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L-Threonine - 99%, high purity , CAS No.72-19-5

200 Citations
Item Number
T108221
Grouped product items
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T108221-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$14.90
T108221-250g
250g
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$15.90
T108221-500g
500g
In stock
$16.90
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Chemical Biology Peptide chemistry

Basic Description

SynonymsH-Thr-OH | L-2-Amino-3-hydroxybutyrate | NSC46701 | CHEBI:16857 | GTPL4785 | L-THREONINE [JAN] | (2S,3R)-rel-2-Amino-3-hydroxybutanoic acid | AKOS015840277 | THREONINE [WHO-DD] | Threonine, L- (8CI) | L-alpha-Amino-beta-hydroxybutyric acid | Threonine, DL
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsL-Threonine is considered an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein that supports gut function and integrity. L-Threonine is necessary for the immune system to function. It is also required for O-linked glycosyl
Storage TempDesiccated
Shipped InNormal
GradeMoligand™
Note25g卖完停产，不再备货
Product Description

L-threonine has been used for the selection of transformed cells. It has also been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster.

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc16a10 Monocarboxylate transporter 10 (73 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAP1 General amino-acid permease GAP1 (481 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc1a5 Amino acid transporter (271 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2S,3R)-2-amino-3-hydroxybutanoic acid
INCHI InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
InChi Key AYFVYJQAPQTCCC-GBXIJSLDSA-N
Canonical SMILES CC(C(C(=O)O)N)O
Isomeric SMILES C[C@H]([C@@H](C(=O)O)N)O
RTECS XO8590000
Molecular Weight 119.13
Beilstein 1721646
Reaxy-Rn 1721646

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

39 results found

Lot NumberCertificate TypeDateItem
L2412790Certificate of AnalysisNov 28, 2024 T108221
L2412789Certificate of AnalysisNov 28, 2024 T108221
L2412788Certificate of AnalysisNov 28, 2024 T108221
L2412787Certificate of AnalysisNov 28, 2024 T108221
L2412786Certificate of AnalysisNov 28, 2024 T108221
J2429648Certificate of AnalysisOct 19, 2024 T108221
J2429646Certificate of AnalysisOct 19, 2024 T108221
J2429645Certificate of AnalysisOct 19, 2024 T108221
J2424787Certificate of AnalysisJul 27, 2024 T108221
J2424789Certificate of AnalysisJul 27, 2024 T108221
J2424788Certificate of AnalysisJul 27, 2024 T108221
D2424428Certificate of AnalysisApr 16, 2024 T108221
K2407159Certificate of AnalysisApr 16, 2024 T108221
K2407160Certificate of AnalysisApr 16, 2024 T108221
D2424432Certificate of AnalysisApr 16, 2024 T108221
D2424431Certificate of AnalysisApr 16, 2024 T108221
D2424430Certificate of AnalysisApr 16, 2024 T108221
D2424429Certificate of AnalysisApr 16, 2024 T108221
D2422452Certificate of AnalysisMar 22, 2024 T108221
D2409288Certificate of AnalysisMar 22, 2024 T108221
D2422453Certificate of AnalysisMar 22, 2024 T108221
D2409289Certificate of AnalysisMar 21, 2024 T108221
D2409287Certificate of AnalysisMar 21, 2024 T108221
L2327022Certificate of AnalysisAug 23, 2022 T108221
L2313065Certificate of AnalysisAug 23, 2022 T108221
K2218728Certificate of AnalysisAug 23, 2022 T108221
K2218745Certificate of AnalysisAug 23, 2022 T108221
K2218740Certificate of AnalysisAug 23, 2022 T108221
K2218737Certificate of AnalysisAug 23, 2022 T108221
K2218736Certificate of AnalysisAug 23, 2022 T108221
A2417099Certificate of AnalysisAug 23, 2022 T108221
I2402454Certificate of AnalysisAug 23, 2022 T108221
B2223237Certificate of AnalysisJan 22, 2022 T108221
J2311101Certificate of AnalysisJan 22, 2022 T108221
B2223234Certificate of AnalysisJan 22, 2022 T108221
B2223232Certificate of AnalysisJan 22, 2022 T108221
B2223224Certificate of AnalysisJan 22, 2022 T108221
B2223183Certificate of AnalysisJan 22, 2022 T108221
B2223168Certificate of AnalysisJan 22, 2022 T108221

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Chemical and Physical Properties

SolubilitySoluble in water. Insoluble in ethanol, ethyl ether and chloroform.
Specific Rotation[α]-28 ° (C=6, H2O)
Melt Point(°C)256 °C (dec.) (lit.)

Safety and Hazards(GHS)

RTECS XO8590000
Reaxy-Rn 1721646
Merck Index 9380

Related Documents

 SDS

 Specification Sheet

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FAQs and Articles

FAQ
Editing sugar chains on therapeutic proteins with glycosidase
Categories: Technical articles
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Glycosylation aspartic acid Glycosidase protease dextran

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Guo-Qi Zhang, Wei-ping Liu, Yu-Han Shi, Yu-Xian Zou, Li-Yao Xu, Hui-Ling Cheng, Tao Wang, Wen-Bin Li, Yan Zhao, Zhi-Hong Xu.  (2024)  Intrinsic peroxidase activity of carbon dots derived from expired drugs and its application in automatic detection of total antioxidant capacity.  MICROCHEMICAL JOURNAL,  197  (1): (109720).  [PMID:23948568] [10.1016/j.microc.2023.109720]
2. Lixia Liu, Bingqing Liu, Yongbing Hao, Jia Wang, Xiufang Xu, Xuefang Shang.  (2024)  Theory and experiment: The synthesis and drug application of “ON-OFF-ON” fluorescent probes for copper and biothiols detection.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  239  (12): (115876).  [PMID:38039872] [10.1016/j.jpba.2023.115876]
3. Jierui Yang, Huiting Qiu, Shuang Meng, Yunhui Yang.  (2024)  A sensing platform for ascorbic acid based on the spatial confinement of covalent organic frameworks.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  308  (19): (123687).  [PMID:38042123] [10.1016/j.saa.2023.123687]
4. Chen Zhengpeng, Li Jie, Guo Hongyun, Zhang Yongdong, Ma Mingzhong, Zhou Xing, Yao Wenhuan, Ma Hengchang, Lei Ziqiang, Lu Dedai.  (2023)  In situ gellable poly(amino acid)s with AIE groups for noninterventional embolization therapy and fluorescence imaging of solid tumors.  POLYMER BULLETIN,    (1-17).  [PMID:19273748] [10.1007/s00289-023-05025-8]
5. Jin Yang, Xin Shu, Shangying Qin, Li Huang, Shiqi Cheng, Yilin Wang.  (2024)  A turn-on mode fluorescence detection of cholesterol based on calcein quenched by Co3O4 nanoclusters.  MICROCHEMICAL JOURNAL,  197  (109883).  [PMID:] [10.1016/j.microc.2023.109883]
6. Yaru Hou, Fanyong Yan, Xinyi Bai, Xin Wei, Liang Chen, Yang Fu.  (2024)  Designing advanced 0D/2D heterojunctions of N, S-co-doped carbon dots/Ti3C2Tx MXene nanosheets in electrochemical sensor applications.  CERAMICS INTERNATIONAL,  50  (10735).  [PMID:] [10.1016/j.ceramint.2023.12.389]
7. Shen Zhang, Jinjia Bao, Ling Lv, Yongjie Bai, Yiming Zhang, Yaofang Zhang.  (2024)  Yellow-emitting carbon dots as fluorescent sensors for the rapid determination of curcumin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  309  (123819).  [PMID:38157744] [10.1016/j.saa.2023.123819]
8. Zhiyang Xu, Yinzhou Yan, Xingyuan Wang, Xiaolei Wang, Zhixiang Zhou, Xi Yang, Tianrui Zhai.  (2023)  Determination of Enantiomeric Excess by Optofluidic Microlaser near Exceptional Point.  Advanced Science,    (2308362).  [PMID:38072636] [10.1002/advs.202308362]
9. Tao Song, Weiqi Chen, Yuchi Zhang, Gaohua Situ, Fan Liu, Yao Shen, Weixin Kong, Xinling Zhong, Yan Huang, Shuifei Li, Lin Yang, Shihan Zhang, Sujing Li, Wei Li.  (2024)  Mass transfer and reaction mechanism of CO2 capture into a novel amino acid ionic liquid phase-change absorbent.  SEPARATION AND PURIFICATION TECHNOLOGY,  330  (15): (125538).  [PMID:8026492] [10.1016/j.seppur.2023.125538]
10. Minjie Peng, Yufeng Sun, Wen Zang, Changyong Gao, Lijing Miao, Aiguo Wu, Yujie Zhang.  (2023)  A highly sensitive method for the detection of p-Aminophenol based on Cu–Au nanoparticles and KIO3.  ANALYTICA CHIMICA ACTA,  1283  (19): (341954).  [PMID:37977800] [10.1016/j.aca.2023.341954]
11. Longwei Xi, Qisheng Lu, Yulong Liu, Yulong Gong, Haokun Liu, Junyan Jin, Zhimin Zhang, Yunxia Yang, Xiaoming Zhu, Dong Han, Shouqi Xie.  (2023)  Study on Carbohydrate Metabolism in Adult Zebrafish (Danio rerio).  AQUACULTURE NUTRITION,  2023  (29): (1397508).  [PMID:37901279] [10.1155/2023/1397508]
12. Huan Wang, Wencheng Mu, Siying Wang, Lin Shi, Tianfeng Ma, Yongchang Lu.  (2024)  Facile synthesis of NS-doped carbon dots as sensitive “ON-OFF-ON” fluorescent sensor for Cu2+ and GSH detection.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  305  (123460).  [PMID:37778177] [10.1016/j.saa.2023.123460]
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31. Zhang Jing, Yang Junqing, Luo Ying, Li Jiansha, Gong Tao, Huang Suqiong, Xiong Yan, Jiang Xinhui.  (2022)  Determination of 23 Amino Acids and Amines in Plasma and Cortex of C57BL/6 Mice with HPLC–FLD.  JOURNAL OF CHROMATOGRAPHIC SCIENCE,      [PMID:36572394] [10.1093/chromsci/bmac103]
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38. Xiaozong Dou, Zhenhong Jia, Hongyan Zhang, Chu Chen, Ling Zhang, Jianping Man, Weiyuan Gu.  (2023)  A high-performance fluorescent probe for detection of cysteine in plasma constructed by combining Cu(I) and 2,5-dimercapto-1,3,4-thiadiazole.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  287  (122088).  [PMID:36379157] [10.1016/j.saa.2022.122088]
39. Hao Sun, Weiyun Guo, Yaru Han, Zhifei Gou, Yanmin Liang, Jie Dan, Yi Kang, Jianlong Wang, Wentao Zhang.  (2023)  Food-borne melanoidin based peroxidase mimic for the precise detection of total antioxidant capacity.  MICROCHEMICAL JOURNAL,  184  (108161).  [PMID:] [10.1016/j.microc.2022.108161]
40. Lin Yuan, Lei Jiang, Ze Liu, Yingying Xiang, Fei Song, Yujiao Tu.  (2023)  Selective and sensitive simultaneous detection of tartrazine and Hg2+ based on N-doped yellow-green fluorescent carbon dots.  DYES AND PIGMENTS,  209  (110893).  [PMID:] [10.1016/j.dyepig.2022.110893]
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