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TAK-779 - 98%, high purity , CAS No.229005-80-5

≥98%

CAS#: 229005-80-5
Formula: C₃₃H₃₉ClN₂O₂
Molecular Weight: 531.10
PubChem CID: 183789

Item Number

T412385

Grouped product items
SKU	Size	Availability	Price
T412385-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$19.90
T412385-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90
T412385-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$109.90
T412385-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$997.90
T412385-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$379.90
T412385-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$649.90

View related series

CCR HIV CXCR

Basic Description

Synonyms	TAK-779 \| 229005-80-5 \| Takeda 779 \| TAK 799 \| N,N-Dimethyl-N-(4-(((2-(4-methylphenyl)-6,7-dihydro-5H-benzocyclohepten-8-yl)carbonyl)amino)benzyl)tetrahydro-2H-pyran-4-aminium chloride \| BQW1Y9KIIP \| TAK 779 \| CHEMBL41275 \| dimethyl-[[4-[[3-(4-methylphenyl)-8,9-dihydro-7
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	TAK-779 (Takeda 779) is a potent and selective nonpeptide antagonist of CCR5 with Ki of 1.1 nM. TAK-779 is also a CXCR3 antagonist and an effective, selective inhibitor of\xa0R5 HIV-1 with\xa0EC50\xa0and\xa0EC90\xa0of 1.2 nM and 5.7 nM, respectively, in M
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).

Associated Targets(Human)

CXCR3 Tchem C-X-C chemokine receptor type 3 (0 Activities)

Discover Target: CXCR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCR2 Tchem C-C chemokine receptor type 2 (26 Activities)

Discover Target: CCR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCR7 Tchem C-C chemokine receptor type 7 (1 Activities)

Discover Target: CCR7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCR4 Tclin C-C chemokine receptor type 4 (0 Activities)

Discover Target: CCR4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCR3 Tchem C-C chemokine receptor type 3 (0 Activities)

Discover Target: CCR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCR5 Tclin C-C chemokine receptor type 5 (13 Activities)

Discover Target: CCR5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCR1 Tchem C-C chemokine receptor type 1 (0 Activities)

Discover Target: CCR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCR1 Tchem C-C chemokine receptor type 1 (1730 Activities)

Discover Target: CCR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCR3 Tchem C-C chemokine receptor type 3 (1666 Activities)

Discover Target: CCR3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCR4 Tclin C-C chemokine receptor type 4 (2819 Activities)

Discover Target: CCR4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCR5 Tclin C-C chemokine receptor type 5 (5640 Activities)

Discover Target: CCR5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCR2 Tchem C-C chemokine receptor type 2 (5628 Activities)

Discover Target: CCR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CXCR3 Tchem C-X-C chemokine receptor type 3 (2736 Activities)

Discover Target: CXCR3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DU-145 (51482 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PC-3 (62116 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LNCaP (8286 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CCR7 Tchem C-C chemokine receptor type 7 (36 Activities)

Discover Target: CCR7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Human immunodeficiency virus 1 (70413 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CHO (4503 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

env Envelope glycoprotein gp160 (34 Activities)

Discover Target: env

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	dimethyl-[[4-[[3-(4-methylphenyl)-8,9-dihydro-7H-benzo[7]annulene-6-carbonyl]amino]phenyl]methyl]-(oxan-4-yl)azanium;chloride
INCHI	InChI=1S/C33H38N2O2.ClH/c1-24-7-11-27(12-8-24)28-14-13-26-5-4-6-29(22-30(26)21-28)33(36)34-31-15-9-25(10-16-31)23-35(2,3)32-17-19-37-20-18-32;/h7-16,21-22,32H,4-6,17-20,23H2,1-3H3;1H
InChi Key	VDALIBWXVQVFGZ-UHFFFAOYSA-N
Canonical SMILES	CC1=CC=C(C=C1)C2=CC3=C(CCCC(=C3)C(=O)NC4=CC=C(C=C4)C[N+](C)(C)C5CCOCC5)C=C2.[Cl-]
Isomeric SMILES	CC1=CC=C(C=C1)C2=CC3=C(CCCC(=C3)C(=O)NC4=CC=C(C=C4)C[N+](C)(C)C5CCOCC5)C=C2.[Cl-]
Alternate CAS	263765-56-6
PubChem CID	183789
Molecular Weight	531.10

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

11 results found

Lot Number	Certificate Type	Date	Item
C2429685	Certificate of Analysis	Feb 28, 2024	T412385
C2429686	Certificate of Analysis	Feb 28, 2024	T412385
C2429687	Certificate of Analysis	Feb 28, 2024	T412385
C2429688	Certificate of Analysis	Feb 28, 2024	T412385
C2429689	Certificate of Analysis	Feb 28, 2024	T412385
C2429690	Certificate of Analysis	Feb 28, 2024	T412385
C2429691	Certificate of Analysis	Feb 28, 2024	T412385
C2429692	Certificate of Analysis	Feb 28, 2024	T412385
C2429693	Certificate of Analysis	Feb 28, 2024	T412385
C2429694	Certificate of Analysis	Feb 28, 2024	T412385
C2429695	Certificate of Analysis	Feb 28, 2024	T412385

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