Tebipenem is an orally available carbapenem antibiotic , shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa .
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Product Description
Tebipenem is an orally available carbapenem antibiotic , shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa .
In Vitro
Tebipenem exhibits slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin, and apparent K m and k cat values of 0.8 μM and 0.03 min -1 , respectively. Tebipenem shows potent activity against B. pseudomallei , with MIC 50 and MIC 90 values of both 2 mg/L. Tebipenem shows good activity against S. pneumoniae , with the MIC range of ≤0.25 μg/mL in all of the S. pneumoniae isolates. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
