17374-26-4|4,5,6,7-tetrabromobenzotriazole|TBB|4,5,6,7-Tetrabromo-1H-benzotriazole|TBBt|4,5,6,7-tetrabromo-2H-benzotriazole|4,5,6,7-Tetrabromo-1H-benzo[d][1,2,3]triazole|Casein Kinase II Inhibitor I|TETRABROMO-2-BENZOTRIAZOLE|NSC 231634|CHEMBL177820|NSC23
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
TBB is a cell-permeable benzotriazolo compound that acts as a highly selective ATP/GTP-competitive protein kinase inhibitor. It has been shown to specifically inhibit casein kinase IIα (CK2α) and dual-specificity tyrosine-(Y)-phosphorylation regulated kin
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Product Description
TBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively). A highly selective CK2α, Dyrk1A, and NS3 viral helicase inhibitor.
Associated Targets
CNKSR3Tbio Connector enhancer of kinase suppressor of ras 3 0 Activities
