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TCN 201 - 10mM in DMSO, high purity , CAS No.852918-02-6
GluN1/GluN2A-selective NMDA antagonist
Basic Description
Synonyms | 852918-02-6 | tcn-201 | TCN 201 | N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4-fluorobenzenesulfonamide | 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide | TCN201 | CHEMBL2333945 | N-[[4-(benzamidocarbamoyl)phenyl]methyl]- |
Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | NMDA受体拮抗剂在人重组GluN1 / GluN2A(以前为NR1 / NR2A)和GluN1中对含有GluN1 / GluN2B(以前为NR1 / NR2B)的受体(pIC50分别为6.8和<4.3)具有选择性,对GluN1 / GluN2A(以前为NR1 / NR2A)有选择性。 / GluN2B(以前称为NR1 / NR2B)FLIPR / Ca2 +分析)。有关最新命名约定,请参阅IUPHAR药理学指南。 |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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