JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

Home
Applications
Targets
Ligand-gated ion channels
Ionotropic glutamate receptors
TCN 213 - 98%, high purity , CAS No.556803-08-8, Allosteric modulator of GluN2A

TCN 213 - 98%, high purity , CAS No.556803-08-8, Allosteric modulator of GluN2A

Item Number

T286921

Grouped product items
SKU	Size	Availability	Price
T286921-5mg	5mg	In stock	$117.90
T286921-10mg	10mg	In stock	$187.90
T286921-25mg	25mg	In stock	$375.90
T286921-50mg	50mg	In stock	$612.90
T286921-100mg	100mg	In stock	$969.90
T286921-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$2,182.90

NMDA antagonist; selective for GluN2A over GluN2B containing receptors

View related series

Basic Description

Synonyms	N-(Cyclohexylmethyl)-2-[(5-[(phenylmethyl)amino]-1,3,4-thiadiazol-2-yl}thio]acetamide;2-((5-(benzylamino)-1,3,4-thiadiazol-2-yl)thio)-N-(cyclohexylmethyl)acetamide
Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of GluN2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	2-[[5-(benzylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(cyclohexylmethyl)acetamide
INCHI	InChI=1S/C18H24N4OS2/c23-16(19-11-14-7-3-1-4-8-14)13-24-18-22-21-17(25-18)20-12-15-9-5-2-6-10-15/h2,5-6,9-10,14H,1,3-4,7-8,11-13H2,(H,19,23)(H,20,21)
InChi Key	XBAZPYFIYYCZBO-UHFFFAOYSA-N
Canonical SMILES	C1CCC(CC1)CNC(=O)CSC2=NN=C(S2)NCC3=CC=CC=C3
Isomeric SMILES	C1CCC(CC1)CNC(=O)CSC2=NN=C(S2)NCC3=CC=CC=C3
PubChem CID	2608149
MeSH Entry Terms	N-(cyclohexylmethyl)-2-((5-((phenylmethyl)amino)-1,3,4-thiadiazol-2-yl)thio)acetamide;TCN 213
Molecular Weight	376.54

Enter Lot Number to search for COA:

Solubility	Solvent:DMSO, Max Conc. mg/mL: 28.24, Max Conc. mM: 75; Solvent:ethanol, Max Conc. mg/mL: 3.77, Max Conc. mM: 10

1. McKay S, Griffiths NH, Butters PA, Thubron EB, Hardingham GE, Wyllie DJ. (2012) Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist.. Br J Pharmacol, 166 (3): (924-37). [PMID:22022974]

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.