TCS 1105 - ≥99%(HPLC), high purity , CAS No.185391-33-7

  • ≥99%(HPLC)
Item Number
T286790
Grouped product items
SKUSizeAvailabilityPrice Qty
T286790-5mg
5mg
In stock
$83.90
T286790-10mg
10mg
In stock
$129.90
T286790-25mg
25mg
In stock
$290.90
T286790-50mg
50mg
In stock
$551.90
T286790-100mg
100mg
In stock
$991.90
T286790-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,231.90

GABAAα2 benzodiazepine agonist

Basic Description

Specifications & Purity≥99%(HPLC)
Biochemical and Physiological MechanismsGABAAbenzodiazepine receptor (BZR) ligand. Acts as an agonist atα2and antagonist atα1benzodiazepine receptors (Kivalues are 118 and 245 nM respectively). Anxiolytic agent lacking sedative activity.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

GABRA2 Tclin GABA receptor alpha-2 subunit (271 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gabrp GABA-A receptor; anion channel (5731 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gabrg2 GABA-A receptor; alpha-1/beta-2/gamma-2 (554 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name N-[(4-fluorophenyl)methyl]-2-(1H-indol-3-yl)-2-oxoacetamide
INCHI InChI=1S/C17H13FN2O2/c18-12-7-5-11(6-8-12)9-20-17(22)16(21)14-10-19-15-4-2-1-3-13(14)15/h1-8,10,19H,9H2,(H,20,22)
InChi Key VWCCHJFFYCGXFL-UHFFFAOYSA-N
Canonical SMILES C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NCC3=CC=C(C=C3)F
Isomeric SMILES C1=CC=C2C(=C1)C(=CN2)C(=O)C(=O)NCC3=CC=C(C=C3)F
PubChem CID 2986030
Molecular Weight 296.3

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
I2219280Certificate of AnalysisJul 01, 2022 T286790
I2219281Certificate of AnalysisJul 01, 2022 T286790
I2219282Certificate of AnalysisJul 01, 2022 T286790
I2219354Certificate of AnalysisJul 01, 2022 T286790
I2219355Certificate of AnalysisJul 01, 2022 T286790

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 29.63, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 5.93, Max Conc. mM: 20

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Solution Calculators