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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | Tectorigenin | 548-77-6 | Tectorigenine | 4',5,7-Trihydroxy-6-methoxyisoflavone | 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one | K 251T | 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxychromen-4-one | 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl) |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
Associated Targets(Human)
CAT Tbio Catalase (0 Activities)
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
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XDH Tclin Xanthine dehydrogenase (1038 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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MCF7 (126967 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
Hepatitis B virus (7925 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxychromen-4-one |
|---|---|
| INCHI | InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3 |
| InChi Key | OBBCRPUNCUPUOS-UHFFFAOYSA-N |
| Canonical SMILES | COC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O |
| Isomeric SMILES | COC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O |
| Alternate CAS | 548-77-6 |
| PubChem CID | 5281811 |
| MeSH Entry Terms | 4',5',7-trihydroxy-6-methoxyisoflavone;tectorigenin |
| Molecular Weight | 300.263 |
Certificates
Certificate of Analysis(COA)
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Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H302:Harmful if swallowed |
| Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
Related Documents
Citations of This Product
| 1. Feng Wei. (2021) Tectorigenin attenuates cognitive impairments in mice with chronic cerebral ischemia by inhibiting the TLR4/NF-κB signaling pathway. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 85 (7): (1665-1674). [PMID:34014269] [10.1093/bbb/zbab086] |
References
| 1. Feng Wei. (2021) Tectorigenin attenuates cognitive impairments in mice with chronic cerebral ischemia by inhibiting the TLR4/NF-κB signaling pathway. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 85 (7): (1665-1674). [PMID:34014269] [10.1093/bbb/zbab086] |