Basic Description

Synonyms	NCGC00379072-02 \| AKOS025401974 \| DA-7157 \| (5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxymethyl)-1,3-oxazolidin-2-one \| SMR002530445 \| TR 700 \| EN300-18530167 \| torezolid; Sivextro \| (5R)-3-(3-fluoro-4-(6-(2-methyl-2H-te
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	Torezolid (also known as TR-701 and now tedizolid) is an oxazolidinone drug in phase-II clinical trials for complicated skin and skin-structure infections (cSSSI), including those caused by Methicillin-resistant Staphylococcus aureus (MRS
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Product Description	Torezolid (TR-701; tedizolid) is a novel oxazolidinone for gram-positive infections An antibacterial

Product Properties

ALogP	1.4

Associated Targets(Human)

MAOA Tclin Monoamine oxidase A (11911 Activities)

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MAOB Tclin Monoamine oxidase B (8835 Activities)

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Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

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Streptococcus pneumoniae (31063 Activities)

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Enterococcus (1748 Activities)

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Streptococcus viridans (303 Activities)

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Bacteroides fragilis (1445 Activities)

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Bacteroides thetaiotaomicron (562 Activities)

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Peptostreptococcus anaerobius (347 Activities)

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Staphylococcus aureus (210822 Activities)

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Staphylococcus epidermidis (22802 Activities)

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Staphylococcus hominis (482 Activities)

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Moraxella catarrhalis (3334 Activities)

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Haemophilus influenzae (8812 Activities)

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Phocaeicola vulgatus (440 Activities)

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Staphylococcus (1598 Activities)

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Streptococcus sp. (212 Activities)

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Streptococcus agalactiae (1777 Activities)

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Streptococcus pyogenes (16140 Activities)

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Enterococcus faecium (13803 Activities)

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Clostridium perfringens (1165 Activities)

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Listeria monocytogenes (2626 Activities)

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Enterococcus faecalis (29875 Activities)

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Mus musculus (284745 Activities)

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Enterococcus sp. (726 Activities)

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Bacteroides ovatus (282 Activities)

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Staphylococcus sp. (496 Activities)

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Parvimonas micra (315 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Corynebacterium jeikeium (106 Activities)

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Mammaliicoccus sciuri (248 Activities)

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Porphyromonas asaccharolytica (102 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
INCHI	InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1
InChi Key	XFALPSLJIHVRKE-GFCCVEGCSA-N
Canonical SMILES	CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4CC(OC4=O)CO)F
Isomeric SMILES	CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4C[C@@H](OC4=O)CO)F
PubChem CID	11234049
Molecular Weight	370.34

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Warning
Hazard Statements	H373:Causes damage to organs through prolonged or repeated exposure H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P260:Do not breathe dust/fume/gas/mist/vapors/spray. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell.

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Tedizolid - 10mM in DMSO, high purity , CAS No.856866-72-3

Basic Description

Product Properties

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Safety and Hazards(GHS)

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator