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TCID - 10mM in DMSO, high purity , CAS No.30675-13-9

2 Citations

Moligand™

10mM in DMSO

CAS#: 30675-13-9
Formula: C₉H₂Cl₄O₂
Molecular Weight: 283.92
PubChem CID: 2729042

Item Number

T423175

Grouped product items
SKU	Size	Availability	Price	Qty
T423175-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$241.90

Potent and selective ubiquitin C-terminal hydrolase-L3 inhibitor

Basic Description

Synonyms	30675-13-9 \| TCID \| 4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione \| 4,5,6,7-Tetrachloroindan-1,3-dione \| UCH-L3 Inhibitor \| 4,5,6,7-tetrachloroindene-1,3-dione \| 4,5,6,7-Tetrachloroindane-1,3-dione \| 1H-Indene-1,3(2H)-dione, 4,5,6,7-tetrachloro- \| CHEMBL1241028 \| compound 6
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	TCID is a cell penetrant potent and specific inhibitor of UCH-L3 (Ubiquitin carboxyl-terminal hydrolase isozyme L3). TCID is used to distinguish between UCH-L1 and UCH-L3 activities in cells.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™

Associated Targets(Human)

UCHL3 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L3 (2 Activities)

Discover Target: UCHL3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UCHL1 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L1 (107 Activities)

Discover Target: UCHL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UCHL3 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L3 (50 Activities)

Discover Target: UCHL3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	4,5,6,7-tetrachloroindene-1,3-dione
INCHI	InChI=1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2
InChi Key	IDLAOWFFKWRNHB-UHFFFAOYSA-N
Canonical SMILES	C1C(=O)C2=C(C1=O)C(=C(C(=C2Cl)Cl)Cl)Cl
Isomeric SMILES	C1C(=O)C2=C(C1=O)C(=C(C(=C2Cl)Cl)Cl)Cl
PubChem CID	2729042
Molecular Weight	283.92

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Shaowei Bo, Dong Zhang, Mengjie Ma, Xukai Mo, Julia Stabinska, Michael T. McMahon, Changzheng Shi, Liangping Luo. (2023) Acyl Hydrazides and Acyl Hydrazones as High-Performance Chemical Exchange Saturation Transfer MRI Contrast Agents. Pharmaceuticals, 16 (5): (639). [PMID:37242423] [10.3390/ph16050639]
2. Wang Qian, He Yuan, Lu Rui, Wang Wen-Ming, Yang Ke-Wu, Fan Hai Ming, Jin Yi, Blackburn G. Michael. (2018) Thermokinetic profile of NDM-1 and its inhibition by small carboxylic acids. BIOSCIENCE REPORTS, 38 (2): [PMID:29507059] [10.1042/BSR20180244]

References

1. Shaowei Bo, Dong Zhang, Mengjie Ma, Xukai Mo, Julia Stabinska, Michael T. McMahon, Changzheng Shi, Liangping Luo. (2023) Acyl Hydrazides and Acyl Hydrazones as High-Performance Chemical Exchange Saturation Transfer MRI Contrast Agents. Pharmaceuticals, 16 (5): (639). [PMID:37242423] [10.3390/ph16050639]
2. Wang Qian, He Yuan, Lu Rui, Wang Wen-Ming, Yang Ke-Wu, Fan Hai Ming, Jin Yi, Blackburn G. Michael. (2018) Thermokinetic profile of NDM-1 and its inhibition by small carboxylic acids. BIOSCIENCE REPORTS, 38 (2): [PMID:29507059] [10.1042/BSR20180244]

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TCID - 10mM in DMSO, high purity , CAS No.30675-13-9

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Related Documents

Citations of This Product

References

Solution Calculators

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