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TAPI-1 - 10mM in DMSO, high purity , CAS No.171235-71-5

Item Number

T422110

Grouped product items
SKU	Size	Availability	Price	Qty
T422110-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$241.90

TNF-α processing inhibitor

Basic Description

Synonyms	N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-alaninamide
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Stable, selective inhibitor of TNF-α processing (IC 50 = ~100 nM).\xa0 Inhibits TACE (P< 0.01) and other metalloproteases in vivo .
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads

Adam17 ADAM17 (14 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IUPAC Name	N-[(2S)-1-[[(2S)-1-(2-aminoethylamino)-1-oxopropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide
INCHI	InChI=1S/C26H37N5O5/c1-16(2)12-21(15-23(32)31-36)25(34)30-22(26(35)29-17(3)24(33)28-11-10-27)14-18-8-9-19-6-4-5-7-20(19)13-18/h4-9,13,16-17,21-22,36H,10-12,14-15,27H2,1-3H3,(H,28,33)(H,29,35)(H,30,34)(H,31,32)/t17-,21?,22-/m0/s1
InChi Key	AWNBSWDIOCXWJW-OWHMDLSXSA-N
Canonical SMILES	CC(C)CC(CC(=O)NO)C(=O)NC(CC1=CC2=CC=CC=C2C=C1)C(=O)NC(C)C(=O)NCCN
Isomeric SMILES	C[C@@H](C(=O)NCCN)NC(=O)[C@H](CC1=CC2=CC=CC=C2C=C1)NC(=O)C(CC(C)C)CC(=O)NO
PubChem CID	9827273
Molecular Weight	499.6

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