Major tanshinone isolated fromSalvia miltiorrhiza. Inhibits NF-κB and AP-1 DNA binding. Exhibits cytotoxic activity in a number of different cancer cells. Inhibitsβ-amyloid aggregation and protects PC12 cells fromβ-amyloid-induced apoptosis. Displays anti
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Product Description
Tanshinone IIA (Dan Shen ketone), vasoactive cardioprotective drug, is used in a wide variety of studies to asses is potential therapeutic value and mechanisms of action which include inhibiting LDL oxidation, monocyte adhesion to endothelium, smooth muscle cell migration and proliferation, macrophage cholesterol accumulation, proinflammatory cytokine expression and platelet aggregation.
F2405524