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Tetrahydrobiopterin - ≥98%, high purity , CAS No.17528-72-2, Activator of L-Phenylalanine hydroxylase

Moligand™
≥98%

CAS#: 17528-72-2
Formula: C₉H₁₅N₅O₃
Molecular Weight: 241.25
PubChem CID: 135402045

Item Number

T305191

Grouped product items
SKU	Size	Availability	Price	Qty
T305191-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$294.90
T305191-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$491.90

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L-Phenylalanine hydroxylase Activator

Basic Description

Synonyms	tetrahydrobiopterin\|17528-72-2\|5,6,7,8-tetrahydrobiopterin\|2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one\|CHEBI:15372\|2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-3H-pteridin-4-one\|5,6,7,8-Tetrahydro-2-amino-6-(1,2-dihydroxypro
Specifications & Purity	≥98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	ACTIVATOR
Mechanism of action	Activator of L-Phenylalanine hydroxylase

Names and Identifiers

IUPAC Name	2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-3H-pteridin-4-one
INCHI	InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)
InChi Key	FNKQXYHWGSIFBK-UHFFFAOYSA-N
Canonical SMILES	CC(C(C1CNC2=C(N1)C(=O)NC(=N2)N)O)O
Isomeric SMILES	CC(C(C1CNC2=C(N1)C(=O)NC(=N2)N)O)O
PubChem CID	135402045
Molecular Weight	241.25

CAS Registry No.

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ChEMBL Ligand

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RCSB PDB Ligand

DrugCentral Ligand

Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

References

1. Bélanger-Quintana A, Burlina A, Harding CO, Muntau AC. (2011) Up to date knowledge on different treatment strategies for phenylketonuria.. Mol Genet Metab, 104 Suppl (3): (S19-25). [PMID:21967857]
2. Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL et al.. (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.. Nature, 563 (7732): (564-568). [PMID:30405245]

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Tetrahydrobiopterin - ≥98%, high purity , CAS No.17528-72-2, Activator of L-Phenylalanine hydroxylase

Basic Description

Associated Targets

PAH Tclin Phenylalanine-4-hydroxylase 1 Activities

Names and Identifiers

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Certificate of Analysis(COA)

Safety and Hazards(GHS)

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