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TCID - 10mM in DMSO, high purity , CAS No.30675-13-9

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TCID - 10mM in DMSO, high purity , CAS No.30675-13-9

1 Citations

Moligand™

10mM in DMSO

CAS#: 30675-13-9
Formula: C₉H₂Cl₄O₂
Molecular Weight: 283.92
PubChem CID: 2729042

Item Number

T423175

Grouped product items
SKU	Size	Availability	Price	Qty
T423175-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$241.90

Potent and selective ubiquitin C-terminal hydrolase-L3 inhibitor

Basic Description

Synonyms	30675-13-9 \| TCID \| 4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione \| 4,5,6,7-Tetrachloroindan-1,3-dione \| UCH-L3 Inhibitor \| 4,5,6,7-tetrachloroindene-1,3-dione \| 4,5,6,7-Tetrachloroindane-1,3-dione \| 1H-Indene-1,3(2H)-dione, 4,5,6,7-tetrachloro- \| CHEMBL1241028 \| compound 6
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	TCID is a cell penetrant potent and specific inhibitor of UCH-L3 (Ubiquitin carboxyl-terminal hydrolase isozyme L3). TCID is used to distinguish between UCH-L1 and UCH-L3 activities in cells.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™

Associated Targets(Human)

UCHL3 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L3 (2 Activities)

Discover Target: UCHL3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UCHL1 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L1 (107 Activities)

Discover Target: UCHL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UCHL3 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L3 (50 Activities)

Discover Target: UCHL3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	4,5,6,7-tetrachloroindene-1,3-dione
INCHI	InChI=1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2
InChi Key	IDLAOWFFKWRNHB-UHFFFAOYSA-N
Canonical SMILES	C1C(=O)C2=C(C1=O)C(=C(C(=C2Cl)Cl)Cl)Cl
Isomeric SMILES	C1C(=O)C2=C(C1=O)C(=C(C(=C2Cl)Cl)Cl)Cl
PubChem CID	2729042
Molecular Weight	283.92

Certificates

Certificate of Analysis(COA)

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Citations of This Product

1. Shaowei Bo, Dong Zhang, Mengjie Ma, Xukai Mo, Julia Stabinska, Michael T. McMahon, Changzheng Shi, Liangping Luo. (2023) Acyl Hydrazides and Acyl Hydrazones as High-Performance Chemical Exchange Saturation Transfer MRI Contrast Agents. Pharmaceuticals, 16 (5): (639). [PMID:37242423]

References

1. Shaowei Bo, Dong Zhang, Mengjie Ma, Xukai Mo, Julia Stabinska, Michael T. McMahon, Changzheng Shi, Liangping Luo. (2023) Acyl Hydrazides and Acyl Hydrazones as High-Performance Chemical Exchange Saturation Transfer MRI Contrast Agents. Pharmaceuticals, 16 (5): (639). [PMID:37242423]

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