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TCN 201 - 10mM in DMSO, high purity , CAS No.852918-02-6

Item Number
T426304
Grouped product items
SKUSizeAvailabilityPrice Qty
T426304-1ml
1ml
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$69.90
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GluN1/GluN2A-selective NMDA antagonist

Basic Description

Synonyms852918-02-6 | tcn-201 | TCN 201 | N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4-fluorobenzenesulfonamide | 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide | TCN201 | CHEMBL2333945 | N-[[4-(benzamidocarbamoyl)phenyl]methyl]-
Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological MechanismsNMDA受体拮抗剂在人重组GluN1 / GluN2A（以前为NR1 / NR2A）和GluN1中对含有GluN1 / GluN2B（以前为NR1 / NR2B）的受体（pIC50分别为6.8和<4.3）具有选择性，对GluN1 / GluN2A（以前为NR1 / NR2A）有选择性。 / GluN2B（以前称为NR1 / NR2B）FLIPR / Ca2 +分析）。有关最新命名约定，请参阅IUPHAR药理学指南。
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™

Associated Targets(Human)

GRIN2A Tclin Glutamate receptor ionotropic, NMDA 2A (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRIN2A Tclin Glutamate [NMDA] receptor subunit epsilon 1 (112 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN2B Tclin Glutamate [NMDA] receptor subunit epsilon 2 (467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN2C Tclin Glutamate [NMDA] receptor subunit epsilon 3 (47 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U2OS (164939 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate NMDA receptor; GRIN1/GRIN2B (726 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Ionotropic glutamate receptor NMDA 1/2D (23 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK-293T (167025 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin2d Glutamate [NMDA] receptor subunit epsilon 4 (130 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor; Grin1/Grin2a (798 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor; Grin1/Grin2c (1127 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Molecular Weight 461.89

Certificates

Certificate of Analysis(COA)

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Related Documents

 SDS

 Specification Sheet

Solution Calculators

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