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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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T412385-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $19.90 | |
T412385-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 | |
T412385-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $109.90 | |
T412385-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $997.90 | |
T412385-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $379.90 | |
T412385-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $649.90 |
Synonyms | dimethyl-[[4-[[3-(4-methylphenyl)-8,9-dihydro-7H-benzo[7]annulene-6-carbonyl]amino]phenyl]methyl]-(oxan-4-yl)azanium;chloride | TAK 779; TAK779;Takeda 779;Takeda-779;Takeda779 | F84995 | CID 183789 | SCHEMBL48548 | 2H-PyraN,N-dimethyl-N-(4-(2-(p-tolyl)-6, |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | TAK-779 (Takeda 779) is a potent and selective nonpeptide antagonist of CCR5 with Ki of 1.1 nM. TAK-779 is also a CXCR3 antagonist and an effective, selective inhibitor of\xa0R5 HIV-1 with\xa0EC50\xa0and\xa0EC90\xa0of 1.2 nM and 5.7 nM, respectively, in M |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description |
TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | dimethyl-[[4-[[3-(4-methylphenyl)-8,9-dihydro-7H-benzo[7]annulene-6-carbonyl]amino]phenyl]methyl]-(oxan-4-yl)azanium;chloride |
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INCHI | InChI=1S/C33H38N2O2.ClH/c1-24-7-11-27(12-8-24)28-14-13-26-5-4-6-29(22-30(26)21-28)33(36)34-31-15-9-25(10-16-31)23-35(2,3)32-17-19-37-20-18-32;/h7-16,21-22,32H,4-6,17-20,23H2,1-3H3;1H |
InChi Key | VDALIBWXVQVFGZ-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC=C(C=C1)C2=CC3=C(CCCC(=C3)C(=O)NC4=CC=C(C=C4)C[N+](C)(C)C5CCOCC5)C=C2.[Cl-] |
Isomeric SMILES | CC1=CC=C(C=C1)C2=CC3=C(CCCC(=C3)C(=O)NC4=CC=C(C=C4)C[N+](C)(C)C5CCOCC5)C=C2.[Cl-] |
Alternate CAS | 263765-56-6 |
PubChem CID | 183789 |
Molecular Weight | 531.10 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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C2429685 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429686 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429687 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429688 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429689 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429690 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429691 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429692 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429693 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429694 | Certificate of Analysis | Feb 28, 2024 | T412385 |
C2429695 | Certificate of Analysis | Feb 28, 2024 | T412385 |