variation of intramolecular acid site using phase transition experiments and computation. AICHE JOURNAL, 70 (4): (e18342). [PMID:] |
2. Guanghe Zhao, Ruifen Zhang, Lihong Dong, Mei Deng, Yanxia Chen, Mingwei Zhang. (2023) The effects of different enzymes on the liberation of bound phenolics from rice bran dietary fibre and their antioxidant activities. Food Bioscience, 56 (103449). [PMID:] |
3. Daihong Gao, Denghao Ouyang, Xuebing Zhao. (2024) Controllable oxidative depolymerization of lignin to produce aromatic aldehydes and generate electricity under mild conditions with direct biomass fuel cells as flexible reactors. CHEMICAL ENGINEERING JOURNAL, 479 (147874). [PMID:] |
4. Liu Xinru, Ma Qianwei, Sun Yongjun, Ju Wenming, Kumrungsee Thanutchaporn, Zhou Zhongkai, Wang Lijuan, Cao Ruge. (2023) Effects of Processings and Complexation on Solubility, Antioxidant and Antibacterial Properties of Buckwheat Polyphenols. Food and Bioprocess Technology, (8): (1-13). [PMID:18063578] |
5. Yan Shi, Wei Xu, Dawei Ni, Wenli Zhang, Cuie Guang, Wanmeng Mu. (2024) Identification and application of a novel deoxynivalenol-degrading enzyme from Youhaiella tibetensis. FOOD CHEMISTRY, 435 (137609). [PMID:37783127] |
6. Chen Zhong, Hongbin Cao, Qingguo Huang, Yongbing Xie, He Zhao. (2023) Degradation of Sulfamethoxazole by Manganese(IV) Oxide in the Presence of Humic Acid: Role of Stabilized Semiquinone Radicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57 (36): (13625–13634). [PMID:37650769] |
7. Ping Fu, Di Zhou, Wan-Long Li, Wan-Ting Lin, Xiao-Jun Huang, Zhi-Kang Xu, Ling-Shu Wan. (2023) Laccase-triggered one-step fabrication of positively charged phenolic acid-amine networks for nanofiltration. DESALINATION, 566 (116946). [PMID:] |
8. Ping Fu, Chang Liu, Wan-Long Li, Di Zhou, Xiao-Jun Huang, Zhi-Kang Xu, Ling-Shu Wan. (2023) Metal–Phenolic Acid Networks Enable Nanofiltration Membranes for Rapid and Precise Molecular Separation. ACS Applied Nano Materials, 6 (12): (10791–10803). [PMID:] |
9. Wenyuan Zhang, Songjuan Zhuang, Hui Guan, Feng Li, Hui Zou, Dapeng Li. (2023) New insights into the anti-apoptotic mechanism of natural polyphenols in complex with Bax protein. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, [PMID:37184126] |
10. Wenwen Guan, Duqin Zhang, Bin Tan. (2023) Effect of Layered Debranning Processing on the Proximate Composition, Polyphenol Content, and Antioxidant Activity of Whole Grain Wheat. JOURNAL OF FOOD PROCESSING AND PRESERVATION, 2023 (1083867). [PMID:] |
11. Mingyan Liu, Xingzi Yao, Gaowei Zhang, Shengxiang Yi, Xueyong Huang, Fangjian Ning, Liping Luo. (2023) Physicochemical properties, chemical constituents, and antioxidant activity of Eurya honey. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 58 (6): (3458-3468). [PMID:] |
12. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] |
13. Lixia Yang, Zhendong Lu, Jian Lu, Dianhui Wu. (2022) Evaluation of the antioxidant characteristics of craft beer with green tea. JOURNAL OF FOOD SCIENCE, 88 (2): (625-637). [PMID:36576119] |
14. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2023) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). [PMID:36484340] |
15. Zhigui He, Yanfeng Wang, Yan Yan, Shaowei Qin, Huan He, Renjun Mao, Zongsuo Liang. (2022) Dynamic analysis of physiological indices and transcriptome profiling revealing the mechanisms of the allelopathic effects of phenolic acids on Pinellia ternata.. Frontiers in Plant Science, 13 (1039507-1039507). [PMID:36340387] |
16. Yaping Li, Ningning Sun, Songxin Ma, Xin Zhang, Yingfeng Wang, Xingru Li. (2022) Magnetic thermo-responsive branched polymer for fast extraction and enrichment of phenolic acids in olive oil with tunable and enhanced performance. ANALYTICA CHIMICA ACTA, 1229 (340359). [PMID:36156232] |
17. Yang Guangxu, Gong Zhenggang, Luo Xiaolin, Shuai Li. (2022) Revisiting alkaline cupric oxide oxidation method for lignin structural analysis. Frontiers in Bioengineering and Biotechnology, 10 [PMID:36159682] |
18. Duqin Zhang, Yanjun Ye, Bin Tan. (2022) Comparative study of solid-state fermentation with different microbial strains on the bioactive compounds and microstructure of brown rice. FOOD CHEMISTRY, 397 (133735). [PMID:35914455] |
19. Kangling Yin, Li Chen, Feng Liu, Taotao Fan, Yuehang Wu, Shuai Li, Zongcheng Yan. (2022) Liquid–Liquid Equilibrium Data for Novel Aqueous Two-Phase Systems Composed of Betaine-Xylitol Deep Eutectic Solvent + Alcohol (1-Propanol/2-Propanol/tert-Butanol) + Water. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 67 (9): (2475–2485). [PMID:] |
20. Lifen Meng, Zhi Xia, Jingsong Lv, Gaofu Liu, Ye Tan, Qianzhu Li. (2022) Extraction and GC-MS analysis of phenolic acids in rhizosphere soil of Pinellia ternate. Journal of Radiation Research and Applied Sciences, 15 (40). [PMID:] |
21. Guanghe Zhao, Ruifen Zhang, Lihong Dong, Lei Liu, Fei Huang, Xuchao Jia, Mei Deng, Jianwei Chi, Yongxuan Ma, Yanxia Chen, Qin Ma, Mingwei Zhang. (2022) Bound phenolics in rice bran dietary fibre released by different chemical hydrolysis methods: content, composition and antioxidant activities. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 57 (9): (5909-5916). [PMID:] |
22. Ya zhu Wang, Jin Zheng, Muhammad Nawaz, Fan Yang, Jiajun Hu, Min-Tian Gao. (2022) Oligosaccharide-phenolic compound conjugates in soluble polysaccharides from rice straw alleviate ethanol fermentation stresses in Saccharomyces cerevisiae. INDUSTRIAL CROPS AND PRODUCTS, 181 (114782). [PMID:] |
23. Zhan-Qian Ma, Cui-Ping Yi, Na-Na Wu, Bin Tan. (2022) Steaming retains more phenolics, dietary fiber, and antioxidant activities than cooking for rice with different milling processes. CEREAL CHEMISTRY, 99 (3): (664-679). [PMID:] |
24. Shuai Zhang, Qin Ma, Lihong Dong, Xuchao Jia, Lei Liu, Fei Huang, Guang Liu, Zhida Sun, Jianwei Chi, Mingwei Zhang, Ruifen Zhang. (2022) Phenolic profiles and bioactivities of different milling fractions of rice bran from black rice. FOOD CHEMISTRY, 378 (132035). [PMID:35042109] |
25. Kangling Yin, Li Chen, Feng Liu, Taotao Fan, Zongcheng Yan. (2022) Pseudoternary Systems of Deep Eutectic Solvents + tert-Butanol + Water at T = 288.15 K, 298.15 K, and 308.15 K: Liquid–Liquid Equilibrium and Ability for Syringic Acid/Eugenol Separation. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 67 (1): (200–211). [PMID:] |
26. Wenfei Tian, Jingyang Tong, Xiaoyue Zhu, Philipp Fritschi Martin, Yonghui Li, Zhonghu He, Yan Zhang. (2021) Effects of Different Pilot-Scale Milling Methods on Bioactive Components and End-Use Properties of Whole Wheat Flour. Foods, 10 (11): (2857). [PMID:34829138] |
1. Dali Fu, Haodong Wang, Tan Wang, Chunming Xu, Yehua Han. (2023) Structural insights into variation of intramolecular acid site using phase transition experiments and computation. AICHE JOURNAL, 70 (4): (e18342). [PMID:] |
2. Guanghe Zhao, Ruifen Zhang, Lihong Dong, Mei Deng, Yanxia Chen, Mingwei Zhang. (2023) The effects of different enzymes on the liberation of bound phenolics from rice bran dietary fibre and their antioxidant activities. Food Bioscience, 56 (103449). [PMID:] |
3. Daihong Gao, Denghao Ouyang, Xuebing Zhao. (2024) Controllable oxidative depolymerization of lignin to produce aromatic aldehydes and generate electricity under mild conditions with direct biomass fuel cells as flexible reactors. CHEMICAL ENGINEERING JOURNAL, 479 (147874). [PMID:] |
4. Liu Xinru, Ma Qianwei, Sun Yongjun, Ju Wenming, Kumrungsee Thanutchaporn, Zhou Zhongkai, Wang Lijuan, Cao Ruge. (2023) Effects of Processings and Complexation on Solubility, Antioxidant and Antibacterial Properties of Buckwheat Polyphenols. Food and Bioprocess Technology, (8): (1-13). [PMID:18063578] |
5. Yan Shi, Wei Xu, Dawei Ni, Wenli Zhang, Cuie Guang, Wanmeng Mu. (2024) Identification and application of a novel deoxynivalenol-degrading enzyme from Youhaiella tibetensis. FOOD CHEMISTRY, 435 (137609). [PMID:37783127] |
6. Chen Zhong, Hongbin Cao, Qingguo Huang, Yongbing Xie, He Zhao. (2023) Degradation of Sulfamethoxazole by Manganese(IV) Oxide in the Presence of Humic Acid: Role of Stabilized Semiquinone Radicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 57 (36): (13625–13634). [PMID:37650769] |
7. Ping Fu, Di Zhou, Wan-Long Li, Wan-Ting Lin, Xiao-Jun Huang, Zhi-Kang Xu, Ling-Shu Wan. (2023) Laccase-triggered one-step fabrication of positively charged phenolic acid-amine networks for nanofiltration. DESALINATION, 566 (116946). [PMID:] |
8. Ping Fu, Chang Liu, Wan-Long Li, Di Zhou, Xiao-Jun Huang, Zhi-Kang Xu, Ling-Shu Wan. (2023) Metal–Phenolic Acid Networks Enable Nanofiltration Membranes for Rapid and Precise Molecular Separation. ACS Applied Nano Materials, 6 (12): (10791–10803). [PMID:] |
9. Wenyuan Zhang, Songjuan Zhuang, Hui Guan, Feng Li, Hui Zou, Dapeng Li. (2023) New insights into the anti-apoptotic mechanism of natural polyphenols in complex with Bax protein. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, [PMID:37184126] |
10. Wenwen Guan, Duqin Zhang, Bin Tan. (2023) Effect of Layered Debranning Processing on the Proximate Composition, Polyphenol Content, and Antioxidant Activity of Whole Grain Wheat. JOURNAL OF FOOD PROCESSING AND PRESERVATION, 2023 (1083867). [PMID:] |
11. Mingyan Liu, Xingzi Yao, Gaowei Zhang, Shengxiang Yi, Xueyong Huang, Fangjian Ning, Liping Luo. (2023) Physicochemical properties, chemical constituents, and antioxidant activity of Eurya honey. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 58 (6): (3458-3468). [PMID:] |
12. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] |
13. Lixia Yang, Zhendong Lu, Jian Lu, Dianhui Wu. (2022) Evaluation of the antioxidant characteristics of craft beer with green tea. JOURNAL OF FOOD SCIENCE, 88 (2): (625-637). [PMID:36576119] |
14. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2023) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). [PMID:36484340] |
15. Zhigui He, Yanfeng Wang, Yan Yan, Shaowei Qin, Huan He, Renjun Mao, Zongsuo Liang. (2022) Dynamic analysis of physiological indices and transcriptome profiling revealing the mechanisms of the allelopathic effects of phenolic acids on Pinellia ternata.. Frontiers in Plant Science, 13 (1039507-1039507). [PMID:36340387] |
16. Yaping Li, Ningning Sun, Songxin Ma, Xin Zhang, Yingfeng Wang, Xingru Li. (2022) Magnetic thermo-responsive branched polymer for fast extraction and enrichment of phenolic acids in olive oil with tunable and enhanced performance. ANALYTICA CHIMICA ACTA, 1229 (340359). [PMID:36156232] |
17. Yang Guangxu, Gong Zhenggang, Luo Xiaolin, Shuai Li. (2022) Revisiting alkaline cupric oxide oxidation method for lignin structural analysis. Frontiers in Bioengineering and Biotechnology, 10 [PMID:36159682] |
18. Duqin Zhang, Yanjun Ye, Bin Tan. (2022) Comparative study of solid-state fermentation with different microbial strains on the bioactive compounds and microstructure of brown rice. FOOD CHEMISTRY, 397 (133735). [PMID:35914455] |
19. Kangling Yin, Li Chen, Feng Liu, Taotao Fan, Yuehang Wu, Shuai Li, Zongcheng Yan. (2022) Liquid–Liquid Equilibrium Data for Novel Aqueous Two-Phase Systems Composed of Betaine-Xylitol Deep Eutectic Solvent + Alcohol (1-Propanol/2-Propanol/tert-Butanol) + Water. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 67 (9): (2475–2485). [PMID:] |
20. Lifen Meng, Zhi Xia, Jingsong Lv, Gaofu Liu, Ye Tan, Qianzhu Li. (2022) Extraction and GC-MS analysis of phenolic acids in rhizosphere soil of Pinellia ternate. Journal of Radiation Research and Applied Sciences, 15 (40). [PMID:] |
21. Guanghe Zhao, Ruifen Zhang, Lihong Dong, Lei Liu, Fei Huang, Xuchao Jia, Mei Deng, Jianwei Chi, Yongxuan Ma, Yanxia Chen, Qin Ma, Mingwei Zhang. (2022) Bound phenolics in rice bran dietary fibre released by different chemical hydrolysis methods: content, composition and antioxidant activities. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 57 (9): (5909-5916). [PMID:] |
22. Ya zhu Wang, Jin Zheng, Muhammad Nawaz, Fan Yang, Jiajun Hu, Min-Tian Gao. (2022) Oligosaccharide-phenolic compound conjugates in soluble polysaccharides from rice straw alleviate ethanol fermentation stresses in Saccharomyces cerevisiae. INDUSTRIAL CROPS AND PRODUCTS, 181 (114782). [PMID:] |
23. Zhan-Qian Ma, Cui-Ping Yi, Na-Na Wu, Bin Tan. (2022) Steaming retains more phenolics, dietary fiber, and antioxidant activities than cooking for rice with different milling processes. CEREAL CHEMISTRY, 99 (3): (664-679). [PMID:] |
24. Shuai Zhang, Qin Ma, Lihong Dong, Xuchao Jia, Lei Liu, Fei Huang, Guang Liu, Zhida Sun, Jianwei Chi, Mingwei Zhang, Ruifen Zhang. (2022) Phenolic profiles and bioactivities of different milling fractions of rice bran from black rice. FOOD CHEMISTRY, 378 (132035). [PMID:35042109] |
25. Kangling Yin, Li Chen, Feng Liu, Taotao Fan, Zongcheng Yan. (2022) Pseudoternary Systems of Deep Eutectic Solvents + tert-Butanol + Water at T = 288.15 K, 298.15 K, and 308.15 K: Liquid–Liquid Equilibrium and Ability for Syringic Acid/Eugenol Separation. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 67 (1): (200–211). [PMID:] |
26. Wenfei Tian, Jingyang Tong, Xiaoyue Zhu, Philipp Fritschi Martin, Yonghui Li, Zhonghu He, Yan Zhang. (2021) Effects of Different Pilot-Scale Milling Methods on Bioactive Components and End-Use Properties of Whole Wheat Flour. Foods, 10 (11): (2857). [PMID:34829138] |