TCN 201 - 10mM in DMSO, high purity , CAS No.852918-02-6

Item Number
T426304
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T426304-1ml
1ml
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$69.90

GluN1/GluN2A-selective NMDA antagonist

Basic Description

Synonyms852918-02-6 | tcn-201 | TCN 201 | N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4-fluorobenzenesulfonamide | 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide | TCN201 | CHEMBL2333945 | N-[[4-(benzamidocarbamoyl)phenyl]methyl]-
Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological MechanismsNMDA受体拮抗剂在人重组GluN1 / GluN2A(以前为NR1 / NR2A)和GluN1中对含有GluN1 / GluN2B(以前为NR1 / NR2B)的受体(pIC50分别为6.8和<4.3)具有选择性,对GluN1 / GluN2A(以前为NR1 / NR2A)有选择性。 / GluN2B(以前称为NR1 / NR2B)FLIPR / Ca2 +分析)。有关最新命名约定,请参阅IUPHAR药理学指南。
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™

Associated Targets(Human)

GRIN2A Tclin Glutamate receptor ionotropic, NMDA 2A (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2A Tclin Glutamate [NMDA] receptor subunit epsilon 1 (112 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN2B Tclin Glutamate [NMDA] receptor subunit epsilon 2 (467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN2C Tclin Glutamate [NMDA] receptor subunit epsilon 3 (47 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U2OS (164939 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate NMDA receptor; GRIN1/GRIN2B (726 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Ionotropic glutamate receptor NMDA 1/2D (23 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK-293T (167025 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin2d Glutamate [NMDA] receptor subunit epsilon 4 (130 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor; Grin1/Grin2a (798 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor; Grin1/Grin2c (1127 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Molecular Weight 461.89

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators