L-Threonine - 99%, high purity , CAS No.72-19-5

75 Citations
Item Number
T108221
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T108221-100g
100g
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250g
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T108221-500g
500g
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Chemical Biology Peptide chemistry

Basic Description

SynonymsH-Thr-OH | L-2-Amino-3-hydroxybutyrate | NSC46701 | CHEBI:16857 | GTPL4785 | L-THREONINE [JAN] | (2S,3R)-rel-2-Amino-3-hydroxybutanoic acid | AKOS015840277 | THREONINE [WHO-DD] | Threonine, L- (8CI) | L-alpha-Amino-beta-hydroxybutyric acid | Threonine, DL
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsL-Threonine is considered an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein that supports gut function and integrity. L-Threonine is necessary for the immune system to function. It is also required for O-linked glycosyl
Storage TempDesiccated
Shipped InNormal
GradeMoligand™
Note25g卖完停产,不再备货
Product Description

L-threonine has been used for the selection of transformed cells. It has also been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster.

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc16a10 Monocarboxylate transporter 10 (73 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAP1 General amino-acid permease GAP1 (481 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc1a5 Amino acid transporter (271 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S,3R)-2-amino-3-hydroxybutanoic acid
INCHI InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
InChi Key AYFVYJQAPQTCCC-GBXIJSLDSA-N
Canonical SMILES CC(C(C(=O)O)N)O
Isomeric SMILES C[C@H]([C@@H](C(=O)O)N)O
RTECS XO8590000
PubChem CID 6288
Molecular Weight 119.13
Beilstein 1721646
Reaxy-Rn 1721646

Certificates

Certificate of Analysis(COA)

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26 results found

Lot NumberCertificate TypeDateItem
D2424432Certificate of AnalysisApr 16, 2024 T108221
D2424431Certificate of AnalysisApr 16, 2024 T108221
D2424430Certificate of AnalysisApr 16, 2024 T108221
D2424429Certificate of AnalysisApr 16, 2024 T108221
D2424428Certificate of AnalysisApr 16, 2024 T108221
D2409288Certificate of AnalysisMar 22, 2024 T108221
D2422452Certificate of AnalysisMar 22, 2024 T108221
D2422453Certificate of AnalysisMar 22, 2024 T108221
D2409287Certificate of AnalysisMar 21, 2024 T108221
D2409289Certificate of AnalysisMar 21, 2024 T108221
K2218728Certificate of AnalysisAug 23, 2022 T108221
L2327022Certificate of AnalysisAug 23, 2022 T108221
K2218736Certificate of AnalysisAug 23, 2022 T108221
K2218737Certificate of AnalysisAug 23, 2022 T108221
K2218740Certificate of AnalysisAug 23, 2022 T108221
K2218745Certificate of AnalysisAug 23, 2022 T108221
L2313065Certificate of AnalysisAug 23, 2022 T108221
A2417099Certificate of AnalysisAug 23, 2022 T108221
I2402454Certificate of AnalysisAug 23, 2022 T108221
J2311101Certificate of AnalysisJan 22, 2022 T108221
B2223237Certificate of AnalysisJan 22, 2022 T108221
B2223234Certificate of AnalysisJan 22, 2022 T108221
B2223232Certificate of AnalysisJan 22, 2022 T108221
B2223224Certificate of AnalysisJan 22, 2022 T108221
B2223183Certificate of AnalysisJan 22, 2022 T108221
B2223168Certificate of AnalysisJan 22, 2022 T108221

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Chemical and Physical Properties

SolubilitySoluble in water. Insoluble in ethanol, ethyl ether and chloroform.
Specific Rotation[α]-28 ° (C=6, H2O)
Melt Point(°C)256 °C (dec.) (lit.)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

RTECS XO8590000
Reaxy-Rn 1721646
Merck Index 9380

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