TAK-779 - 98%, high purity , CAS No.229005-80-5

  • ≥98%
Item Number
T412385
Grouped product items
SKUSizeAvailabilityPrice Qty
T412385-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$19.90
T412385-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
T412385-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
T412385-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$997.90
T412385-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$379.90
T412385-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$649.90

Basic Description

Synonymsdimethyl-[[4-[[3-(4-methylphenyl)-8,9-dihydro-7H-benzo[7]annulene-6-carbonyl]amino]phenyl]methyl]-(oxan-4-yl)azanium;chloride | TAK 779; TAK779;Takeda 779;Takeda-779;Takeda779 | F84995 | CID 183789 | SCHEMBL48548 | 2H-PyraN,N-dimethyl-N-(4-(2-(p-tolyl)-6,
Specifications & Purity≥98%
Biochemical and Physiological MechanismsTAK-779 (Takeda 779) is a potent and selective nonpeptide antagonist of CCR5 with Ki of 1.1 nM. TAK-779 is also a CXCR3 antagonist and an effective, selective inhibitor of\xa0R5 HIV-1 with\xa0EC50\xa0and\xa0EC90\xa0of 1.2 nM and 5.7 nM, respectively, in M
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).

Associated Targets(Human)

CCR1 Tchem C-C chemokine receptor type 1 (1730 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCR3 Tchem C-C chemokine receptor type 3 (1666 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCR4 Tclin C-C chemokine receptor type 4 (2819 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCR5 Tclin C-C chemokine receptor type 5 (5640 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCR2 Tchem C-C chemokine receptor type 2 (5628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CXCR3 Tchem C-X-C chemokine receptor type 3 (2736 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DU-145 (51482 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LNCaP (8286 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CCR7 Tchem C-C chemokine receptor type 7 (36 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHO (4503 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name dimethyl-[[4-[[3-(4-methylphenyl)-8,9-dihydro-7H-benzo[7]annulene-6-carbonyl]amino]phenyl]methyl]-(oxan-4-yl)azanium;chloride
INCHI InChI=1S/C33H38N2O2.ClH/c1-24-7-11-27(12-8-24)28-14-13-26-5-4-6-29(22-30(26)21-28)33(36)34-31-15-9-25(10-16-31)23-35(2,3)32-17-19-37-20-18-32;/h7-16,21-22,32H,4-6,17-20,23H2,1-3H3;1H
InChi Key VDALIBWXVQVFGZ-UHFFFAOYSA-N
Canonical SMILES CC1=CC=C(C=C1)C2=CC3=C(CCCC(=C3)C(=O)NC4=CC=C(C=C4)C[N+](C)(C)C5CCOCC5)C=C2.[Cl-]
Isomeric SMILES CC1=CC=C(C=C1)C2=CC3=C(CCCC(=C3)C(=O)NC4=CC=C(C=C4)C[N+](C)(C)C5CCOCC5)C=C2.[Cl-]
Alternate CAS 263765-56-6
PubChem CID 183789
Molecular Weight 531.10

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
C2429685Certificate of AnalysisFeb 28, 2024 T412385
C2429686Certificate of AnalysisFeb 28, 2024 T412385
C2429687Certificate of AnalysisFeb 28, 2024 T412385
C2429688Certificate of AnalysisFeb 28, 2024 T412385
C2429689Certificate of AnalysisFeb 28, 2024 T412385
C2429690Certificate of AnalysisFeb 28, 2024 T412385
C2429691Certificate of AnalysisFeb 28, 2024 T412385
C2429692Certificate of AnalysisFeb 28, 2024 T412385
C2429693Certificate of AnalysisFeb 28, 2024 T412385
C2429694Certificate of AnalysisFeb 28, 2024 T412385
C2429695Certificate of AnalysisFeb 28, 2024 T412385

Show more⌵

Related Documents

Solution Calculators