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Taprostene - ≥95%, high purity , CAS No.108945-35-3, Agonist of IP receptor

Item Number

T340466

Grouped product items
SKU	Size	Availability	Price	Qty
T340466-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$170.90
T340466-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$612.90

a highly selective agonist of the prostanoid receptor IP1

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Basic Description

Synonyms	Taprostene\|108945-35-3\|Taprostene [INN]\|7MS1HEY2IZ\|Rheocyclan\|3-[(Z)-[(3aR,4R,5R,6aS)-4-[(E,3S)-3-cyclohexyl-3-hydroxyprop-1-enyl]-5-hydroxy-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]methyl]benzoic acid\|Taprostenum [Latin]\|Taprosteno [Spanish]\|T
Specifications & Purity	≥95%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of IP receptor
Product Description	Taprostene is a highly selective agonist to the IP\|1\|prostanoid receptor. It is a stable prostacyclin (PGI\|2\|) analog.

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	3-[(Z)-[(3aR,4R,5R,6aS)-4-[(E,3S)-3-cyclohexyl-3-hydroxyprop-1-enyl]-5-hydroxy-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]methyl]benzoic acid
INCHI	InChI=1S/C24H30O5/c25-21(16-6-2-1-3-7-16)10-9-19-20-13-18(29-23(20)14-22(19)26)12-15-5-4-8-17(11-15)24(27)28/h4-5,8-12,16,19-23,25-26H,1-3,6-7,13-14H2,(H,27,28)/b10-9+,18-12-/t19-,20-,21-,22-,23+/m1/s1
InChi Key	ZLJOKYGJNOQXDP-OZUBPDBUSA-N
Canonical SMILES	C1CCC(CC1)C(C=CC2C(CC3C2CC(=CC4=CC(=CC=C4)C(=O)O)O3)O)O
Isomeric SMILES	C1CCC(CC1)[C@@H](/C=C/[C@H]2[C@@H](C[C@H]3[C@@H]2C/C(=C/C4=CC(=CC=C4)C(=O)O)/O3)O)O
PubChem CID	5311243
Molecular Weight	398.49

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Solubility	Soluble in Water: 26 mg/mL

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