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T2AA - ≥98%, high purity , CAS No.1380782-27-3
Discover T2AA by Aladdin Scientific in ≥98% for only $107.90. Available - in Ligands at Aladdin Scientific. Proliferating cell nuclear antigen (PCNA) inhibitor Tags: .
Basic Description Synonyms (βS)-β-Amino-4-(4-hydroxyphenoxy)-3,5-diiodobenzenpropanol Specifications & Purity ≥98% Storage Temp Store at -20°C,Desiccated Shipped In Ice chest + Ice pads Product Description Shipped at Room Temperature. Store at -20°C long term. Store under desiccating conditions.
Associated Targets(Human)
Associated Targets(non-human) Names and Identifiers IUPAC Name 4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol INCHI InChI=1S/C15H15I2NO3/c16-13-6-9(5-10(18)8-19)7-14(17)15(13)21-12-3-1-11(20)2-4-12/h1-4,6-7,10,19-20H,5,8,18H2/t10-/m0/s1 InChi Key NKOSKXJRVWVXRI-JTQLQIEISA-N Canonical SMILES C1=CC(=CC=C1O)OC2=C(C=C(C=C2I)CC(CO)N)I Isomeric SMILES C1=CC(=CC=C1O)OC2=C(C=C(C=C2I)C[C@@H](CO)N)I PubChem CID 71185540 Molecular Weight 511.09
Chemical and Physical Properties Solubility Soluble in DMSO to 100 mM
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P337+P313: IF eye irritation persists: Get medical advice/attention.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P332+P313: IF SKIN irritation occurs: Get medical advice/attention.
P304+P340+P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing.Call a POISON CENTER or doctor. if you feel unwell.
References 1. Ma J et al.. (2020) BARX2 expression is downregulated by CpG island hypermethylation and is associated with suppressed cell proliferation and invasion of gastric cancer cells.. Oncol Rep, 43 (6): (1805-1818). [PMID:32236603 ]
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J2225650